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1998 articles
October 202624
Determining the minimal important difference of EQ-5D-5 L utility values in CIDP patients using data from a large clinical trial.
This analysis of data from the ADHERE randomized controlled trial estimated the minimal important difference (MID) in EQ-5D-5 L utility values for patients with chronic inflammatory demyelinating polyradiculoneuropathy…
Clinical performance of resin infiltration and different sealant modalities in noncavitated pits and fissures: a split-mouth randomized controlled trial.
This split-mouth randomized controlled trial compared resin infiltration, two sealant approaches, and their combination for noncavitated occlusal lesions in 128 permanent molars from 32 children aged 7–14 years.
Clinical and radiographic success of bioflex versus stainless steel crowns using the hall technique in primary molars: a 12-month randomized controlled trial.
This two-arm randomized controlled trial compared BioFlex crowns (BFCs) with stainless-steel crowns (SSCs), both placed using the Hall Technique, in healthy children aged 4–6 years with carious mandibular second primary…
Minimally invasive management of pulmonary artery bleed in robotic left upper lobectomy.
A patient undergoing robotic left upper lobectomy for a Pancoast tumour developed an intraoperative pulmonary artery bleed.
Molecular-genetic mechanisms of cerebral arteriovenous malformations: A systematic review of germline, somatic and experimental evidence.
This systematic review synthesised human genetic, molecular, and experimental evidence on cerebral arteriovenous malformation (AVM) formation, clinical course, and potential therapeutic targets.
Drug-coated balloons in coronary disease: meta-analysis comparing sirolimus- and paclitaxel-coated technologies.
This systematic review and meta-analysis compared sirolimus-coated balloons (SCBs) with paclitaxel-coated balloons (PCBs) for coronary interventions.
Crescents in native kidney biopsies from patients with IgA nephropathy and the risk of recurrence after kidney transplantation: a retrospective cohort study, systematic literature review and meta-analysis of observational studies.
This retrospective cohort study, systematic review and meta-analysis examined whether glomerular crescents in native kidney biopsies predict IgA nephropathy (IgAN) recurrence after kidney transplantation.
Firstline treatment with ruxolitinib versus best available therapy in patients with polycythemia vera: results from the randomized RuxoBEAT trial.
The multicenter randomized RuxoBEAT trial compared first-line ruxolitinib (RUX) with best available therapy (BAT) in patients with polycythemia vera.
Effects of exposure to negative and positive social media content about vaping and nicotine addiction on beliefs and intentions to use e-cigarettes among young adults in the United States: results from a randomized controlled experiment.
This randomized controlled experiment assigned 1,816 young adults in the United States to view real, publicly accessible social media videos presenting nicotine addiction positively, negatively, or in unrelated control…
Silver diamine fluoride versus conventional restorative treatment for dental caries in primary teeth of children: a meta-analysis.
This meta-analysis compared 30% to 38% silver diamine fluoride (SDF) with conventional restorative approaches for caries control in children with carious primary teeth.
Anbalcabtagene autoleucel (PD-1 and TIGIT knockdown CD19 CAR T-cell therapy) for relapsed or refractory LBCL: the CRC01-01 trial.
The multicenter phase 1/2 CRC01-01 trial evaluated anbalcabtagene autoleucel, a CD19 CAR T-cell therapy with PD-1 and TIGIT knockdown, in patients with relapsed or refractory large B-cell lymphoma.
Tuberculosis-Associated Longitudinally Extensive Transverse Myelitis.
A 51-year-old man with a year of chronic non-productive cough and about 20 days of fever and headache presented with encephalopathy but no focal neurological deficits.
From metastatic disease to no evidence of disease after conversion liver surgery in advanced gastric cancer with liver metastases: A case report.
A 54-year-old woman with initially unresectable, HER2-negative, pMMR-by-IHC, EBER-positive gastric cancer and synchronous liver metastases received tislelizumab-based chemotherapy, with regimen changes after suspected…
Thulium laser-assisted delivery of growth factors for treating androgenetic alopecia - a randomized, controlled, clinical study.
This pilot randomized controlled study evaluated non-ablative fractional laser (NAFL)-assisted delivery of a biomimetic growth factor serum, with or without red light therapy, in patients with androgenetic alopecia.
Unexpected finding of AA amyloidosis with novel genetic variants in the MEFV gene in patients undergoing kidney biopsy for proteinuria. A case series.
The report describes patients undergoing kidney biopsy for proteinuria in whom AA amyloidosis was identified, alongside MEFV gene variants.
A self-controlled case series to evaluate the effects of clinical trial eligibility criteria on biologic-associated reductions in severe asthma exacerbations: an analysis of the CHRONICLE study.
This study examined whether eligibility criteria used in biologic trials identify adults with severe asthma who are more likely to benefit.
Patterns and predictive factors of hearing loss following microvascular decompression for hemifacial spasm: a systematic review.
This systematic review and meta-analysis assessed the prevalence, patterns, and potential risk factors for hearing loss after microvascular decompression for hemifacial spasm.
Clinical Outcomes and Complications of Extracorporeal Membrane Oxygenation (ECMO) in Adult Patients With COVID-19 in Central and Eastern Europe: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled observational studies of adults with COVID-19 treated with ECMO in Central and Eastern Europe. Twelve studies covered 802 patients from six countries.
Safety and immunogenicity of the 24-valent pneumococcal conjugate vaccine in healthy Chinese adults: two single-center, randomized, double-blind Phase 1 and Phase 2 trials.
Two single-center, randomized, double-blind Phase 1 and Phase 2 trials assessed the safety and immunogenicity of a 24-valent pneumococcal conjugate vaccine (PCV24) in healthy Chinese adults aged 18 years or older.
Hyponatremic-Hypertensive Syndrome as a Rare Manifestation of Renovascular Hypertension: A Case Series.
Two girls, aged 4 and 9 years, presented with severe hypertension and electrolyte disturbances, including hyponatremia and hypokalemia, with elevated renin-aldosterone activity.
Agreement Between In-Person and Telephone Application of the Informant Questionnaire on Cognitive Decline in the Elderly.
This methodological study assessed agreement between in-person and telephone administration of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), completed by caregivers or family members of older…
Clinical safety, tolerability, and efficacy of fospropofol disodium for sedation: a systematic review.
This systematic review and meta-analysis assessed randomized trials of fospropofol for procedural and ICU sedation. It included 10 studies: six procedural-sedation trials and four ICU-sedation trials.
Evaluating Improvement in Pain and Sensory Function When Using High-Frequency (10-kHz) Spinal Cord Stimulation in Individuals With Painful Diabetic Neuropathy: A Multicenter Randomized Controlled Trial (PDN-Sensory).
The multicenter randomized controlled PDN-Sensory trial evaluated 10-kHz spinal cord stimulation (SCS) plus conventional medical management (CMM) versus CMM alone in people with painful diabetic neuropathy.
Parent-child discrepancies in health-related quality of life in pediatric celiac disease: a systematic review and meta-analysis.
This systematic review and meta-analysis examined child–parent differences in health-related quality of life (HRQoL) among children and adolescents with celiac disease, using the disease-specific CDDUX questionnaire.
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