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441 articles

April 20261

March 202615

Clinical ResearchPsychiatryOpen access

Cognitive and balance dual-task training for middle-aged and older individuals with schizophrenia: a three-arm randomized controlled trial.

This single-blind, three-arm randomized controlled trial evaluated cognitive-and-balance dual-task training using CogBals in 84 middle-aged and older adults with schizophrenia recruited from psychiatric rehabilitation…

Eur Arch Psychiatry Clin NeurosciMar 30, 2026Read summary
Clinical ResearchGeriatricsOpen access

Social Isolation and Loneliness Among Older Asian Immigrants Through the Lens of Sense of Coherence: Systematic Review of Qualitative Studies.

This systematic review synthesised 10 qualitative papers on community-living Asian immigrants aged 65 and over in Western countries who experienced social isolation and loneliness.

J Adv NursMar 27, 2026Read summary
Case ReportRheumatology

New-onset of polymyalgia rheumatica in an elderly patient with calcium pyrophosphate deposition (CPPD) disease.

An 87-year-old woman presented with fever and knee pain. Calcium pyrophosphate crystals in synovial fluid supported a diagnosis of CPPD disease, and NSAIDs resolved her knee arthritis and inflammatory signs.

Fukushima J Med SciMar 25, 2026Read case
Clinical ResearchGeriatrics

Adherence to the Mediterranean diet and frailty and disability in older people: A systematic review and meta-analysis featured in the Italian National Guidelines "La Dieta Mediterranea".

This systematic review and meta-analysis examined whether Mediterranean diet adherence is associated with frailty and disability in older people.

NutritionMar 22, 2026Read summary
Clinical ResearchGeriatricsOpen access

Combined resistance exercise and essential amino acid intake enhance follistatin/myostatin ratio and muscle fitness in older women: a randomized controlled trial.

This 12-week randomized controlled trial compared resistance exercise (RE), essential amino acid (EAA) supplementation, their combination, and control in 96 healthy women aged 65 years or older without insulin…

J Int Soc Sports NutrMar 21, 2026Read summary
Clinical ResearchGeriatrics

It's never too late: The impact of resistance training on strength and body composition in females across the lifespan - A systematic review and meta-analysis.

This systematic review and meta-analysis pooled 126 studies involving 4019 healthy women aged 18 years or older to assess resistance training effects on strength and body composition across the lifespan.

J Sci Med SportMar 18, 2026Read summary
Clinical ResearchGeriatrics

A Cluster-Randomized Clinical Trial of Silver Diamine Fluoride vs Atraumatic Restoration in Older Adults.

This multicenter cluster-randomized noninferiority trial compared biannual 38% silver diamine fluoride (SDF) with atraumatic restorative treatment (ART) plus fluoride varnish in adults aged 62 years or older living in…

J Dent ResMar 18, 2026Read summary
Clinical ResearchCardiology

Sarcopenia and Risk of Cardiovascular Events and Mortality: A Meta-analysis of Longitudinal Observational Studies.

This meta-analysis pooled longitudinal observational studies examining sarcopenia and related muscle traits in relation to cardiovascular outcomes.

Can J CardiolMar 14, 2026Read summary
Clinical ResearchOncology (Medical)

Effect of Narrative-Based Palliative Care on Psychological Stress, Quality of Life, and End-of-Life Acceptance in Elderly Terminal Cancer Patients and Their Families.

This single-center randomized controlled study evaluated narrative-based palliative care in 50 elderly patients with terminal cancer and their family caregivers.

Am SurgMar 13, 2026Read summary
Clinical ResearchGeriatrics

Process evaluation results of FEMuR III randomised controlled trial (RCT), a community-based rehabilitation following hip fracture surgery.

This mixed-methods process evaluation examined implementation of FEMuR, a community-based rehabilitation programme after hip fracture surgery, delivered across 13 sites within a randomised controlled trial.

Disabil RehabilMar 10, 2026Read summary
Clinical ResearchGeriatrics

Effect of assistive technology on the burden of caregivers to older adults: A systematic review.

This systematic review without meta-analysis examined whether assistive technologies reduce caregiving burden for older adults with cognitive impairments or disabilities.

