Trending archive
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793 articles
April 20263
A randomized, open-label, phase 2a study to assess the safety, pharmacodynamics, and pharmacokinetics of YAQ007 versus rifaximin in cirrhosis.
This randomized, open-label, multicenter phase 2a study compared three oral YAQ007 regimens with rifaximin in 48 patients with cirrhosis and a history of overt hepatic encephalopathy.
Interventions for Increasing Colorectal Cancer Screening Uptake: A Systematic Review and Network Meta-Analysis.
This systematic review and network meta-analysis compared eight strategies for increasing colorectal cancer screening uptake across 76 randomized clinical trials.
Histomorphological Features of a Liver Explant From an Adult With Arthrogryposis-Renal Dysfunction-Cholestasis Syndrome: A Case Report and Literature Review.
A woman in her early twenties with genetically confirmed arthrogryposis-renal dysfunction-cholestasis syndrome, carrying compound heterozygous VPS33B mutations, developed progressive liver dysfunction and…
March 202621
Collision Tumor in the Stomach: Tubular Gastric Adenocarcinoma With Metastatic Adrenocortical Carcinoma-A Rare Encounter on an Endoscopic Biopsy.
A gastric lesion was found to contain two distinct malignancies: primary tubular gastric adenocarcinoma and metastatic adrenocortical carcinoma.
Colorectal neoplasia-specific amino acid profiles and their diagnostic potential: a systematic review.
This systematic review assessed amino acid alterations in colorectal cancer (CRC) and advanced precursors, and their potential as non-invasive diagnostic biomarkers.
Secondary changes in the peripheral liver due to kaposiform haemangioendothelioma in the hepatic hilum: a report of two transplant cases.
Two patients underwent liver transplantation for liver failure associated with clinically unsuspected kaposiform haemangioendothelioma (KHE) at the hepatic hilum.
Comparative efficacy and safety of bi-flanged metal stents versus lumen-apposing metal stents for endoscopic drainage of pancreatic fluid collections: a systematic review and meta-analysis.
This systematic review and meta-analysis compared bi-flanged metal stents (BFMS) with lumen-apposing metal stents (LAMS) for endoscopic ultrasound-guided drainage of pancreatic fluid collections.
Efficacy and Safety of Etrasimod in Moderate-To-Severe Ulcerative Colitis: A GRADE-Based Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This GRADE-based systematic review and meta-analysis pooled four randomized controlled trials comparing etrasimod with placebo in 1,239 adults with moderately to severely active ulcerative colitis.
Necrotizing Enterocolitis as a Rare Complication of Severe RSV Bronchiolitis in a Term Neonate: A Case Report With Narrative Review.
A previously healthy, full-term 24-day-old neonate was admitted with severe respiratory syncytial virus (RSV) bronchiolitis.
Endoscopic submucosal dissection for locally recurrent gastric neoplasia following endoscopic resection: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis assessed salvage endoscopic submucosal dissection (ESD) for locally recurrent gastric neoplasia at or near a prior endoscopic resection scar, where fibrosis can…
Recurrent pancreatitis and atypical hemolytic uremic syndrome (aHUS): an unusual presentation in childhood.
A 10-year-old boy presented with abdominal pain, vomiting, oliguria, and epigastric tenderness during acute pancreatitis accompanied by atypical hemolytic uremic syndrome (aHUS).
Positive conversion of latent tuberculosis screening in patients with inflammatory bowel disease on antitumor necrosis factor alpha drugs: a systematic review and meta-analysis.
This systematic review and single-arm meta-analysis assessed positive conversion on latent tuberculosis (TB) screening among patients with inflammatory bowel disease (IBD) receiving anti-TNF therapy after a negative…
Effect of probiotic and synbiotic administration on the nutritional status of hemodialysis patients: a randomized-controlled trial.
This single-blind randomized controlled trial assessed probiotic and synbiotic supplementation in 60 maintenance hemodialysis patients over 24 weeks.
Cost-effectiveness of treatment and care of patients with gastrointestinal inflammatory diseases: a systematic review.
This PRISMA-guided systematic review descriptively synthesized 18 studies published between 2013 and 2024 evaluating treatment cost-effectiveness in Crohn’s disease and/or ulcerative colitis.
Antibiotic Use During Gastrointestinal Infections Increases the Risk of Developing Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined new irritable bowel syndrome (IBS) diagnoses among people with documented antibiotic exposure compared with unexposed controls.
Beyond rejection risk: Identifying ideal candidates for pretransplant immune checkpoint inhibitors for HCC.
This systematic review assessed immune checkpoint inhibitors (ICIs) used as bridging or downstaging therapy before liver transplantation for hepatocellular carcinoma.
Combined Hepatocellular-cholangiocarcinoma Patient Treated with Durvalumab Plus Gemcitabine and Cisplatin.
A 55-year-old man with lower abdominal pain and diarrhea was referred to our hospital. Computed tomography (CT) revealed a hypovascular liver tumor, lymph node/bone metastases, and peritoneal dissemination.
Relative Effects of Time-Restricted Eating, Energy-Restricted Eating, and Unrestricted Eating on Eating Patterns and Dietary Intake: Results From a Randomized Controlled Trial.
This secondary analysis of a randomized controlled trial examined eating patterns and dietary intake among adults with obesity assigned to time-restricted eating (TRE), energy-restricted eating (ER), or unrestricted…
ASSOCIATION BETWEEN GASTROESOPHAGEAL REFLUX DISEASE AND PEPTIC ULCER IN ADULTS AND THE DEVELOPMENT OF PERIODONTAL CHANGES AND DENTAL CARIES: SYSTEMATIC REVIEW AND META-ANALYSIS.
This systematic review and meta-analysis examined associations between gastroesophageal reflux disease (GERD) or peptic ulcer and dental caries or periodontal disease.
Clinical Efficacy Evaluation of a Continuous Glucose Monitoring-Guided Forecasting Algorithm to Mitigate Postbariatric Hypoglycemia: A Randomized Controlled Trial.
This randomized controlled trial evaluated whether a continuous glucose monitoring (CGM)-guided forecasting algorithm could reduce postbariatric hypoglycemia during a standardized meal test in 59 people after Roux-en-Y…
Longitudinal assessment of the circulating cytokine profile of severe alcohol-associated hepatitis.
This longitudinal biomarker analysis used samples from 89 patients with severe alcohol-associated hepatitis (MELD≥20) enrolled in a multicenter, double-blind randomized trial comparing anakinra-based treatment with…
Changes in quality of life in colorectal cancer screening: A multicentre trial in populations in China.
This multicentre randomised trial assessed quality of life among 19,373 participants in China allocated to one-time colonoscopy, annual faecal immunochemical testing (FIT) with colonoscopy after a positive result, or…
Mirikizumab Long-Term Efficacy and Safety in Patients With Crohn's Disease: Results From the VIVID-2 Open-Label Extension Trial.
This interim analysis of the VIVID-2 open-label extension followed patients with moderately to severely active Crohn’s disease who had received mirikizumab in the VIVID-1 randomized trial and continued treatment for up…
Not all small bowel pneumatosis is ischaemia: a case-based systematic review of non-ischaemic causes.
A 74-year-old man developed small-bowel pneumatosis after ileostomy reversal. Computed tomography initially raised concern for bowel ischaemia, but he had no clinical or biochemical evidence of sepsis.
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