Trending archive
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433 articles
March 20267
Prophylactic Recombinant Human Thrombopoietin Prevents Cancer Therapy-Induced Thrombocytopenia During Concurrent Chemoradiation Therapy in Limited-Stage Small Cell Lung Cancer: A Prospective, Multicenter, Phase II Clinical Trial.
This prospective, multicenter, phase II trial assessed prophylactic recombinant human thrombopoietin (rhTPO) during concurrent chemoradiation in patients with limited-stage small cell lung cancer.
Severe Aplastic Anemia Concurrent with Lymphoplasmacytic Lymphoma/Waldenström's Macroglobulinemia.
A 79-year-old woman presented with progressive dyspnea. Bone marrow biopsy showed hypoplastic marrow containing abnormal lymphoid cells, and genetic analysis identified a MYD88 p.V204F mutation supporting…
Tranexamic acid in spontaneous intracerebral hemorrhage: an updated systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis of randomized controlled trials assessed tranexamic acid (TXA) for spontaneous intracerebral hemorrhage. Nine trials initially enrolled 3,124 patients.
Acute Promyelocytic Leukemia with t(11;17)(q23.2;q21.2) Treated with Haploidentical Transplantation Using Post-transplant Cyclophosphamide.
A 55-year-old man presented with acute promyelocytic leukemia (APL), diagnosed from its distinctive morphology. Subsequent cytogenetic testing identified t(11;17)(q23.2;q21.2), suggesting a ZBTB16::RARA fusion.
Severe Transfusion-refractory Cytopenia Mimicking Bone Marrow Failure in a Patient Living with HIV after Antiretroviral Therapy Interruption.
A 43-year-old woman living with HIV presented with life-threatening hematochezia and profound thrombocytopenia after interrupting antiretroviral therapy.
A Transfusion-transmitted Chronic Hepatitis E Virus Infection after Allogeneic Bone Marrow Transplantation with Viral Clearance Following Immunosuppression Tapering.
A 62-year-old woman with myelofibrosis developed liver dysfunction after allogeneic bone marrow transplantation. Testing showed anti-HEV IgA and HEV RNA, and matching viral RNA sequences in the transfusion donor and…
Post-transplant cyclophosphamide as graft-versus-host disease prophylaxis for matched related donor hematopoietic stem cell transplantation in acute leukemia: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed post-transplant cyclophosphamide (PTCy) for graft-versus-host disease (GVHD) prophylaxis in patients with acute leukemia undergoing matched related donor hematopoietic…
February 202617
Propofol and/or etomidate-induced immune thrombocytopenia: A case report.
A 62-year-old woman developed acute, severe thrombocytopenia after each of two separate general anesthesia procedures. The first episode occurred 14 days after laparoscopic renal cyst unroofing, with a platelet nadir of…
Kidney and Blood Pressure Outcomes in Children Surviving at Least 6 Months after Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis assessed late kidney and high blood pressure outcomes in children surviving at least 6 months after hematopoietic stem cell transplantation (HSCT).
The effect of occupational exposure to petrol on biochemical and hematological parameters: a review and meta-analysis.
This systematic review and meta-analysis assessed blood indices in fuel station workers occupationally exposed to petrol and diesel vapors, comparing exposed with unexposed groups.
Efficacy and safety of Ruxolitinib-based combination therapy in the patients with Myelofibrosis (MF): a systematic review and meta-analysis.
This systematic review and meta-analysis assessed the efficacy and safety of 13 ruxolitinib-based combination regimens for myelofibrosis, using 19 studies involving 1,088 patients.
Phase I trial of autologous regulatory T cells for immune aplastic anemia.
This phase I clinical trial evaluated autologous regulatory T-cell (Treg) therapy in six patients with immune aplastic anemia resistant or refractory to standard treatment.
Prognostic implications of myelodysplasia-related gene mutations in NPM1 -mutated acute myeloid leukemia: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed whether myelodysplasia-related gene (MRG) mutations affect prognosis in NPM1-mutated acute myeloid leukemia.
Secondary poor graft function after autologous stem cell transplantation in multiple myeloma: a case-based expert review and successful rescue with secondary autologous stem cell infusion.
A 59-year-old woman with IgG κ multiple myeloma initially achieved neutrophil and platelet engraftment after autologous hematopoietic stem-cell transplantation, but later developed recurrent transfusion-dependent…
Immune Dysregulation, Polyendocrinopathy and Enteropathy X-Linked Syndrome with Neonatal Onset: A Case Report.
A male infant born preterm at 30 weeks’ gestation developed enteropathy, eczema, eosinophilia, transfusion-dependent cytopenias, recurrent infections, and a desquamative rash.
Acute leukemia during pregnancy: a single center experience with 23 cases, 2012-2022 and literature review.
Acute Leukemia (AL) diagnosed during pregnancy is uncommon, and the management of AL complicated by pregnancy is a poorly studied area that faces a therapeutic dilemma.
Indirect treatment comparison of DVRd plus DR maintenance (PERSEUS study) versus DVTd or VTd with or without lenalidomide maintenance in transplant-eligible patients with previously untreated multiple myeloma.
This indirect treatment comparison assessed progression-free survival with DVRd induction and consolidation followed by daratumumab–lenalidomide maintenance (DR) versus VTd or DVTd regimens, with observation or…
Effect of fully immersive virtual reality on daily pain, functional mobility, and health-related quality of life in pediatric sickle cell disease: a single-blinded randomized clinical trial.
This single-blinded randomized controlled trial evaluated adjunctive fully immersive virtual reality (VR) in 40 children aged 8–18 years with sickle cell disease.
Switching patients with PNH from pegcetacoplan to iptacopan: a case series.
This case series describes three adults with paroxysmal nocturnal hemoglobinuria (PNH), including one man with aplastic anemia.
GNE-related thrombocytopenia (Thrombocytopenia-12) in a 3-month-old from a Middle Eastern background infant: a case report.
A 3-month-old infant of Middle Eastern background presented with severe thrombocytopenia (platelet count 6,000/μL) and neutropenia.
Management of an Allogeneic HSCT Recipient with an SICD during and after Total Body Irradiation.
A 19-year-old woman with acute myeloid leukemia who had received a subcutaneous implantable cardioverter defibrillator (SICD) was scheduled to undergo allogeneic hematopoietic stem cell transplantation (HSCT).
Warm Autoimmune Hemolytic Anemia Associated with Pancreatic Adenocarcinoma Showing Ectopic Expression of Band 3 Protein: A Case Report.
A 73-year-old woman with unresectable pancreatic adenocarcinoma developed warm autoimmune hemolytic anemia that was refractory to steroids. Prednisolone partially improved the anemia but did not control hemolysis.
Status Epilepticus as the Initial Manifestation of Follicular Lymphoma with Leptomeningeal Dissemination.
A 44-year-old man presented with meningoencephalitis and developed status epilepticus. Evaluation showed diffuse leptomeningeal dissemination of grade 1 follicular lymphoma, despite negative cerebrospinal fluid cytology.
Acute Lower Limb Arterial Occlusion Due to Malignant Lymphoma.
A 72-year-old man presented with acute pain and weakness in the left lower limb and was diagnosed with arterial occlusion. Examination of the thrombectomy specimen identified fibrin-associated diffuse large B-cell…
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