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1018 articles

March 20267

Case ReportInfectious DiseasesOpen access

An 8-month-old infant with hepatic tularemia: a case report.

An 8-month-old infant developed fever up to 40 °C, vomiting, and diarrhea after a nuchal tick bite with local wound infection. Fever persisted despite anti-inflammatory medication and antibiotics.

Wien Med WochenschrMar 5, 2026Read case
Case ReportPediatrics

Complete congenital agenesis of major salivary glands: case report and systematic review of the literature.

This report concerns congenital absence of all major salivary glands, a developmental cause of xerostomia in children. The accompanying systematic review identified 20 reported cases in patients younger than 18 years…

J Stomatol Oral Maxillofac SurgMar 4, 2026Read case
Case ReportOrthopedic Surgery

Midshaft ulnar stress reaction in the adolescent female athlete: a case series.

Three adolescent female softball pitchers developed midshaft ulnar stress reactions associated with repetitive, high-stress upper-extremity activity. Advanced imaging established the diagnoses.

Res Sports MedMar 4, 2026Read case
Clinical ResearchPediatrics

Universal Psychosocial Screening in Hospitalized Pediatric Patients: A Randomized Control Trial.

This randomized controlled trial evaluated universal psychosocial screening with MyHEARTSMAP among 289 children admitted through an emergency department.

Clin Child Psychol PsychiatryMar 4, 2026Read summary
Clinical ResearchOrthopedic Surgery

Surgical Versus Nonsurgical Management of Pediatric Medial Epicondyle Fractures: An Updated Systematic Review.

This Level III systematic review compared operative and nonoperative management of isolated medial epicondyle fractures in children.

J Pediatr OrthopMar 2, 2026Read summary
Case ReportMedical GeneticsOpen access

Optimizing diagnosis and management of patients with ENPP1 deficiency: an expert opinion.

This expert-opinion article discusses ENPP1 deficiency, a genetic disorder caused by loss-of-function mutations and associated with low circulating inorganic pyrophosphate, bone hypomineralization, soft-tissue…

J Endocrinol InvestMar 2, 2026Read case
Clinical ResearchObstetrics & GynecologyOpen access

Randomized, placebo-controlled phase 3 trial evaluating safety, immunogenicity, and reactogenicity of RSVPreF3-Mat in high-risk pregnant women and their infants.

This phase 3 randomized, placebo-controlled trial assessed RSVPreF3-Mat safety, reactogenicity, and immunogenicity in high-risk pregnant women and their infants.

Hum Vaccin ImmunotherMar 1, 2026Read summary

February 202617

Clinical ResearchPediatrics

Early establishment of Bifidobacterium-dominant microbiome in planned cesarean-born infants via Bifidobacterium breve strain Yakult supplementation: A randomized, double-blind, placebo-controlled, parallel-group pilot study.

This single-center, randomized, double-blind, placebo-controlled pilot study assessed Bifidobacterium breve strain Yakult (BbrY) given during the first month of life to healthy, full-term Japanese infants born by…

Pediatr NeonatolFeb 28, 2026Read summary
Clinical ResearchPediatrics

Kidney and Blood Pressure Outcomes in Children Surviving at Least 6 Months after Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis assessed late kidney and high blood pressure outcomes in children surviving at least 6 months after hematopoietic stem cell transplantation (HSCT).

Transplant Cell TherFeb 28, 2026Read summary
Clinical ResearchNephrologyOpen access

Single-dose versus multi-dose steroid therapy in pediatric nephrotic syndrome: a systematic review and meta-analysis.

This systematic review and meta-analysis compared once-daily with divided-dose prednisolone in children with steroid-sensitive nephrotic syndrome.

Pediatr NephrolFeb 28, 2026Read summary
Clinical ResearchCardiology

Early Versus Late Extubation in Pediatric Cardiac Surgery: A Systematic Review.

This PRISMA-guided systematic review compared early or immediate extubation with traditional delayed extubation after congenital heart surgery in children.

World J Pediatr Congenit Heart SurgFeb 27, 2026Read summary
Clinical ResearchPediatrics

The effect of prebiotic intervention foods on caregiver-reported infant sleep and caregiver sleep quality during complementary feeding- secondary analysis of a randomized control trial.

This secondary outcome analysis of a three-arm parallel randomized controlled trial examined caregiver-reported infant sleep and caregiver sleep quality during the first four months of complementary feeding.

