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408 articles

October 202624

Clinical ResearchPreventive Medicine / Public Health

A Single Exercise Session Elicits a Transient Kynurenine Metabolic Signature in Health and Disease: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined acute changes in circulating tryptophan (TRP) and kynurenine-pathway metabolites after a single exercise session.

FASEB JOct 14, 2026Read summary
Clinical ResearchCardiologyOpen access

Ramadan Fasting in Chronic Heart Failure: A Systematic Review.

This systematic review assessed clinical studies of Ramadan fasting in people with chronic heart failure. Searches of PubMed, Scopus, and Web of Science identified seven eligible studies from 137 records; most were…

Curr Cardiol RepOct 14, 2026Read summary
Clinical ResearchPediatrics

Cost comparison of the ShangRing device versus Mogen clamp for early infant male circumcision in Sub-Saharan Africa.

This cost comparison alongside a randomized controlled trial assessed early infant male circumcision using the ShangRing (SR) versus the Mogen clamp (MoC) among infants aged 0–60 days in Kenya, Tanzania, and Uganda.

PLoS OneOct 13, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Menstrual health challenges and associated barriers among tribal adolescent girls in India: A systematic review.

This systematic review synthesised quantitative, qualitative and mixed-methods research on menstrual health among tribal adolescent girls in India.

PLoS OneOct 12, 2026Read summary
Clinical ResearchPediatrics

Home visits following hospital discharge for families with preterm and low-birthweight infants.

This Cochrane systematic review and meta-analysis assessed randomised trials of home visits after discharge for families of preterm or low-birthweight infants.

Cochrane Database Syst RevOct 12, 2026Read summary
Case ReportGastroenterologyOpen access

Multifactorial Contributors to Diagnostic Delay in a High-Risk Patient with Hepatocellular Carcinoma: A Case Report with Clinical Lessons.

A 45-year-old Chinese man with chronic hepatitis B, type 2 diabetes, and a family history of primary liver cancer (PLC) was at high risk but had no regular PLC surveillance for three years.

Int Med Case Rep JOct 12, 2026Read case
Clinical ResearchCardiology

Pilot Randomized Trial of 2 Food Purchasing Interventions in Individuals With Hypertension in New Orleans: An American Heart Association Food Is Medicine Initiative.

This randomized pilot trial compared online and in-store food vouchers among 98 people with uncontrolled hypertension in New Orleans.

J Am Heart AssocOct 10, 2026Read summary
Clinical ResearchVascular Surgery

Omega-6 Polyunsaturated Fatty Acids and Peripheral Artery Disease: An Individual Participant-Level Analysis of 9 International Prospective Studies.

This multicohort individual participant-level analysis and meta-analysis examined baseline omega-6 polyunsaturated fatty acids and incident peripheral artery disease (PAD) among 137,704 participants without clinical PAD…

J Am Heart AssocOct 10, 2026Read summary
Clinical ResearchEndocrinology

Time-restricted feeding with resistance training is not superior to conventional feeding for body composition and muscle strength: a systematic review and meta-analysis.

This systematic review and meta-analysis examined time-restricted feeding (TRF) versus conventional diets in healthy adults aged 18 or older undertaking resistance training.

An Acad Bras CiencOct 9, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Effect of amaranth flatbread on maternal anthropometry during pregnancy: Evidence from a cluster-randomized controlled trial in Southern Ethiopia.

This parallel-group, cluster-randomized controlled trial assessed daily amaranth-chickpea flatbread in pregnant women with mild-to-moderate anemia in Southern Ethiopia.

PLoS OneOct 8, 2026Read summary
Clinical ResearchGeriatrics

Adverse childhood experiences, cognitive outcomes, and frailty in older adults: a systematic review and meta-analysis.

This systematic review and meta-analysis examined associations between adverse childhood experiences (ACEs) and frailty or cognitive outcomes in middle-aged and older adults.

GerontologistOct 8, 2026Read summary
Clinical ResearchInfectious Diseases

A Phase 1/2 Dose-Ranging Safety and Immunogenicity Study of mRNA-Based Candidate Pandemic Influenza Vaccines in Healthy Adults.

This randomised phase 1/2 dose-ranging study evaluated the safety, reactogenicity, and immunogenicity of mRNA-1018 pandemic influenza vaccine candidates in healthy adults.

