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441 articles
January 202614
Prevalence and incidence of post-intensive care syndrome among intensive care unit survivors: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis examined post-intensive care syndrome (PICS) among intensive care unit survivors, synthesising 34 cross-sectional and cohort studies with 6230 participants.
Emerging Role of Portable Accelerometers for Assessment of Gait Instability in Idiopathic Normal Pressure Hydrocephalus: A Systematic Review.
This PRISMA-guided systematic review assessed portable and smartphone-based accelerometers for measuring gait in idiopathic normal pressure hydrocephalus (iNPH).
Heliox ventilation promotes pulmonary circulation and cardiac function in elderly hypertensive patients: a randomized controlled trial.
This randomized controlled study compared heliox with conventional nitrogen–oxygen ventilation in 40 elderly hypertensive patients requiring invasive mechanical ventilation in an intensive care unit.
Reperfusion therapy for older patients with acute myocardial infarction and cardiogenic shock.
This systematic review and meta-analysis assessed reperfusion therapy versus non-reperfusion care in patients aged ≥75 years with acute myocardial infarction (AMI) and cardiogenic shock (CS).
Tai Chi modulating multimodal connectivity patterns and cognitive function in cerebral small vessel disease.
This randomized controlled trial examined whether Tai Chi affects cognition and brain connectivity in 51 patients with cerebral small vessel disease (CSVD).
Associations of Physical Activity Trajectories With Transitions Across Cognitive States: A Multinational Cohort Study.
This multinational cohort study examined whether physical activity (PA) trajectories were associated with transitions among no cognitive impairment, mild cognitive impairment (MCI), and dementia in data from HRS, ELSA…
Dialysis versus conservative kidney management in older adults: why one size does not fit all.
This narrative review synthesized observational, cohort, and systematic review evidence comparing dialysis with conservative kidney management (CKM) in adults aged ≥70 years with stage 4–5 chronic kidney disease.
Systematic Reviews of Psychosocial Interventions for Loneliness Among Older Adults in Community and Residential Care Settings: An Umbrella Review.
This umbrella review, conducted using Joanna Briggs Institute methodology, examined psychosocial interventions for loneliness among older adults in community and residential care settings.
Barriers and Facilitators for the Adaptation and Implementation of Cognitive Stimulation Therapy: A Systematic Review.
This systematic review examined barriers and facilitators encountered when adapting or implementing Cognitive Stimulation Therapy (CST) across countries.
Prolonged remission of dermatomyositis and autoantibody negativization following SARS-CoV-2 infection in an elderly patient.
An 80-year-old patient with dermatomyositis diagnosed in 2014 had initially responded to methotrexate. After severe SARS-CoV-2 infection with significant pulmonary involvement in March 2022, methotrexate was stopped.
Sustained salivary IgG but short-lived IgA responses following primary and booster MenACWY-TT vaccination in older adults.
This phase IV, open-label clinical trial assessed salivary antibody responses after primary MenACWY-TT vaccination in 216 adults aged 65–85 years; 100 participants received a booster one year later.
Intervention Without Borders - an Automated Self-Guided AI-Enhanced Psychoeducation Intervention for Dementia Caregivers: Parallel-Group Randomized Waitlist-Controlled Trial.
This parallel-group randomized waitlist-controlled trial evaluated PDC30, a fully automated, self-guided online psychoeducation intervention, in 274 caregivers from 43 countries.
Association between anaemia and osteoporosis: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis examined the association between anaemia and osteoporosis in 18 studies involving 861,540 participants.
Diagnostic and Surgical Challenges of Cauda Equina Syndrome in Elderly Patients with Diabetes Mellitus: A Systematic Review and Meta-Analysis of Clinical, Radiological, and Surgical Outcomes.
This systematic review and meta-analysis assessed diagnostic presentation, surgery, complications, and recovery in elderly patients with diabetes and confirmed cauda equina syndrome (CES).
December 20258
Efficacy of Brexpiprazole on Neuropsychiatric Symptoms and Impact on Caregivers: Pooled Neuropsychiatric Inventory (NPI) Analysis in Patients With Agitation Associated With Dementia due to Alzheimer's Disease.
This exploratory pooled analysis examined Neuropsychiatric Inventory (NPI) outcomes from two randomized, double-blind, placebo-controlled trials of brexpiprazole for agitation associated with Alzheimer’s disease…
Association of Preoperative Frailty and Postoperative Outcomes in Older Adults Undergoing Major Cardiac Procedures: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis examined preoperative frailty and postoperative outcomes in older adults undergoing major cardiac procedures.
The impact of the COVID-19 pandemic on osteoporotic fractures: a systematic review and meta-analysis.
This systematic review and meta-analysis examined observational or retrospective studies comparing osteoporotic fracture incidence in 2020 with 2019. Nine studies were included.
Impact of a physiotherapy-led low threshold exercise and protein supplementation intervention to optimise physical function and target frailty in people experiencing homelessness and addiction: The LEAP-II trial.
The LEAP-II trial was a pre-post intervention study at a day service centre, evaluating a physiotherapy-led, low-threshold exercise programme with protein supplementation among people experiencing homelessness and…
Beyond strength: dietary nitrate augments self-selected functional mobility after resistance training in middle-aged adults.
This 12-week randomized, double-blind, placebo-controlled pilot trial tested whether dietary nitrate added to resistance training improved gait and functional mobility in 28 healthy, inactive adults aged 56 ± 7 years.
Cognitive training effects are shaped more by individual brain dynamics than age-evidence from younger and older women.
This randomized controlled trial examined EEG functional connectivity during task switching in 39 younger women aged 18–25 and 40 older women aged 60–75.
Comparing rehabilitation with and without neuromuscular electrical stimulation in hospitalized older adults: Cognitive, functional, and acceptability outcomes from a pragmatic pilot study.
This pragmatic pilot comparative study examined whether adding neuromuscular electrical stimulation (NMES) to usual rehabilitation affected cognition, mobility, and acceptability among 29 hospitalized older adults (mean…
The Impact of Nutritional Status on Oral Health Outcomes and Management in Older Adults: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined associations between nutritional status and oral health in adults aged 75 years or older.
November 20252
Impact of Chewing Behavior Change on Cognition and Cerebral Hemodynamics.
This randomized controlled trial tested whether encouraging thorough chewing during meals affects cognition and cerebral hemodynamics in adults aged 65 years or older.
Association of the Timed Up and Go Test With Alzheimer's Disease: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined whether Timed Up and Go (TUG) performance is associated with mild cognitive impairment (MCI) or Alzheimer’s disease (AD) in adults.
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