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497 articles
October 202624
A Giant Intra-Abdominal Plasmablastic Neoplasm Favoring Lymphoma Mimicking an Exacerbation of Severe Fistulizing Crohn's Disease: A Case Report.
A 44-year-old woman with severe fistulizing Crohn’s disease developed progressive systemic deterioration despite partial intestinal stabilization.
Pediatric anti-GBM crescentic glomerulonephritis: partial renal recovery following plasmapheresis and mycophenolate mofetil.
A 14-year-old girl presented with acute edema and hypertension. Investigations showed hematuria, proteinuria, hypoalbuminemia, worsening renal function, and positive anti-GBM antibodies.
Histiocytoid melanoma presenting as lymphadenopathy and mimicking Rosai-Dorfman disease.
A patient presented with large, unilateral inguinal lymphadenopathy. Excisional biopsy showed expanded lymph-node sinuses containing large cells with abundant granular eosinophilic cytoplasm, eccentric nuclei, and…
Astrocytic and Axonal Injury Biomarkers in AQP4 Antibody-Positive NMOSD: Insights From PREVENT and CHAMPION-NMOSD.
This biomarker analysis used samples from the phase 3 PREVENT and CHAMPION-NMOSD trials to assess serum GFAP and NfL in people with AQP4 antibody-positive NMOSD receiving eculizumab or ravulizumab.
Immunohistochemistry for c-MET, HLA class II, and CD68 does not show prognostic value in early-stage classic Hodgkin lymphoma patients in the EORTC-GELA H9 intergroup randomised trial.
This case-cohort biomarker validation study examined whether immunohistochemical expression of c-MET, HLA class II, or CD68 predicted progression-free survival in patients with early-stage classic Hodgkin lymphoma…
Phaeohyphomycosis in a Solid Organ Transplant Recipient: Case Report of a New Pathogenic Species of Kirschsteiniothelia.
A 63-year-old immunocompromised recipient of a combined heart-lung transplant developed a subcutaneous thigh lesion. Surgical debridement and histopathology indicated a deep fungal infection.
Histologically Confirmed Brain Metastasis Arising From Giant Cell Tumor of Bone: an Uncommon Entity and a Challenging Condition.
A 39-year-old patient with no significant medical history had a giant cell tumor of bone (GCTB) in the left distal femur, treated with preoperative denosumab and resection with prosthetic reconstruction.
Pancreatic Tuberculosis Mimicking Pancreatic Cancer in a Young Immunocompetent Man: A Case Report and Literature Review.
A 34-year-old HIV-seronegative Afghan man had a year of intermittent epigastric pain, nausea, and vomiting. CT showed a 57×30 mm multiloculated hypoattenuating mass in the pancreatic head without biliary dilation; serum…
Successful treatment of hairy cell leukemia with TP53 abnormality using cladribine combined with low-dose rituximab: a case report and literature review.
An elderly man with classical hairy cell leukemia (HCL) had BRAF V600E positivity, a TP53 deletion detected by fluorescence in situ hybridization, and bone marrow fibrosis.
Artificial intelligence-powered renal pathology for glomerular disease classification: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the performance of artificial intelligence (AI) models in classifying glomerular diseases using pathology images.
Immune-related colitis following head and neck reconstructive surgery in a patient receiving long-term nivolumab.
A man with gastric cancer, receiving long-term nivolumab and prednisolone for immune-related myositis, underwent subtotal glossectomy for advanced tongue cancer. On postoperative day 4, he developed grade 3 diarrhoea.
Adamantinoma-like Ewing sarcoma of the bladder.
A patient presented with a bladder tumor initially diagnosed as urothelial carcinoma following transurethral resection. After receiving neoadjuvant chemotherapy with methotrexate, vinblastine, doxorubicin, and…
Eosinophilic angiocentric fibrosis in paediatric IgG4-related disease.
A young girl presented with a 1.5-year history of progressive bilateral upper eyelid swelling and proptosis, more pronounced on the right.
Haemophagocytic lymphohistiocytosis triggered by Kikuchi-Fujimoto disease: a diagnostic challenge.
A man in his 40s presented with fever, confusion, a widespread erythematous rash, weight loss, and generalized lymphadenopathy over three weeks.
Same-day diagnosis and robotic resection of rare primary pulmonary melanoma: a robotic bronchoscopy-guided approach.
A man in his 70s presented with a lingular pulmonary nodule suspicious for non-small cell lung cancer. He underwent robotic navigation bronchoscopy for biopsy, which was followed by robotic-assisted thoracic surgery.
Early-onset VEXAS syndrome mimicking orbital cellulitis and successfully treated with allogeneic hematopoietic stem cell transplantation.
A 25-year-old male presented with recurrent fever, weight loss, arthralgia, and symptoms resembling orbital cellulitis. Imaging revealed orbital soft tissue inflammation, while laboratory tests showed macrocytic anemia…
Rupture of Left Ventricular Aneurysm in Infant: Case Report.
A preterm infant hospitalized from birth with necrotizing enterocolitis, later complicated by ascending-colon narrowing requiring surgery, had persistent infections with Staphylococcus haemolyticus and then…
Adrenal metastasis from papillary thyroid cancer: staged surgical resection.
A man in his 70s with a history of papillary thyroid carcinoma presented with recurrence in the right cervical lymph nodes and a right adrenal mass measuring 5.7×6.5 cm. A CT-guided biopsy confirmed metastatic disease.
Gastrointestinal manifestations of IgA vasculitis guiding treatment in an adult patient.
A man in his 20s presented with abdominal pain, post-prandial vomiting, a purpuric rash, arthralgia, and hypertension. Urine studies indicated subnephrotic range proteinuria, and colonoscopy revealed ileal ulceration.
Reduced venesection requirement as a clue to occult colorectal cancer in hereditary haemochromatosis.
A man in his late 70s with hereditary haemochromatosis experienced an unexpected cessation of his usual venesection for iron management, despite no gastrointestinal symptoms or anemia.
Cutaneous leukocytoclastic vasculitis with concurrent colitis of uncertain aetiology.
A female in her 20s presented with biopsy-confirmed cutaneous leukocytoclastic vasculitis and significant gastrointestinal symptoms, including recurrent rectal bleeding and abdominal pain.
Peritoneal loose body: an incidental finding, a challenging diagnosis and multimodal assessment to avoid resections.
A man in his early 40s presented with urinary symptoms and was found to have a right ureteric calculus, hydronephrosis, and a urinary tract infection.
Fatal drug-induced liver injury in the setting of abemaciclib therapy for metastatic breast cancer.
A Hispanic woman in her mid-60s with metastatic ER+/HER2- breast cancer developed severe mixed hepatocellular-cholestatic injury one month after starting abemaciclib with letrozole.
Multisystem imaging findings as diagnostic red herrings in Wilson's disease.
A previously healthy man in his 20s presented with fever, cough, jaundice, and a right-sided pleural effusion. Initial tests revealed significant hepatic dysfunction, and imaging showed cirrhotic liver morphology…
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