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359 articles

October 202624

Case ReportAnesthesiology

Bionic sleep therapy combined with multimodal management for chronic insomnia with alcohol withdrawal-related symptoms: A case report.

A 71-year-old man with more than 15 years of insomnia used 100 to 200 mL of Chinese baijiu nightly to sleep. Attempts to stop drinking brought worsening insomnia, restlessness, palpitations, sweating, and intense…

Medicine (Baltimore)Oct 9, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Ketamine and esketamine during breastfeeding: a systematic review of human pharmacokinetic, infant and lactation outcomes.

This systematic review synthesised human evidence on ketamine and esketamine transfer into breast milk, infant exposure and outcomes, and breastfeeding outcomes after postpartum exposure.

Eur J Clin PharmacolOct 9, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Efficacy and safety of intraoperative red blood cell salvage transfusion for spinal deformity surgery: a systematic review and meta-analysis.

This systematic review and meta-analysis pooled 22 observational studies of spinal deformity surgery, including 2,977 patients treated with intraoperative cell salvage (ICS) or without it.

Neurosurg RevOct 9, 2026Read summary
Case ReportUrology

Rhabdomyolysis Following Robot-Assisted Radical Prostatectomy.

A 66-year-old man with obesity, insulin-dependent diabetes, and multiple comorbidities underwent robot-assisted radical prostatectomy for cT3a cN1 prostate cancer, with approximately 4 hours of console time.

J Vis ExpOct 9, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Effects of Sodium Bicarbonate Ringer's Solution versus Lactate Ringer's Solution on Emergence Time in Patients Undergoing Supratentorial Tumor Resection: A Randomized Controlled Trial.

This randomized controlled trial compared intraoperative sodium bicarbonate Ringer’s solution (BRS) with lactated Ringer’s solution (LRS) in patients undergoing elective supratentorial tumor resection.

Drug Des Devel TherOct 9, 2026Read summary
Case ReportAnesthesiologyOpen access

Ilioinguinal-Transversus Abdominis Plane (I-TAP) Block with Liposomal Bupivacaine for Analgesia After Cesarean Delivery: A Randomized Controlled Trial.

Cesarean delivery is frequently associated with suboptimal postoperative analgesia. While PROSPECT guidelines recommend transversus abdominis plane (TAP) block for post-cesarean analgesia, conventional TAP block may…

Drug Des Devel TherOct 8, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Effect of Anterior Quadratus Lumborum Block at the Lateral Supra-Arcuate Ligament Combined with Esketamine on the Quality of Postoperative Recovery After Laparoscopic Radical Surgery for Elderly Patients with Colorectal Cancer: A Randomized Controlled Trial.

This single-centre, randomized, placebo-controlled trial evaluated anterior quadratus lumborum block at the lateral supra-arcuate ligament (QLB-LSAL), low-dose esketamine, or their combination in patients aged 60 years…

Drug Des Devel TherOct 8, 2026Read summary
Clinical ResearchAnesthesiology

Effects of remimazolam versus propofol on cerebral oxygenation in elderly patients undergoing prone spine surgery: study protocol for a randomised controlled trial.

This article describes the protocol for a prospective, single-centre randomised controlled trial comparing remimazolam with propofol-based total intravenous anaesthesia in elderly patients undergoing elective thoracic…

BMJ OpenOct 7, 2026Read summary
Clinical ResearchAnesthesiology

Daily sedation interruption versus no daily sedation interruption for critically ill adults and children requiring invasive mechanical ventilation.

This updated Cochrane systematic review and meta-analysis assessed daily sedation interruption (DSI) versus sedation strategies without interruption in critically ill adults and children receiving invasive mechanical…

Cochrane Database Syst RevOct 7, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Survival outcomes following total intravenous versus volatile anesthesia in esophagogastric cancer surgery: a systematic review and meta-analysis.

This systematic review and meta-analysis compared total intravenous anesthesia (TIVA) with volatile anesthesia in adults undergoing curative surgery for esophageal or gastric cancer.

Langenbecks Arch SurgOct 7, 2026Read summary
Case ReportAnesthesiologyOpen access

Effect of a Single Subanesthetic Dose of Esketamine on Gastrointestinal Recovery After Laparoscopic Colorectal Cancer Surgery: A Randomized, Outcome-Assessor-Blinded, Placebo-Controlled Trial.

Postoperative gastrointestinal dysfunction (POGD) and Postoperative gastrointestinal intolerance (POGI) remain a critical challenge in abdominal surgery, particularly for colorectal cancer patients undergoing…

Drug Des Devel TherOct 7, 2026Read case
Clinical ResearchPulmonology

Digital Twin-Assisted Risk Disclosure in Adults Undergoing Elective Bronchoscopy: Multicenter Randomized Controlled Trial.

