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1998 articles
October 202624
Manual compared to automated closed-loop oxygen control strategies in hospitalised adults: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed randomised controlled trials comparing closed-loop oxygen control (CLOC) with manual adjustment in hospitalised adults receiving noninvasive oxygen.
Silent danger behind the forehead: Pott's puffy tumour presenting without systemic symptoms.
A man in his 50s developed progressive, painless forehead swelling despite multiple courses of antibiotics, without systemic symptoms.
Effects of remimazolam versus propofol on cerebral oxygenation in elderly patients undergoing prone spine surgery: study protocol for a randomised controlled trial.
This article describes the protocol for a prospective, single-centre randomised controlled trial comparing remimazolam with propofol-based total intravenous anaesthesia in elderly patients undergoing elective thoracic…
Dose- and modality-specific effects of exercise on BDNF and depression in middle-aged and older adults with mild cognitive impairment: A Bayesian network meta-analysis.
This Bayesian network dose-response meta-analysis examined randomized controlled trials of exercise in adults aged 50 years or older with mild cognitive impairment (MCI), assessing peripheral brain-derived neurotrophic…
Systematic Review and Meta-Analyses of Time-Use, Productivity, and Labor Outcomes Among Unpaid Cancer Caregivers.
This systematic review and meta-analysis pooled evidence on time use and labor outcomes among unpaid caregivers of adults with cancer.
The efficacy of surgical interventions for trigeminal neuralgia in multiple sclerosis: A systematic review.
This systematic review with narrative synthesis assessed surgical treatments for trigeminal neuralgia in people with multiple sclerosis, using studies reporting Barrow Neurological Institute Pain Scale outcomes.
Early interventions for primary care patients with stress-related mental ill health: a randomised controlled non-inferiority trial of a nurse-led collaborative care intervention versus cognitive behavioural therapy.
This randomised controlled non-inferiority trial compared nurse-led collaborative care (CC) with psychologist-guided self-help cognitive behavioural therapy (GSH-CBT) in 172 adults with mild to moderate stress-related…
Costs and health-related quality of life of non-operative and surgical treatment modalities for displaced distal radius fractures: a comprehensive overview based on the CAST study.
This cost and health-related quality-of-life analysis used data from the multicenter cluster-randomized CAST trial of adults with displaced distal radius fractures.
Betaine supplementation modulates mitochondrial and redox-related adaptations in premenopausal women with overweight: a randomized controlled trial.
This randomized controlled trial examined whether eight weeks of betaine supplementation (3 g/d) affected mitochondrial-associated and redox measures in premenopausal women with overweight or obesity.
A comparison of perioperative outcomes for da Vinci robotic-assisted, laparoscopic and open surgery in oncologic procedures: a systematic literature review and meta-analysis of evidence from China.
This systematic review and meta-analysis pooled 116 comparative studies published from 2010 to 2024 on da Vinci robot-assisted surgery (dV-RAS) versus laparoscopic/video-assisted thoracoscopic surgery (LAP/VATS) or open…
Surgeon task load, ergonomics, and clinical outcomes in laparoscopic versus robotic-assisted inguinal hernia repair: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis examined randomized controlled trials comparing robotic-assisted (RIHR) with conventional laparoscopic inguinal hernia repair (LIHR), focusing on surgeon workload, ergonomics…
A 45-Year-Old Woman With 30-Year History of a Nodule of the Earlobe Diagnosed as Lupus Vulgaris (Cutaneous Tuberculosis).
A 45-year-old woman had a painless, intermittently itchy lesion on her right earlobe for more than 30 years. It appeared as a red, thickened plaque with yellow papules and pustules.
Disparities in GLP-1RA and SGLT2i Uptake: a Systematic Review and an Equity-First Framework for Cardiovascular-Kidney-Metabolic Care.
This systematic review synthesised U.S. evidence on disparities in prescribing and initiation of GLP-1 receptor agonists and SGLT2 inhibitors, and proposed an equity-first framework for cardiovascular-kidney-metabolic…
HIV care cascade of adolescents and young adults in sub-Saharan Africa: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed progress toward the UNAIDS 95-95-95 targets among adolescents and young adults living with HIV in sub-Saharan Africa. It included 37 studies from 13 countries.
In vitro correction of venom-induced coagulopathy in Daboia russelii envenomation demonstrated using tranexamic acid-modified rotational thromboelastometry.
A man in his late 40s presented soon after Russell’s viper envenomation with local signs and a prolonged modified Lee and White clotting time, despite normal prothrombin and activated partial thromboplastin times.
Scleral perforation in a young adult with Burkitt lymphoma.
A man in his 20s with Burkitt lymphoma receiving chemotherapy was referred for lagophthalmos and left facial nerve palsy. Weeks later, he developed acute scleral perforation.
Meckel's diverticulum leading to axial torsion and volvulus of the small bowel.
A patient presented with small-bowel obstruction caused by a giant Meckel’s diverticulum measuring 22 cm × 11 cm × 9.8 cm. The diverticulum produced mass effect and was associated with axial torsion and volvulus of the…
Co-supplementation of zinc and probiotic on oxidative stress markers and sleep quality index in irritable bowel syndrome patients: a double-blind randomized controlled trial.
This parallel, double-blind randomised controlled trial assessed zinc alone and zinc plus probiotics in 84 people with irritable bowel syndrome over 90 days, comparing both with placebo.
Emerging risks of health optimisation: refractory nausea associated with peptide injections reported to contain retatrutide.
A woman in her mid-20s presented with five days of persistent nausea, repeated vomiting, loose stools and markedly reduced oral intake.
Fatal haemophagocytic lymphohistiocytosis and atypical haemolytic uraemic syndrome following coronavirus disease 2019 infection.
A previously healthy woman in her early 30s developed rash, fever and arthralgia three weeks after SARS-CoV-2 infection, followed by rapidly progressive multiorgan failure.
Staged bilateral MR-guided focused ultrasound thalamotomy in a patient with cerebral cavernous malformations.
A man in his late 60s with medication-refractory essential tremor was found on preoperative MRI to have cavernous malformations in the left caudate head and basal ganglia, with an associated developmental venous anomaly…
Facial nerve palsy and hypertension; unusual presentation of apparent mineralocorticoid excess (AME) syndrome in a paediatric patient.
A boy in early childhood presented after two days of right-sided facial palsy and was found to have severe hypertension with end-organ damage.
Atypical presentations of Lhermitte's sign after treatment for human papillomavirus-associated oropharyngeal squamous cell carcinoma.
Two patients with human papillomavirus-associated oropharyngeal squamous cell carcinoma developed Lhermitte’s sign after chemoradiotherapy.
Idiopathic multicentric Castleman disease in an HIV-positive child.
A preadolescent girl with HIV presented with fever and unilateral facial and neck swelling. Examination showed generalised lymphadenopathy, hepatosplenomegaly, hypertension and haematuria, initially suggesting…
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