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1999 articles

September 202624

Clinical ResearchCardiology

Comparison of bivalirudin versus heparin in percutaneous coronary intervention for patients with acute coronary syndrome: A meta-analysis.

This meta-analysis compared bivalirudin and heparin in patients with acute coronary syndrome undergoing percutaneous coronary intervention, including 11 RCTs and 17 cohort studies with 584,249 patients.

Medicine (Baltimore)Sep 25, 2026Read summary
Case ReportGastroenterologyOpen access

A case report: an unusual case of ulcerative intestinal IgG4-related disease with clinical features overlapping with probable intestinal Behcet's disease.

A 62-year-old man with a history of recurrent oral ulcers presented with sudden hematochezia and hypovolemic shock. Imaging showed sclerosing mesenteritis, and endoscopy revealed multiple small intestinal ulcers.

BMC GastroenterolSep 25, 2026Read case
Clinical ResearchPsychiatryOpen access

The effect of dance movement therapy on traumatized refugee women - a clinical controlled trial.

This controlled clinical trial evaluated the effects of dance movement therapy (DMT) on 24 traumatized refugee women in Germany.

BMC Complement Med TherSep 25, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Effectiveness of digital interventions for menopausal symptoms and cardiometabolic outcomes among women undergoing the menopausal transition: A systematic review and meta-analyses.

This systematic review and meta-analysis assessed digital health interventions for menopausal symptoms and cardiometabolic outcomes in women undergoing the menopausal transition.

MaturitasSep 25, 2026Read summary
Clinical ResearchPediatricsOpen access

Increased ureagenesis revealing metabolic intolerance to enhanced nutrition in the PICU: a secondary analysis of the PEPaNIC RCT.

This secondary analysis of the PEPaNIC RCT evaluated the effects of early versus late parenteral nutrition (PN) in critically ill children (newborn-17 years) in PICUs.

Crit CareSep 25, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Outcomes of delayed CSF diversion protocol in Infants with lumbosacral myelomeningocele: impact of timing of presentation on hydrocephalus development and postoperative complications.

This controlled clinical trial evaluated the outcomes of a delayed cerebrospinal fluid (CSF) diversion protocol in 186 infants with lumbosacral myelomeningocele (MMC) across two centers in Iraq.

Childs Nerv SystSep 25, 2026Read summary
Case ReportNeurosurgeryOpen access

Fatal spontaneous bilateral extradural hematoma with swirl sign in a child with sickle cell disease: lessons from delayed surgical access at a tertiary center.

A 13-year-old girl with homozygous sickle cell disease presented with sudden altered consciousness and left hemiparesis, showing a Glasgow coma scale of 9.

Childs Nerv SystSep 25, 2026Read case
Clinical ResearchOphthalmologyOpen access

Efficacy and Safety of IGF-1 Receptor Inhibitors for Thyroid Eye Disease: Systematic Review and Meta-analysis of Randomized Controlled Trials.

This systematic review and meta-analysis pooled randomized controlled trials comparing IGF-1 receptor inhibitors with placebo for thyroid eye disease (TED).

DrugsSep 24, 2026Read summary
Clinical ResearchHematology

Expanded antigen-specific donor regulatory T cells for GVHD prevention.

This phase 1 clinical trial evaluated the safety and preliminary efficacy of expanded minor histocompatibility antigen (mHAg)-specific donor regulatory T cells (Treg) for preventing graft-versus-host disease (GVHD) in…

BloodSep 24, 2026Read summary
Case ReportOphthalmology

Corneal ectasia in ectodermal dysplasia: Novel Tumour Protein 63-related phenotype in Rapp-Hodgkin syndrome.

A man in his 20s with genetically confirmed Rapp-Hodgkin syndrome presented with progressive visual decline in the left eye over 12 months.

BMJ Case RepSep 24, 2026Read case
Clinical ResearchEmergency Medicine

AI Decision Support for Emergency Triage of Large Vessel Occlusion Using Noncontrast Computed Tomography: Systematic Review and Bayesian Diagnostic Test Accuracy Network Meta-Analysis.

This systematic review and Bayesian network meta-analysis evaluated the diagnostic accuracy of noncontrast computed tomography (NCCT)-based AI for detecting anterior circulation large vessel occlusion (LVO) compared to…

J Med Internet ResSep 24, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Birth outcomes following intrauterine exposure to electronic nicotine delivery systems: a systematic review and meta-analysis.