Assist TechnolMar 10, 2026Read summary
Clinical ResearchGeriatrics

Efficacy of Progressive Exercise Snacking for Middle-Aged and Older Adults With Knee Osteoarthritis: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis assessed progressive exercise snacking (PES) for middle-aged and older adults with knee osteoarthritis. It included 18 randomized controlled trials involving 1,200 participants.

Arch Phys Med RehabilMar 7, 2026Read summary
Clinical ResearchGeriatrics

Preserving identity through caregiving: A systematic review and meta-synthesis of minority informal caregivers' experiences caring for older adults with neurological conditions.

This systematic review and thematic meta-synthesis examined how ethnic minority informal caregivers in Europe understand and navigate caring for older adults with neurological conditions.

Neuropsychol RehabilMar 4, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

A first-in-human Phase 1/1b randomized trial evaluating the safety and immunogenicity of a respiratory syncytial virus (RSV) virus-like particle subunit vaccine (IVX-121) in healthy young and older adults.

This randomized Phase 1/1b trial evaluated the safety and immunogenicity of IVX-121, an investigational RSV virus-like particle vaccine, in 90 healthy adults aged 18–45 years and 130 aged 60–75 years.

Hum Vaccin ImmunotherMar 3, 2026Read summary
Clinical ResearchGeriatrics

Therapeutic effects of Xianlinggubao capsules on knee function, inflammatory response, and bone metabolism in elderly patients with degenerative knee osteoarthritis.

This randomised controlled trial evaluated Xianlinggubao (XLGB) capsules added to celecoxib in 100 elderly patients with degenerative knee osteoarthritis.

Ann Hum BiolMar 3, 2026Read summary

February 20267

Clinical ResearchGeriatricsOpen access

Views and Experiences of People With Dementia, Informal Caregivers and Professionals on Eating and Drinking Difficulties: A Qualitative Systematic Review.

This qualitative systematic review examined how people with dementia, informal caregivers and professionals experience eating and drinking difficulties.

J Adv NursFeb 18, 2026Read summary
Clinical ResearchGeriatricsOpen access

Standards for Hospital Falls Prevention and Management: An International Comparative Analysis.

This international comparative analysis examined the content and quality of hospital standards addressing falls. Researchers searched databases, grey literature, and organisational websites for standards used across…

J Adv NursFeb 18, 2026Read summary
Clinical ResearchNeurologyOpen access

Mechanical thrombectomy for elderly stroke patients: An updated systematic review and meta-analysis of randomized clinical trials.

This systematic review and meta-analysis pooled randomized clinical trials comparing mechanical thrombectomy (MT) with standard medical management for acute ischemic stroke in patients over 70 years.

Neuroradiol JFeb 18, 2026Read summary
Clinical ResearchGeriatricsOpen access

Models of Care and Interventions to Improve Person-Centred Care for Older People in Long-Term Care Facilities: A Mixed Methods Systematic Review.

This mixed methods systematic review examined care models and interventions intended to improve person-centred care for older people in long-term care facilities.

J Adv NursFeb 15, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Comparison of opioid-free versus opioid-based total intravenous anaesthesia in elderly patients undergoing short-duration surgery: a randomized controlled trial.

This single-centre randomized controlled trial in China compared opioid-free total intravenous anaesthesia (OFA) with opioid-based total intravenous anaesthesia (OBA) in 400 patients aged 60 years or older undergoing…

Ann MedFeb 8, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Safety and Efficacy of Glucagon-Like Peptide-1 Receptor Agonists Use in Elderly People With Obesity-A Meta-Analysis.

This systematic review and meta-analysis compared GLP-1 receptor agonist safety and efficacy in adults aged 65 years or older with obesity versus younger adults, including people with or without type 2 diabetes.

Obesity (Silver Spring)Feb 4, 2026Read summary
Clinical ResearchGeriatrics

Methods and Measures Utilized in Older Adult Physical Activity Intervention Assessments: A Systematic Review.

This systematic review examined how physical activity outcomes were assessed in interventions involving older adults. The authors reviewed 45 articles identified through PubMed, CINAHL, and PsycInfo, considering study…

J Aging Phys ActFeb 4, 2026Read summary

January 20261

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