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1316 articles

October 202624

Clinical ResearchEndocrinology

Evaluating Improvement in Pain and Sensory Function When Using High-Frequency (10-kHz) Spinal Cord Stimulation in Individuals With Painful Diabetic Neuropathy: A Multicenter Randomized Controlled Trial (PDN-Sensory).

The multicenter randomized controlled PDN-Sensory trial evaluated 10-kHz spinal cord stimulation (SCS) plus conventional medical management (CMM) versus CMM alone in people with painful diabetic neuropathy.

Diabetes CareOct 21, 2026Read summary
Clinical ResearchUrology

Extended Ceftriaxone Prophylaxis and Postoperative Inflammation and Infection-Related Symptoms After Ureteral Lithotripsy with Negative Urine Cultures.

This single-center exploratory study, reported as randomized, compared extended preoperative ceftriaxone with a single prophylactic dose in 252 patients with negative urine cultures undergoing rigid ureteroscopic…

J Vis ExpOct 21, 2026Read summary
Clinical ResearchOphthalmology

EFFICACY AND SAFETY OF SUBTHRESHOLD LASER IN PATIENTS WITH ACUTE CENTRAL SEROUS CHORIORETINOPATHY: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis assessed the efficacy and safety of subthreshold laser for acute central serous chorioretinopathy (CSC), including six randomized controlled trials with 401 participants.

RetinaOct 21, 2026Read summary
Clinical ResearchOrthopedic Surgery

A Systematic Review of Complications Following Elective Foot and Ankle Surgery.

This systematic review synthesized complication profiles and risk factors in adults undergoing elective foot and ankle surgery.

J Foot Ankle ResOct 20, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Effectiveness and safety of adjunct interventions for external cephalic version in breech presentation: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed adjunct and procedural strategies for external cephalic version (ECV) in pregnant women with breech presentation, drawing on 10 randomised controlled trials with 2,745…

Rev Bras Ginecol ObstetOct 20, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Comparative perioperative and oncological outcomes of the da Vinci Xi versus Si robotic surgical systems in rectal cancer surgery: a systematic review and meta-analysis.

This systematic review and meta-analysis compared perioperative and oncological outcomes with da Vinci Xi versus Si systems in rectal cancer surgery.

J Robot SurgOct 20, 2026Read summary
Clinical ResearchPsychiatryOpen access

Effectiveness and Influencing Factors of Drama-Based Interventions for Social Skills in Children and Adolescents with Autism Spectrum Disorder: A Meta-Analysis.

This meta-analysis assessed drama-based interventions for social skills in children and adolescents with autism spectrum disorder (ASD), drawing on 16 controlled studies involving 703 participants.

Res Child Adolesc PsychopatholOct 20, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Robotic-assisted living-donor hysterectomy for uterus transplantation: a systematic review of surgical techniques, donor safety, and recipient outcomes.

This systematic review assessed robotic-assisted hysterectomy in living donors for uterus transplantation, examining surgical methods, donor safety, graft outcomes, and reproductive success.

J Robot SurgOct 20, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Entinostat plus exemestane for hormone receptor-positive advanced breast cancer: long-term overall survival results from the EOC103A3101 randomized controlled trial.

This randomized controlled trial assessed long-term overall survival with entinostat plus exemestane versus placebo plus exemestane in 354 patients with hormone receptor-positive, HER2-negative advanced breast cancer…

Signal Transduct Target TherOct 20, 2026Read summary
Clinical ResearchPediatrics

The impact of recreational beach tennis associated with nutritional counseling on cardiometabolic risk factors in adolescents: a randomized clinical trial.

This 12-week randomized clinical trial compared recreational beach tennis alone with beach tennis plus nutritional counseling in 40 adolescents aged 11–14 years.

Arch Endocrinol MetabOct 20, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Neurosurgical manifestations and management of mucopolysaccharidoses: A systematic review.

This PRISMA-guided systematic review synthesized contemporary reports of neurosurgical manifestations and management across mucopolysaccharidosis (MPS) subtypes.

Neurosurg RevOct 20, 2026Read summary
Clinical ResearchPediatricsOpen access

Oxygen vs Air at Birth for Moderate- to Late-Preterm Infants: The AIROPLANE Cluster Randomized Crossover Trial.

