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1022 articles
September 20268
Case Report: Post-Bomb Explosion Epilepsy.
This case report details two patients who developed post-traumatic epilepsy following exposure to explosive blasts in war zones.
Results From a Phase 2, Open-Label Study Evaluating the Safety, Tolerability, and Effect on Ataxia of GLM101 in Three Adult Patients With PMM2-CDG.
Phosphomannomutase 2 congenital disorder of glycosylation (PMM2-CDG) is a rare, autosomal recessive disease caused by PMM2 deficiency, which impairs conversion of mannose-6-phosphate into mannose-1-phosphate (M1P) and…
Efficacy and Durability of Repetitive Transcranial Magnetic Stimulation on Cognitive Function in Patients With Mild-to-Moderate Alzheimer's Disease: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the efficacy of repetitive transcranial magnetic stimulation (rTMS) on cognitive function in 143 patients with mild to moderate Alzheimer's disease.
Prevalence of unruptured intracranial aneurysms according to comorbidities, risk factors, country, and time period: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the prevalence of unruptured intracranial aneurysms (UIAs) across various comorbidities and risk factors, analyzing data from 316,131 participants.
Individual differences in brain dynamics across a social cognition network induced by cortico-cerebellar tDCS in adults with autism spectrum disorder (ASD).
This randomized controlled trial investigated the effects of cortico-cerebellar transcranial direct current stimulation (tDCS) on brain dynamics in 24 young adults with autism spectrum disorder (ASD).
Endovascular therapy for mild-to-moderate stroke due to basilar artery occlusion: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of endovascular therapy (EVT) for patients with mild-to-moderate stroke due to basilar artery occlusion (BAO) and NIHSS <10.
Plasma Biomarker Effects of Oral Valiltramiprosate/ALZ-801 in Early Alzheimer's Disease from Phase 3 and Phase 2 Trials: Analysis of Core Biomarkers and Correlations with Clinical and Neuroimaging Outcomes.
This study analyzed plasma biomarkers in APOE4 homozygotes with early Alzheimer's disease from Phase 3 and Phase 2 trials of valiltramiprosate/ALZ-801.
Effect of citicoline on cognitive function and functional recovery in patients with mild-to-moderate traumatic brain injury: a randomized placebo-controlled trial.
This randomized, placebo-controlled trial assessed the impact of citicoline on cognitive and functional recovery in 60 adults with mild-to-moderate traumatic brain injury (TBI).
August 202616
Systematic Review of Pharmacologic Treatment for Migraine Prevention in Adults: Report of the AAN Guidelines Subcommittee and the American Headache Society.
This systematic review evaluated pharmacologic treatments for migraine prevention in adults, analyzing 217 randomized controlled trials.
Treatment of multiple sclerosis with peptide-coupled red blood cells induces antigen-specific T regulatory cells.
This phase Ib clinical trial evaluated the safety and efficacy of peptide-coupled red blood cells (pcRBCs) in patients with multiple sclerosis (MS).
Association between Chagas disease and the occurrence of stroke: systematic review with meta-analysis.
This systematic review and meta-analysis examined the association between Chagas disease and stroke, including 7 studies. The analysis found that individuals with Chagas disease had a 1.92 times higher risk of stroke…
Neurofilament light chain dynamics following ischemic stroke and their modulation by transauricular vagus nerve stimulation.
This randomized controlled trial examined the dynamics of plasma neurofilament light chain (NfL) in 35 patients after acute ischemic stroke (AIS) and the effects of transauricular vagus nerve stimulation (taVNS).
IgG4-related disease involving facial, infraorbital, auriculotemporal and optic nerves: multinervous cranial involvement in an adult patient.
A man in his mid-40s presented with rapidly progressive orbital symptoms initially diagnosed as orbital cellulitis. Despite treatment, his condition deteriorated, leading to multiple cranial nerve involvement.
Hereditary neurodegenerative disorders with spastic-ataxic manifestations: genetic and clinical insights into previously reported variants.
Hereditary neurodegenerative disorders comprise a heterogeneous group of genetic conditions that affect the central and/or peripheral nervous system, often presenting with hallmark clinical features including ataxia…
The recurrent SACS gene p.Arg272His hotspot expands the neurodevelopmental and cognitive spectrum of ARSACS.
A 16-year-old Sicilian girl, born to consanguineous parents, presented with the classical symptoms of autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), including progressive cerebellar ataxia…
Transient Acute-onset Holmes-like Tremor After Cortical Stroke.
A 68-year-old man experienced acute right-sided facial and upper limb weakness and aphasia due to an isolated precentral cortical ischemic stroke.
Effects of strength and balance training on the structure of the aging brain.
This randomized controlled trial examined the effects of three months of strength and balance training on brain structure in 60 elderly adults aged 64-82.
Greater occipital nerve iatrogenic neuroma after cervical arthrodesis: high-frequency ultrasound findings and ultrasound-guided management.
A 45-year-old woman developed refractory bilateral occipital pain consistent with occipital neuralgia after cervical arthrodesis for disc herniation.
App-based self-administered biofeedback for the prevention of episodic migraine: A randomized controlled trial.
This randomized controlled trial evaluated the efficacy of an app-based biofeedback intervention for preventing episodic migraine in 279 adults.
APOE in subjective cognitive decline: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the prevalence of the APOE ε4 allele in individuals with subjective cognitive decline (SCD).
Ultrasound-Guided Lumbar Puncture:Experience in Two Difficult Cases.
This report details two challenging cases of lumbar puncture in patients with spinal deformities and prior lumbar surgery. Traditional anatomical landmarks were insufficient for accurate localization, necessitating the…
A single-cell meta-analysis evidences transposable element dysregulation in sex-based differences in Parkinson's disease.
This meta-analysis examined transposable element (TE) expression in Parkinson's disease (PD) using single-nucleus RNA-seq data from 66 donors.
Sex Differences in Treatment Effect of Adjunctive Intra-Arterial Urokinase After Successful Thrombectomy: A Post Hoc Secondary Analysis of the POST-UK Randomized Clinical Trial.
This post hoc secondary analysis of the multicenter POST-UK randomized clinical trial examined whether sex modified the effects of adjunct intra-arterial urokinase after successful endovascular thrombectomy.
Bridging the Gap: Translating Microemboli-Induced Spreading Depolarization Into Clinical Practice.
A 68-year-old woman experienced daily migraine aura episodes following mitral valve surgery. Transcranial Doppler revealed real-time microemboli in the posterior circulation during these episodes.
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