Trending archive
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755 articles
January 20265
Association between anaemia and osteoporosis: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis examined the association between anaemia and osteoporosis in 18 studies involving 861,540 participants.
Effect of monotherapeutic caloric restriction diet on cardiometabolic parameters in adults with overweight or obesity: Insights from meta-analyses of randomized controlled trials.
This meta-analysis of 17 randomized controlled trials examined monotherapeutic caloric restriction diets versus usual diets in 1066 adults at high cardiovascular risk; all trial populations had a mean baseline BMI ≥30…
AI-Assisted Sonography for the Diagnosis of Thyroid Nodules.
This systematic review assessed the diagnostic performance and clinical utility of AI-assisted sonography for thyroid nodules.
Thyroid Cancer Management in Contemporary Practice: A Systematic Review and Meta-Analysis of Diagnostic Pathways, Surgical Strategies, Airway Challenges, and Mediastinal Extension.
This systematic review and meta-analysis synthesized 11 primary studies published between 2021 and 2026, covering 6,142 patients with thyroid cancer and focusing on diagnostic performance, airway management, surgical…
Albuminuria as a Clinical Marker of Subclinical Myocardial Dysfunction in Diabetes: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis examined whether albuminuria is associated with echocardiographic evidence of subclinical myocardial dysfunction in adults with diabetes.
December 20254
Effects of a slowly fermentable fiber mixture against the background of a high-protein diet on insulin sensitivity and metabolic health in individuals with overweight: a randomized, placebo-controlled trial.
This 12-week randomized, placebo-controlled trial tested daily potato fiber and sugar beet pectin against maltodextrin in adults with overweight or obesity consuming a high-protein diet.
Treatment preference for once-weekly versus once-daily DPP-4 inhibitors in patients with type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis of randomized controlled trials compared once-weekly with once-daily DPP-4 inhibitors in people with type 2 diabetes.
Global epidemiology of diabetes and prediabetes in lean or non-obese patients with NAFLD: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis estimated the global prevalence of diabetes and prediabetes among people with lean or non-obese non-alcoholic fatty liver disease (NAFLD).
Effect of fasting-mimicking diet on markers of autophagy and metabolic health in human subjects.
This pilot randomized clinical trial assessed whether an 8-day fasting-mimicking diet (FMD) affected autophagic flux and metabolic markers in 30 healthy participants randomized to ProLon, FMD2, or control.
November 20253
Orforglipron, an oral small-molecule GLP-1 receptor agonist, for the treatment of obesity in people with type 2 diabetes (ATTAIN-2): a phase 3, double-blind, randomised, multicentre, placebo-controlled trial.
ATTAIN-2 was a 72-week, phase 3, double-blind, randomised, multicentre, placebo-controlled trial of once-daily oral orforglipron added to lifestyle modification in adults with type 2 diabetes and BMI of at least 27…
Diabetes Self-Care among South Asians in Western Countries: A Systematic Review.
This mixed-methods systematic review synthesised qualitative and quantitative evidence on diabetes self-care among South Asians living in Western countries.
Weight Loss, Obesity Medication, and Risk of Obesity-Associated Cancer: A Meta-Analysis of Randomized Controlled Trials.
This meta-analysis of randomized controlled trials assessed whether antiobesity medications (AOMs) and medication-mediated weight loss were associated with obesity-associated cancer risk in people with overweight or…
October 20252
The influence of intermittent fasting on body metrics, lipid profile, and physical performance in young and middle-aged men.
This randomized controlled trial assessed five months of intermittent fasting, four days per week, in 40 active men aged 23–28 or 46–59 years.
Oral semaglutide for weight loss and liver fibrosis in overweight and obesity: A randomized controlled trial.
This randomized, open-label, controlled trial compared oral semaglutide plus diet and activity counselling with counselling alone in adults with overweight or obesity without diabetes.
September 20253
Growth hormone deficiency after moderate traumatic brain injury with normal (or high) IGF-1; a case report demonstrating benefit of replacement therapy and clinical pearls for diagnosis.
A patient developed persistent symptoms after moderate traumatic brain injury and was ultimately diagnosed with growth hormone deficiency.
Impact of empagliflozin and dapagliflozin on sudden cardiac death: A systematic review and meta-analysis of adjudicated randomized evidence.
This systematic review and meta-analysis assessed sudden cardiac death (SCD) with empagliflozin or dapagliflozin in people with type 2 diabetes, heart failure, or chronic kidney disease.
X-linked Osteoporosis due to PLS3 Pathogenic Variant: Case Report on Zoledronic Acid Treatment in Siblings.
Two brothers presented with recurrent peripheral fractures and vertebral compression fractures, alongside low bone mineral density.
August 20253
Menopause and weight loss (ME-WEL) randomised controlled trial: an e-health cognitive-behavioural group intervention for weight management in postmenopausal women.
The ME-WEL randomised controlled trial assessed an 8-week e-health cognitive-behavioural group intervention for weight management in postmenopausal women with overweight or obesity.
A Case of Carney Complex with Pontine Glioma.
An 11-year-old girl with a history of pontine glioma treated with chemotherapy and radiotherapy in early childhood presented with weight gain and short stature.
Hereditary Hypophosphatemic Rickets with Hypercalciuria-Importance of Further Evaluation when Clinical Suspicion is Strong.
The report describes two children with hereditary hypophosphatemic rickets with hypercalciuria (HHRH). A 5.5-year-old presented with rickets, an abnormal bone profile and normal vitamin D; urinary phosphate studies…
July 20251
May 20253
A Rare Presentation of HIST1H1E Syndrome with Short Stature and Multiple Pituitary Hormone Deficiencies.
A 17-year-old male was evaluated for short stature and had characteristic facial features and neurodevelopmental delay. Genetic testing identified a heterozygous pathogenic H1-4 variant on chromosome 6p22.2, confirming…
Noninferiority of Copper Dressings Than Negative Pressure Wound Therapy in Healing Diabetic Wounds: A Randomized Clinical Trial.
This randomized clinical trial compared copper oxide–impregnated dressings (COD) with negative pressure wound therapy (NPWT) in patients with type 1 or type 2 diabetes and noninfected wounds eligible for NPWT.
Accuracy of Factory-Calibrated Continuous Glucose Monitors in Critically Ill Patients Receiving Intravenous Insulin: A Prospective Clinical Trial of Two Leading Systems.
This nonrandomized, open-label, clinically blinded prospective trial assessed the accuracy of two factory-calibrated continuous glucose monitors in 40 critically ill hospitalized patients receiving continuous…
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