Trending archive
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1821 articles
September 202624
A qualitative study of cancer survivors' exercise behaviour 4 months after a telerehabilitation program.
This qualitative study, part of a randomized controlled trial, examined the exercise behaviors of 17 cancer survivors four months after completing a telerehabilitation program.
Osimertinib With or Without Chemotherapy in Advanced Non-Small Cell Lung Cancer With EGFR and Concurrent TP53 Mutations: A Randomized Clinical Trial.
This phase 3 randomized clinical trial evaluated the efficacy and safety of osimertinib combined with chemotherapy versus osimertinib alone in 294 patients with advanced non-small cell lung cancer (NSCLC) harboring…
Frontline therapies for adult patients with newly diagnosed Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia: a systematic literature review.
This systematic review evaluated 96 studies on frontline therapies for adults with Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia (B-ALL).
Incidental Glioblastoma Multiforme Detected on 18 F-DCFPyL PET/CT Prostate Cancer Staging.
A 77-year-old man was referred for an 18 F-DCFPyl PET/CT scan for staging of prostate cancer. The scan demonstrated an incidental intensely avid brain lesion in the right frontal lobe.
Readmission in patients with hematologic malignancies: A systematic review and meta-analysis.
This systematic review and meta-analysis quantified readmission rates across follow-up windows in patients with hematologic malignancies and assessed associated factors. It included 104 studies.
Primary Cerebral Pleomorphic-Myxoid Sarcoma With Many Hyaline Globules.
A 59-year-old man presented with a primary sarcoma in the right temporal lobe, following a history of pituitary tumor resection and radiotherapy 40 years prior.
Safety and efficacy of Meridian sinew tuina (MST) for post-surgical upper limb lymphedema: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the safety and efficacy of Meridian Sinew Tuina (MST) for post-surgical upper limb lymphedema in breast cancer patients.
Evidence Gap in Managing Lateral Pelvic Lymph Nodes in Rectal Cancer: a Systematic Review of Radiation Boost Strategies.
This systematic review assessed radiation dose escalation to radiologically suspicious lateral pelvic lymph nodes (LPLNs) during neoadjuvant chemoradiotherapy for locally advanced rectal cancer.
Testicular aggressive B-cell lymphoma with plasmablastic morphology harboring concurrent IGH::MYC and IGH::BCL2 rearrangements.
A 66-year-old immunocompetent man presented with a 5 cm left testicular mass. Histological analysis showed a diffuse proliferation of large atypical lymphoid cells with plasmablastic morphology.
The role of particle therapy in the treatment of locally recurrent rectal cancer: a systematic review.
This systematic review evaluated the role of particle therapy in treating locally recurrent rectal cancer, particularly in patients with unresectable or inoperable cases.
Transcriptomic analysis of a phase 1 trial for intraperitoneal monocytes plus IFNs in ovarian cancer reveals support and recruitment of cell-mediated immunity.
This phase 1 trial investigated the effects of intraperitoneal autologous monocytes with interferons (AMIGA) in women with recurrent, platinum-resistant ovarian cancer.
Phase 1/1b open-label, first-in-human study of HER2×CD3×CD28 trispecific T-cell engager (SAR443216) in participants with R/R HER2-expressing solid tumors.
This Phase 1/1b open-label study evaluated SAR443216, a trispecific T-cell engager, in 40 participants with relapsed/refractory HER2-expressing solid tumors.
Intravascular large B-cell lymphoma with reversible central hypopituitarism.
A woman in her late 60s presented with fever and general fatigue. Investigations showed bicytopenia, splenomegaly, and central hypothyroidism.
How prevalent is fear of cancer recurrence beyond 5 years: a systematic review of validated assessments across tumour types.
This systematic review examined the prevalence of fear of cancer recurrence (FCR) in survivors beyond 5 years across various tumor types.
Management of oral stomatitis associated with BRAFi-MEKi therapy using intralesional corticosteroid and local anesthetic: a case report.
A 66-year-old woman with a history of choroidal melanoma developed a fibrinopurulent ulcer on the tongue after starting dabrafenib-trametinib therapy for tumor recurrence.
Induction and extended consolidation with daratumumab, cyclophosphamide, bortezomib, lenalidomide, and dexamethasone in patients with high-risk multiple myeloma (OPTIMUM/MUKnine): 5-year follow-up of a multicentre, externally controlled, phase 2 trial.
The OPTIMUM trial, a multicentre, phase 2 study, evaluated the effects of intensified induction and extended consolidation therapy in 107 patients with high-risk multiple myeloma.
Chemotherapy with or without pembrolizumab followed by maintenance pembrolizumab with or without olaparib as first-line treatment of patients with advanced BRCA non-mutated epithelial ovarian cancer (ENGOT-OV43/GOG-3036/KEYLYNK-001): a randomised, double-blind, placebo-controlled, phase 3 trial.
This phase 3 randomized trial evaluated the efficacy and safety of pembrolizumab plus chemotherapy followed by pembrolizumab plus olaparib maintenance in 1367 women with advanced BRCA non-mutated epithelial ovarian…
Extramedullary T-Lymphoblastic Blast Crisis in Chronic Myeloid Leukaemia: A Unique Cytologic Diagnosis Confirmed by Flow Cytometry.
A 40-year-old man presented with generalized lymphadenopathy, hepatosplenomegaly, anemia, and marked leukocytosis. Bone marrow examination indicated chronic phase chronic myeloid leukaemia (CML) with confirmed BCR::ABL1…
Extraperitoneal Single-Port Robotic-Assisted Radical Cystectomy with Orthotopic Ne-obladder: Technique and Surgical Considerations.
Radical cystectomy (RC) is the standard therapy for muscle-invasive bladder cancer (MIBC) and refractory high-risk non-muscle-invasive bladder cancer (1-3).
Primary cutaneous epithelioid hemangioendothelioma of the temporal region: a case report.
A 70-year-old female presented with a progressively ulcerated plaque on her left temple. Histopathological analysis confirmed primary cutaneous epithelioid hemangioendothelioma (EHE) through characteristic features and…
Locoregional recurrence of triple-negative breast cancer with low tumor-infiltrating lymphocytes: a case report.
A 49-year-old postmenopausal woman with triple-negative breast cancer (TNBC) experienced an unusual locoregional recurrence three months after a Patey mastectomy.
Laparoscopic Resection of Vaginal Cuff Recurrence Following Surgery for Endometrial Cancer.
Vaginal cuff recurrence of endometrial cancer is generally managed with radiotherapy, and surgical reports are scarce. We report a laparoscopic resection technique for isolated vaginal cuff recurrence.
Successful Engraftment Following Second Cord Blood Transplantation After Graft Failure in a Child With Relapsed B-ALL.
A 9-year-old boy with relapsed B-cell precursor acute lymphoblastic leukemia experienced primary graft failure after his first umbilical cord blood transplantation due to low CD34-positive cell dose and significant HLA…
Adult-Onset Langerhans Cell Histiocytosis With Calvarial and Hypothalamic Involvement: Two Cases.
This report details two cases of adult-onset Langerhans cell histiocytosis (LCH). The first case involved a 36-year-old woman with a solitary osteolytic lesion in the calvarium, treated with surgical resection and…
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