This multicenter randomized controlled trial evaluated the impact of digital twin-assisted risk disclosure on prebronchoscopy anxiety and postbronchoscopy satisfaction in adults undergoing elective bronchoscopy.

J Med Internet ResOct 6, 2026Read summary
Case ReportPediatrics

Comprehensive dental management of odontogenic infection and ankyloglossia under general anaesthesia in a medically complex child with intellectual disability.

A middle childhood child with moderate intellectual disability presented with pain and swelling in the right posterior mandibular area.

BMJ Case RepOct 5, 2026Read case
Clinical ResearchUrology

Caudal versus penile block and urethrocutaneous fistula formation following hypospadias repair in children <2 years: a multicenter randomized clinical trial.

This multicenter randomized controlled trial evaluated the incidence of urethrocutaneous fistula (UCF) formation in children under 2 years undergoing hypospadias repair with either caudal or penile block.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchAnesthesiology

Clinical utility of randomized controlled trials of regional anesthesia for lower-extremity surgery: a systematic review.

This systematic review evaluated the clinical utility and transparency of randomized controlled trials (RCTs) on regional anesthesia (RA) for lower-extremity surgeries.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchAnesthesiology

Assessing the completeness of safety reporting in clinical trials of regional anesthesia interventions: a registry-publication comparison systematic review.

This systematic review evaluated the completeness of adverse event (AE) reporting in interventional regional anesthesia trials registered on ClinicalTrials.gov and their corresponding publications.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchPlastic Surgery

Feeding following cleft palate surgery: a prospective randomized clinical trial comparing suprazygomatic maxillary nerve block and greater palatine nerve block.

This randomized controlled trial evaluated the effectiveness of suprazygomatic maxillary nerve blocks (SZMNB) versus greater palatine nerve blocks (GPNB) in children aged 1-10 undergoing cleft palate surgery.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchAnesthesiology

Impact of opioid-free general anesthesia with locoregional blocks during breast cancer surgery on systemic inflammatory response: results from a randomized controlled trial.

This randomized controlled trial evaluated the effects of opioid-free general anesthesia with locoregional blocks (OfGA) versus traditional opioid-based general anesthesia (GA) on postoperative inflammation in breast…

Reg Anesth Pain MedOct 5, 2026Read summary
Case ReportAnesthesiologyOpen access

Remimazolam ED95 for Preoperative Sedation in Children with Obstructive Sleep Apnea, with Obesity or a Reference-Range BMI: A Biased-Coin Dose-Finding Study.

Obesity may alter total-body-weight dosing of remimazolam, whereas obstructive sleep apnea narrows the respiratory safety margin.

Drug Des Devel TherOct 5, 2026Read case
Clinical ResearchAnesthesiology

Repeated remimazolam sedation for interstitial brachytherapy in cervical cancer: a randomized controlled trial.

This randomized controlled trial evaluated the safety and efficacy of repeated remimazolam sedation compared to propofol in 100 patients with cervical cancer undergoing interstitial brachytherapy.

Ann MedOct 4, 2026Read summary
Case ReportAnesthesiology

Perioperative adrenal insufficiency presenting as refractory hypotension: A CARE-compliant article.

A 77-year-old woman undergoing lumbar fusion surgery experienced severe hypotension that did not respond to fluid resuscitation or vasopressors.

Medicine (Baltimore)Oct 2, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Effects of stellate ganglion block on postoperative sleep disturbance: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effects of stellate ganglion block (SGB) on postoperative sleep disturbance in 734 participants from 10 randomized controlled trials.

Sleep BreathOct 2, 2026Read summary
Case ReportAnesthesiologyOpen access

Comparisons in Analgesic Effects Between Ultrasound-Guided Erector Spinae Plane Block and Ultrasound-Guided Modified Intercostal Nerve Block in Modified Radical Mastectomy: A Randomized Controlled Trial.

Postoperative acute pain is a common challenge after breast cancer surgery. This randomized controlled trial compared the analgesic effects of ultrasound-guided erector spinae plane block (ESPB) and modified intercostal…

Drug Des Devel TherOct 2, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Intraoperative Dexmedetomidine and Postoperative Delirium After Head and Neck Cancer Surgery with Free-Flap Reconstruction: A Secondary Analysis of a Randomized Placebo-Controlled Trial.

This delirium-focused secondary analysis of a single-centre, randomized, double-blind, placebo-controlled trial examined adults undergoing elective head and neck cancer surgery with free-flap reconstruction.

Drug Des Devel TherOct 2, 2026Read summary

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