Nutr NeurosciFeb 27, 2026Read summary
Clinical ResearchPlastic Surgery

Orofacial Cleft Disparities in American Indian and Alaska Native Populations: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined orofacial cleft prevalence, care access, and outcomes among American Indian and Alaska Native (AI/AN) populations in US-based studies.

Cleft Palate Craniofac JFeb 25, 2026Read summary
Clinical ResearchPlastic Surgery

Disparities in Cleft Care for Hispanic/Latino Patients in the United States: A Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis examined US studies comparing cleft care for Hispanic/Latino children with care for non-Hispanic White children.

Cleft Palate Craniofac JFeb 25, 2026Read summary
Case ReportMedical Genetics

A Novel Association Between Mandibulofacial Dysostosis with Microcephaly and Congenital Diaphragmatic Hernia.

A late-preterm female had multiple congenital malformations identified prenatally, including congenital diaphragmatic hernia (CDH).

Cleft Palate Craniofac JFeb 25, 2026Read case
Clinical ResearchPediatrics

Effects of time-restricted eating on blood pressure in children: A cluster randomized controlled trial.

This 12-month, three-arm cluster-randomized controlled trial in two schools evaluated time-restricted eating (TRE) among 192 children and adolescents with elevated blood pressure.

Clin Exp HypertensFeb 24, 2026Read summary
Clinical ResearchInfectious Diseases

Body Composition Changes in Children Living With HIV Initiated on Dolutegravir or Protease Inhibitors in the CHAPAS-4 Trial.

This randomized factorial trial analysis examined body-composition changes over 96 weeks in children with HIV switching to second-line antiretroviral therapy.

Pediatr Infect Dis JFeb 24, 2026Read summary
Case ReportMedical Genetics

Immune Dysregulation, Polyendocrinopathy and Enteropathy X-Linked Syndrome with Neonatal Onset: A Case Report.

A male infant born preterm at 30 weeks’ gestation developed enteropathy, eczema, eosinophilia, transfusion-dependent cytopenias, recurrent infections, and a desquamative rash.

Acta Med PortFeb 23, 2026Read case
Clinical ResearchPediatricsOpen access

Acceptability and Feasibility of an Educational Intervention to Improve Researcher-Participant Interactions in a Neonatal Intensive Care Unit Clinical Trial: Research Team Feedback on the BRIEF Intervention.

This single-site pilot study evaluated the feasibility and acceptability of Better Research Interactions for Every Family (BRIEF), a multipart educational intervention for improving research-team conversations with…

Am J PerinatolFeb 20, 2026Read summary
Clinical ResearchNephrologyOpen access

Steroid-induced adrenal insufficiency in children with nephrotic syndrome: a systematic review.

This systematic review evaluated steroid-induced adrenal insufficiency (AI) in children with idiopathic nephrotic syndrome treated with corticosteroids.

Pediatr NephrolFeb 18, 2026Read summary
Case ReportEndocrinology

Severe congenital toxoplasmosis with isolated central hypothyroidism: A rare case report.

A preterm newborn at 35 weeks’ gestation had severe congenital toxoplasmosis, confirmed by positive IgM/IgG serology and cerebrospinal fluid PCR.

J Neonatal Perinatal MedFeb 18, 2026Read case
Clinical ResearchCardiologyOpen access

Tricuspid Regurgitation and Impact of Surgical Valve Intervention in the Single Ventricle Reconstruction Trial.

This analysis of the Pediatric Heart Network’s Single Ventricle Reconstruction trial examined serial tricuspid regurgitation (TR) and transplant-free survival in children with single right ventricle anomalies followed…

Pediatr CardiolFeb 18, 2026Read summary
Case ReportMedical Genetics

A case of Kabuki syndrome with congenital pulmonary airway malformation.

A child with delayed physical growth and neurological, psychological, and intellectual development had facial features including arched eyebrows and elongated eyelids slanting downward.

J Investig MedFeb 17, 2026Read case
Clinical ResearchAnesthesiology

Performance of published scoring tools for predicting the risk of perioperative respiratory adverse events in children - An evaluation in a large paediatric cohort.

This post-hoc secondary analysis evaluated six published risk scores for predicting perioperative respiratory adverse events (PRAE) in 12,364 cases of paediatric general anaesthesia.

Anaesth Crit Care Pain MedFeb 17, 2026Read summary

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