This systematic review and meta-analysis examined birth outcomes associated with intrauterine exposure to electronic nicotine delivery systems (ENDS) compared to non-exposed and other nicotine-exposed neonates.

Nicotine Tob ResSep 24, 2026Read summary
Clinical ResearchInternal Medicine (General)

Feasibility of an interdisciplinary primary care-based intervention to improve care transitions for hospitalized patients with substance use disorders: The IntACT pilot randomized controlled trial protocol.

The IntACT pilot study is a single-site randomized controlled trial assessing the feasibility and preliminary effectiveness of a primary care-based intervention for hospitalized patients with substance use disorders…

PLoS OneSep 24, 2026Read summary
Clinical ResearchNeurology

Brain-motor behavior coupling during walking while negotiating obstacle: A systematic review.

This systematic review examined cortical activity alongside gait during obstacle negotiation in adults, using a brain–motor behavior framework.

Neurosci Biobehav RevSep 24, 2026Read summary
Clinical ResearchCardiology

Survival benefit of guideline-directed medical therapy in older patients with heart failure: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the survival benefits of guideline-directed medical therapy (GDMT) in older patients (≥65 years) with heart failure and reduced ejection fraction (HFrEF).

HeartSep 24, 2026Read summary
Clinical ResearchHematology

Venetoclax plus pediatric regimen in adolescents and adults with Ph-negative acute lymphoblastic leukemia.

This phase II multicenter trial evaluated the efficacy of venetoclax combined with pediatric-inspired chemotherapy in 167 adolescents and adults with newly diagnosed Philadelphia chromosome-negative acute lymphoblastic…

BloodSep 24, 2026Read summary
Case ReportOncology (Medical)

Jejunal metastatic melanoma presenting with occult gastrointestinal haemorrhage and refractory anaemia.

An elderly man with a history of cutaneous melanoma presented with chronic iron-deficiency anemia and weight loss. Imaging and endoscopy failed to provide a definitive diagnosis, revealing only an aneurysmal jejunal…

BMJ Case RepSep 24, 2026Read case
Case ReportOrthopedic Surgery

Challenging Removal of Intramedullary Nails: Description of 2 Techniques With Proposal to Classify Nail Extraction Methods.

This report details two cases of intramedullary nail removal. The first involved an intact, incarcerated short proximal femoral nail successfully extracted without creating an additional bone window, followed by hip…

JBJS Case ConnectSep 24, 2026Read case
Clinical ResearchHematology

Etuvetidigene Autotemcel for the Treatment of Wiskott-Aldrich Syndrome.

This multicenter clinical trial evaluated the safety and efficacy of etuvetidigene autotemcel (etu-cel) in patients with Wiskott-Aldrich syndrome, integrating data from two studies and an expanded-access program.

N Engl J MedSep 24, 2026Read summary
Clinical ResearchNeurology

Efficacy of music-based telerehabilitation after stroke: protocol description of a randomised controlled trial.

This randomized controlled trial investigates the efficacy of a novel music-based telerehabilitation program for stroke recovery in 100 patients from Southern Finland.

BMJ OpenSep 24, 2026Read summary
Clinical ResearchHematology

Phase 1 Study of Anito-cel, a d-Domain BCMA CAR T Cell for Refractory or Recurrent Myeloma.

This phase 1 multicenter study evaluated the safety and efficacy of anitocabtagene autoleucel (anito-cel), a BCMA-directed CAR T-cell therapy, in 40 patients with relapsed or refractory multiple myeloma.

N Engl J MedSep 24, 2026Read summary
Case ReportOrthopedic Surgery

Anterior Interosseus Nerve Syndrome Masqueraded by a Functional Gantzer Muscle Variant: A Report of 3 Cases.

Three patients with anterior interosseous nerve syndrome (AINS) exhibited thumb interphalangeal flexion despite complete denervation of the flexor pollicis longus.

JBJS Case ConnectSep 24, 2026Read case
Case ReportOrthopedic Surgery

Radioulnar Synostosis After Isolated Undisplaced Distal Ulna Fracture: A Rare Case Report and Review of the Literature.

A 50-year-old man presented with restricted forearm rotation due to radioulnar synostosis, which developed 15 months after an isolated undisplaced distal ulna fracture.

JBJS Case ConnectSep 24, 2026Read case
Clinical ResearchHematology

Recurrent VTE in patients with thrombophilia after stopping anticoagulation: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the risk of recurrent venous thromboembolism (VTE) after stopping anticoagulation in patients with hereditary and acquired thrombophilia.

Blood AdvSep 24, 2026Read summary

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