The AIROPLANE trial was an unblinded, cluster randomized crossover study at 26 Australian maternity hospitals comparing initial oxygen concentrations of 0.30 and 0.21 during the first 3 minutes of respiratory support…

JAMAOct 20, 2026Read summary
Clinical ResearchPediatricsOpen access

Levetiracetam versus valproate for new-onset or previously treated but inadequately controlled epilepsy in children: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis compared levetiracetam with valproate in children aged 0–18 years with new-onset or inadequately controlled epilepsy.

Eur J Clin PharmacolOct 20, 2026Read summary
Clinical ResearchPediatricsOpen access

Ciliated hepatic foregut cyst in children and adolescents: a systematic review of clinical presentation, diagnosis, management, and outcomes.

This PRISMA 2020 systematic review descriptively synthesised case reports and case series of histopathologically confirmed ciliated hepatic foregut cysts in patients aged 19 years or younger.

Pediatr Surg IntOct 20, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Combination of oral fluoropyrimidines and EGFR-directed antibodies in frail patients with metastatic colorectal cancer: a systematic review.

This systematic review assessed phase II and III evidence for oral fluoropyrimidines combined with EGFR-directed antibodies in patients with RAS wild-type metastatic colorectal cancer, including those considered unfit…

J Cancer Res Clin OncolOct 20, 2026Read summary
Clinical ResearchRheumatologyOpen access

The Effect of Mindfulness-Based Cognitive Therapy on Kinesiophobia in Older Adults with Chronic Knee Osteoarthritis: A Randomized Controlled Trial.

This randomized controlled trial evaluated mindfulness-based cognitive therapy (MBCT) for kinesiophobia in 56 older adults with chronic knee osteoarthritis in Kashan, Iran.

Clin Interv AgingOct 20, 2026Read summary
Clinical ResearchOncology (Medical)

Meta-analysis of 990 EBV genomes identifies EBER2 SNP7048 and its interaction with HLA-A*11:01 driving nasopharyngeal carcinoma risk.

This meta-analysis examined whether EBV genetic variation and host genetics are associated with nasopharyngeal carcinoma (NPC) across endemic populations in Singapore, Hong Kong, and China’s Guangdong and Guangxi…

Proc Natl Acad Sci U S AOct 20, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Neoadjuvant Therapy for Gastric Adenocarcinoma with Signet Ring Cells: A Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis assessed neoadjuvant chemotherapy followed by surgery versus upfront gastrectomy in adults with signet ring cell-containing gastric cancer.

J Gastrointest CancerOct 20, 2026Read summary
Clinical ResearchNeurologyOpen access

The effect of seizure-free period on seizure recurrence following antiseizure medication withdrawal: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis examined whether the duration of seizure freedom before antiseizure medication (ASM) withdrawal is associated with subsequent seizure recurrence in people with…

J NeurolOct 20, 2026Read summary
Clinical ResearchPsychiatry

Complex post-traumatic stress disorder in refugees, asylum seekers, and internally displaced people: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis examined complex post-traumatic stress disorder (CPTSD) prevalence among refugees, asylum seekers, and internally displaced people.

Eur J PsychotraumatolOct 20, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Placebo effects of caffeine on sport performance: a systematic review and meta-analysis.

This systematic review and meta-analysis examined whether deceptively describing a placebo as caffeine affects sport performance in healthy adults.

J Int Soc Sports NutrOct 20, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Initial HIV Therapy for Adults and Treatment-Associated Weight Gain: The Opti-DOR Randomized Clinical Trial.

The Opti-DOR open-label, noninferiority randomized trial compared two initial antiretroviral regimens in 600 ART-naive adults at two South African sites; 99.5% of participants were Black African.

JAMAOct 20, 2026Read summary
Clinical ResearchGeriatricsOpen access

Optimizing exercise prescriptions for older adults with mild cognitive impairment: a dose-response network meta-analysis of modality-dose combinations on executive function.

This Bayesian dose-response network meta-analysis synthesized randomized controlled trials of repeated exercise programmes in adults aged 60 years or older with mild cognitive impairment.

PeerJOct 20, 2026Read summary
Clinical ResearchPulmonologyOpen access

Effects of resistance training on subjective sleep quality, excessive daytime sleepiness, and quality of life in patients with obstructive sleep apnea: a secondary analysis from a randomized controlled trial.

This secondary analysis of a randomized controlled trial examined eight weeks of resistance training in 25 adults with moderate to severe obstructive sleep apnea.

Sleep BreathOct 20, 2026Read summary

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