Clin Infect DisOct 7, 2026Read summary
Clinical ResearchRheumatology

Prospective controlled study of the recombinant zoster vaccine in autoimmune rheumatic disease: robust seroconversion despite intravenous cyclophosphamide.

This subanalysis of a prospective, randomized, placebo-controlled trial assessed recombinant zoster vaccine (RZV) responses in patients with autoimmune rheumatic disease receiving intravenous cyclophosphamide (IVCYC)…

VaccineOct 7, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Adult diagnostic reference levels in computed tomography: A systematic review and analysis of regional variability.

This systematic review examined adult computed tomography diagnostic reference levels (DRLs) across regions and examination types.

Eur J RadiolOct 7, 2026Read summary
Clinical ResearchCardiology

Acute effects of volume-matched isometric exercise intensity on vascular function and autonomic regulation in men with elevated blood pressure.

This randomized controlled trial examined the acute effects of high-intensity isometric exercise (HIIE) versus low-intensity isometric exercise (LIIE) on cardiovascular function in 17 men with elevated blood pressure.

Clin Physiol Funct ImagingOct 6, 2026Read summary
Clinical ResearchPediatricsOpen access

Iron or Multiple Micronutrient Powder Supplements With Malaria Chemoprevention in Rural Malawian Children: The IRMA Randomized Clinical Trial.

This randomized clinical trial evaluated the effects of iron supplements combined with malaria chemoprevention on cognitive outcomes in 6-month-old infants in rural Malawi.

JAMAOct 6, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Effectiveness of Immersive and Embodied Enhancement via "Virtual Reality" on the Sustainability of Hand Hygiene Compliance:Protocol for a Randomized Controlled Trial of a School-Based Training Program.

This protocol describes a three-arm randomized controlled trial evaluating customized virtual reality (VR) handwashing education among secondary school students in Hong Kong.

JMIR Res ProtocOct 6, 2026Read summary
Clinical ResearchFamily Medicine

Changes in health literacy following participation in a multidisciplinary primary care intervention for people with chronic pain: a longitudinal cohort study.

This longitudinal cohort study examined changes in health literacy among 43 people with chronic non-cancer pain who completed a personalized, multidisciplinary primary care pain-management intervention.

Scand J PainOct 6, 2026Read summary
Clinical ResearchPsychiatry

Cannabis use and subsequent onset of manic symptoms and bipolar disorder: A systematic review and meta-analysis.

This registered systematic review and meta-analysis examined longitudinal observational studies of people without prior bipolar disorder, comparing those exposed and unexposed to cannabis.

J Affect DisordOct 6, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Maternal circulating cytokine and chemokine levels during pregnancy and risk of autism spectrum disorder in offspring: A systematic review and meta-analysis.

This systematic review and meta-analysis examined whether maternal blood cytokine and chemokine levels during pregnancy were associated with autism in offspring, drawing on seven human observational studies.

Neurosci Biobehav RevOct 6, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Fluid balance during hot-dry and warm-humid heat stress while adhering to occupational hydration recommendations.

This randomized controlled trial assessed fluid balance in 20 healthy adults during moderate-intensity work in hot-dry (HD) and warm-humid (WH) environments while following NIOSH hydration recommendations.

Ann Work Expo HealthOct 5, 2026Read summary
Clinical ResearchGeriatrics

Vitamin D Supplementation and Mortality in the Elderly: A Review of a Meta-Analysis of Randomized Controlled Trials Using the REB Method.

This meta-analysis reviewed 25 randomized controlled trials (RCTs) to evaluate the impact of vitamin D supplementation on mortality in individuals aged 75 and older.

Fundam Clin PharmacolOct 3, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Determinants of delayed antenatal visit attendance in rural Burkina Faso: a cross-sectional study.

This cross-sectional study assessed delayed antenatal care (ANC) attendance among pregnant women in rural Burkina Faso. Out of 2480 women with data, 90.6% attended their first ANC visit after the 14th week of gestation.

BMC Pregnancy ChildbirthOct 3, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Effectiveness of a nurse-led telephonic brief intervention to reduce risky alcohol use among women in primary care in Brazil: a randomized controlled trial.

This randomized controlled trial evaluated a nurse-led telephonic brief intervention aimed at reducing risky alcohol use among 151 women in primary care in São Paulo, Brazil.

Arch Womens Ment HealthOct 2, 2026Read summary

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