Trending archive
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1891 articles
January 202614
Finding the right time to initiate exercise rehabilitation following a cancer diagnosis: A systematic review and meta-analysis.
This systematic review and meta-analysis examined whether the timing of exercise rehabilitation affects outcomes for adults and children with cancer.
The efficacy and safety of CAR-T therapy in relapsed or refractory multiple myeloma patients: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed the efficacy and safety of CAR-T therapy in patients with relapsed or refractory multiple myeloma.
The gut microbiota-obesity axis in the pathogenesis and prognosis of breast cancer.
This systematic review examined evidence on how gut microbiota and obesity may interact in breast cancer (BC), drawing on literature published from July 2015 to January 2025.
Neoadjuvant chemotherapy plus cadonilimab followed by extra-fascial hysterectomy for International Federation of Gynecology and Obstetrics stage IB2 cervical cancer: a prospective, multi-center, single-arm, phase 2 trial.
This prospective, multicentre, single-arm phase II trial is evaluating whether neoadjuvant chemoimmunotherapy can enable less extensive surgery for treatment-naïve patients with FIGO 2018 stage IB2 cervical cancer.
Thiamine deficiency in oncology: Clinical insights from two cases of Wernicke's encephalopathy.
Two patients with cancer and significant malnutrition and weight loss developed neurological presentations consistent with Wernicke’s encephalopathy (WE).
A Functionally Constrained Immune Ecosystem in Microsatellite-stable Colorectal Cancer Resolved by Single-cell and Exome Profiling.
A 77-year-old woman underwent resection of a mismatch repair-proficient, microsatellite-stable colorectal cancer with low mutational burden and a synchronous adenoma.
Hereditary Diffuse Gastric Cancer With Poorly Differentiated Gallbladder Adenocarcinoma: A Case Report Suggesting Carcinogenesis in the Stomach and Gallbladder Caused by a Pathogenic Germline Variant in CDH1 .
A 67-year-old woman was referred for management of gallbladder cancer after cholecystectomy for progressive gallbladder wall thickening.
Successful Management of Ultra-high-risk Mixed Ovarian Germ Cell Tumor Using a Pediatric-inspired Intensive Chemotherapy Regimen: A Case Report.
A 33-year-old woman presented with acute hemoperitoneum and was found to have FIGO stage IVB mixed malignant ovarian germ cell tumor comprising 60% dysgerminoma, 40% choriocarcinoma, and focal yolk sac tumor.
Efficacy of S-1 Monotherapy for Salivary Duct Carcinoma With MYC Amplification.
A 70-year-old man with HER2-positive, androgen receptor-positive submandibular salivary duct carcinoma presented with multiple lung metastases.
Radiotherapy With Hyperthermia for Prostatic Ductal Adenocarcinoma: Primary and Salvage Cases.
Three patients with prostatic ductal adenocarcinoma received radiotherapy combined with regional hyperthermia: two with locally advanced cT3aN0M0 disease received definitive intensity-modulated radiotherapy, and one…
Dexamethasone Versus Dexmedetomidine as Adjuncts to Serratus Anterior Plane Block for Postoperative Analgesia After Modified Radical Mastectomy: A Randomized Clinical Trial.
This randomized clinical trial compared dexamethasone with dexmedetomidine as an adjunct to serratus anterior plane block in 126 female patients undergoing modified radical mastectomy.
Extraperitoneal Single-Port Robot-Assisted Bilateral Retroperitoneal Lymph Node Dis-section for Primary Non-Seminomatous Germ Cell Tumor: Technique and Surgical Considerations.
Retroperitoneal lymph node dissection (RPLND) is an established treatment option for clinical stage I-II non-seminomatous germ cell tumors (NSGCT), among which bilateral template dissection represents the most…
From Dysbiosis to Malignancy: The Female Genital Tract Microbiome in Endometrial Cancer; Insights from a Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined genital tract microbiome patterns across benign, premalignant, and malignant endometrial conditions.
Secondary Ophthalmic Artery Chemotherapy for Bilateral Retinoblastoma After Incomplete Response to Intravenous Chemotherapy: Initial Prospective Experience from a Resource-Limited Setting.
This prospective single-centre study assessed short-term outcomes of secondary ophthalmic artery chemotherapy (OAC) in 20 children with bilateral retinoblastoma whose eyes had responded incompletely to intravenous…
December 202510
Robotic-assisted versus standard laparoscopic surgery for colorectal cancer in obese patients: a systematic review and meta-analysis.
This systematic review and meta-analysis compared robotic-assisted with standard laparoscopic surgery for colorectal cancer in obese patients. Six studies involving 4215 patients were included.
The molecular mechanism of cuproptosis and research progress in pancreatic diseases.
This systematic review thematically analysed 113 publications identified through PubMed and Web of Science on cuproptosis mechanisms and their relevance to pancreatic diseases.
Neoadjuvant pamiparib plus abiraterone and androgen deprivation therapy for high-risk/very high-risk localized prostate cancer: an open-label, single-arm, phase 2 study.
This open-label, single-arm phase 2 study assessed four months of neoadjuvant pamiparib, abiraterone, and androgen deprivation therapy before prostatectomy in patients with high-risk or very high-risk localized prostate…
KRAS and MET Co-Mutation in One Lesion and EGFR Mutation in Another Lesion of Early-Stage Synchronous Multiple Lung Adenocarcinomas: A Case Report.
A 68-year-old man had three ground-glass opacities in the left upper lobe. After thoracoscopic left upper division segmentectomy, pathology showed synchronous early-stage lung adenocarcinomas with differing degrees of…
Systematic meta-analysis of the toxicities and side effects of the targeted drug lenvatinib.
This systematic review and meta-analysis assessed adverse events associated with lenvatinib in patients with cancer, synthesizing cohort studies and randomized controlled trials identified through December 31, 2024.
Identification of BAP1 Germline Mutation in a Pediatric Patient With Skull Base Meningioma.
An adolescent girl presented with a rare skull-base tumor whose imaging appearance suggested schwannoma. Testing for germline variants in NF2, LZTR1, and SMARCB1 was negative.
Immune thrombocytopenia triggered by dostarlimab in a patient with endometrial carcinoma: first reported case.
A 55-year-old woman receiving dostarlimab for relapsed endometrial carcinoma developed severe thrombocytopenia (3 × 10⁹/L) with rectal bleeding, creating a life-threatening presentation.
Reducing adverse effects in hypofractionated radiotherapy for prostate cancer: Clinical evidence and emerging mitigation strategies.
This systematic review examined toxicity outcomes and mitigation strategies in phase III trials comparing radiotherapy fractionation schedules for prostate cancer, including at least one hypofractionated arm.
Correlation between epigenetic modifier gene mutations and prognosis of patients with acute lymphoblastic leukemia: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed whether epigenetic modifier gene mutations are associated with survival in acute lymphoblastic leukemia (ALL).
Immunoglobulin M Multiple Myeloma: Case Report of a Rare Variant of Multiple Myeloma with Diagnostic and Treatment Challenges.
A 64-year-old woman presented with three weeks of persistent lower back pain. Testing showed anemia (hemoglobin 9.2 g/dL), an IgM level of 5,070 mg/dL, an M-spike of 3.09 g/dL, and monoclonal IgM lambda with an abnormal…
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