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1999 articles
September 202624
Mitochondrial DNA methylation as a bridge: Linking indoor air purification to alleviated cardiovascular impairments in young adults.
This randomized, double-blind crossover trial examined whether mitochondrial DNA (mtDNA) methylation was associated with fine particulate matter (PM2.5) exposure and cardiovascular indicators in 38 healthy young adults.
18 F-THK5351 PET Findings Indicative of Reactive Astrogliosis in Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy.
A patient with autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) underwent 18F-THK5351 PET, 18F-FDG PET, and MRI.
One Tracer, Whole Syndrome: CAIX-Targeted PET Unmasks the Multisystem Tumor Landscape of Von Hippel-Lindau Disease.
A 50-year-old man with von Hippel–Lindau disease underwent multimodal imaging to assess residual central nervous system disease.
18 F-FET PET Pitfall in Pituitary Imaging: False-positive Uptake Due to Neurosarcoidosis.
A 38-year-old man with previously treated pulmonary sarcoidosis underwent pituitary imaging. MRI showed a left-sided pituitary neuroendocrine tumor (PitNET), whereas 18F-FET PET/CT showed uptake on both sides, with…
18F-FDG PET/CT Manifestations of a Gastrointestinal Stromal Tumor Presenting With Predominant Hepatic and Peritoneal Metastases.
A 70-year-old man presented with abdominal pain. Contrast-enhanced CT demonstrated multiple large space-occupying lesions in the liver.
Giant Well-Differentiated Liposarcoma of the Spermatic Cord Associated With Inguinal Hernia: Clinical Insights From a Case Report.
An 87-year-old man presented with a progressively enlarging, painless mass in the left inguinoscrotal region, which impaired mobility.
Summer-pattern seasonal affective disorder: A case study and implications for primary care.
A 35-year-old woman presented with a 3-year history of summer-onset depression, characterized by irritability, insomnia, appetite loss, and psychomotor agitation.
Bridging the gap in caregiver support: A systematic review of screening practices in primary care.
This systematic review examined the use of caregiver burden screening practices in primary care, focusing on studies from 2013 to 2023.
Structured exercise interventions and survival outcomes in patients with cancer: systematic review and meta-analysis of randomised controlled trials.
This systematic review and meta-analysis evaluated the impact of structured exercise interventions on survival outcomes in cancer patients.
A case of membranous nephropathy during asymptomatic syphilis.
A 51-year-old woman presented with weight gain and leg edema, leading to a diagnosis of nephrotic syndrome. Laboratory tests revealed low serum protein and heavy proteinuria.
Population pharmacokinetic analysis of pirtobrutinib, a non-covalent BTK inhibitor, in patients with hematological malignancies from the Phase 1/2 BRUIN study.
This population pharmacokinetic analysis evaluated pirtobrutinib, a non-covalent BTK inhibitor, in 595 patients with hematological malignancies from the Phase 1/2 BRUIN study.
Primary Hyperparathyroidism Presenting as a Distal Femur Pathologic Fracture in an Adolescent: A Case Report.
A 17-year-old boy presented with a pathologic fracture of the distal femur, accompanied by bilateral distal femoral metadiaphyseal lytic lesions.
Association of androgen deprivation therapy and acute kidney injury in patients with prostate cancer: a systematic review and meta-analysis of 72,980 patients.
This systematic review and meta-analysis evaluated the association between androgen deprivation therapy (ADT) and acute kidney injury (AKI) in 72,980 prostate cancer patients.
Salvaging a submental flap.
A 50-year-old man underwent surgery for carcinoma of the gingivobuccal sulcus, followed by reconstruction using a submental artery-based island flap (SMIF).
Osteosarcoma of the Maxilla: Rare Contralateral Cervical Lymph Node Metastasis.
A patient with osteosarcoma of the maxilla presented with contralateral cervical lymph node metastasis following surgical intervention.
Parental awareness, attitudes and decision-making of off-label use in children: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated parental awareness and attitudes towards off-label medication use in children. In seven studies, the pooled parental awareness rate was found to be 20.2%.
Red blood cell transfusion to treat or prevent complications in sickle cell disease: an overview of Cochrane reviews.
This systematic review and meta-analysis evaluated the efficacy of red blood cell (RBC) transfusions in treating or preventing complications in sickle cell disease (SCD) across 17 Cochrane reviews.
Comparison of Robotic-Assisted Versus Conventional Total Knee Arthroplasty: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the clinical and radiological outcomes of robotic-assisted total knee arthroplasty (RTKA) compared to conventional total knee arthroplasty (CTKA) across 52 studies.
Zuclopenthixol acetate for acute schizophrenia and similar major mental illnesses.
This systematic review and meta-analysis evaluated the effectiveness of zuclopenthixol acetate for managing acute behavioral disturbances in 714 participants with acute schizophrenia and similar major mental illnesses.
Effect of Continuous Positive Airway Pressure on Left Atrial Volume Index in Patients With Stroke and Obstructive Sleep Apnea: A Randomized Trial.
This randomized trial evaluated whether continuous positive airway pressure (CPAP) altered left atrial volume index (LAVI) in patients with stroke and obstructive sleep apnea.
Extraneural ganglion cyst causing foot drop.
A male in his late 50s presented with a swelling on the lateral aspect of the right proximal lower leg, accompanied by progressive ankle dorsiflexion weakness and sensory loss on the dorsum of the foot.
Clinical Outcomes of Left Atrial Appendage Occlusion During Cardiac Surgery in Patients Without Atrial Fibrillation: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis combined randomized and observational studies comparing surgical left atrial appendage occlusion (LAAO) with no occlusion during cardiac surgery in patients with sinus rhythm and…
Clinical and Molecular Delineation of KAT6B -Related Disorders: Novel Variants and Refined Genotype-Phenotype Correlations.
KAT6B-related disorders (KRDs) comprise a spectrum of developmental disorders ranging from Genitopatellar syndrome (GPS) to Say-Barber-Biesecker-Young-Simpson syndrome (SBBYSS), with increasing recognition of…
Clinical Surveillance Technologies in Nonintensive Care Unit Hospital Settings: Systematic Review and Bayesian Network Meta-Analysis of Randomized Trials.
This systematic review and Bayesian network meta-analysis evaluated the clinical effects of rule-based electronic surveillance (RB-ES), predictive model-based electronic surveillance (PM-ES), and continuous physiologic…
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