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433 articles

September 202612

Case ReportHematology

Systemic amyloidosis diagnosed by labial salivary gland biopsy.

A man in his 60s presented with acute decompensating heart failure and was initially evaluated for cardiac amyloidosis. Due to difficulties in obtaining a tissue sample, he was referred for a labial salivary gland…

BMJ Case RepSep 1, 2026Read case
Clinical ResearchHematologyOpen access

Cardiovascular disease and amyloidosis in phase III multiple myeloma trials: a systematic review of eligibility, screening and event reporting.

This systematic review evaluated phase III randomized controlled trials of multiple myeloma therapies, focusing on eligibility criteria related to cardiovascular disease (CVD) and amyloidosis.

Open HeartSep 1, 2026Read summary
Case ReportHematology

Case Report and Retrospective Review of Acanthamoeba Encephalitis and Chronic Lymphocytic Leukemia, United States.

A patient with chronic lymphocytic leukemia (CLL) presented with Acanthamoeba encephalitis. The case highlights the association between CLL and Acanthamoeba infections, noting that CLL is the most common underlying…

Emerg Infect DisSep 1, 2026Read case
Case ReportHematology

Neoehrlichiosis Causing Hemolytic Anemia in Patients Treated with Rituximab, Norway, 2024-2025.

Three rituximab-treated patients in Norway presented with direct antiglobulin test-negative hemolytic anemia due to Neoehrlichia mikurensis infection.

Emerg Infect DisSep 1, 2026Read case
Clinical ResearchHematologyOpen access

A Phase 1 Trial of Duvelisib and Oral Azacitidine in Relapsed/Refractory T-Cell Lymphoma.

This Phase I trial evaluated the combination of duvelisib and oral azacitidine in 14 patients with relapsed/refractory T-cell lymphoma.

Hematol OncolSep 1, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Convalescent Plasma Restores Viral Clearance After Anti-Spike Monoclonal Antibody Failure in Immunocompromised COVID-19 Patients: A Systematic Review and Meta-Analysis of Individual Patient Data.

This systematic review and meta-analysis evaluated the effectiveness of convalescent plasma (CCP) in immunocompromised COVID-19 patients who remained positive for SARS-CoV-2 after anti-Spike monoclonal antibody (mAb)…

Rev Med VirolSep 1, 2026Read summary
Case ReportNeurologyOpen access

Amyloid-Like Immunoglobulin Deposition Neuropathy.

A case of amyloid-like immunoglobulin deposition neuropathy was presented, characterized by predominant neuropathic pain, skin changes, and progressive distal sensory neuropathy.

J Peripher Nerv SystSep 1, 2026Read case
Case ReportHematologyOpen access

Type 1 Diabetes Driven by Residual Recipient T Cells After Hematopoietic Cell Transplantation: A Case Report.

A patient developed type 1 diabetes following haploidentical hematopoietic cell transplantation. Analysis revealed an expanded population of islet-specific CD4+ T cells in the recipient, predominantly restricted by…

Diabetes CareSep 1, 2026Read case
Clinical ResearchEndocrinologyOpen access

Iron overload disorders in adults: a comprehensive review of gonadal function, reproductive, and sexual health.

This systematic review examined gonadal function, fertility, sexual health, and pregnancy outcomes in adults with iron overload disorders, including thalassaemias, hereditary haemochromatosis, and transfusion-dependent…

Hum Reprod UpdateSep 1, 2026Read summary
Case ReportHematology

Wartime Occurrence of Severe Aplastic Anemia in Previously Healthy Military Service Members: A Case Series.

Three previously healthy military service members developed idiopathic severe aplastic anemia (SAA) during active duty, presenting with cytopenias and hemorrhagic symptoms.

Mil MedSep 1, 2026Read case
Case ReportMedical Genetics

Tandem Double Inversion Resolves the Structural Paradox Underlying Recurrent KAT6A::NCOA2 Fusion in Acute Myeloid Leukemia.

A case of acute myeloid leukemia (AML) presented with the rare KAT6A::NCOA2 fusion, typically associated with inv(8)(p11q13). Genomic profiling revealed an unexpected MTFR1::KAT6A rearrangement.

Genes Chromosomes CancerSep 1, 2026Read case
Clinical ResearchHematologyOpen access

XY0206 targets FLT3-dependent resistance states in acute myeloid leukemia.

This phase I/II clinical trial evaluated XY0206 monotherapy in patients with relapsed or refractory acute myeloid leukemia (AML), alongside laboratory and animal studies of its FLT3-directed activity.

J Clin InvestSep 1, 2026Read summary

August 202612

Case ReportHematologyOpen access

Efficacy and Safety of Ropeginterferon Alfa-2b in Pregnant Women With Myeloproliferative Neoplasms: Case Series of Three Subtypes and Review.

This case series reports on four pregnancies in women with myeloproliferative neoplasms (MPNs), including prefibrotic myelofibrosis, essential thrombocythemia, and polycythemia vera.

J Korean Med SciAug 31, 2026Read case
Case ReportMedical Genetics

Clinical features, genetic analysis, and efficacy evaluation of hematopoietic stem cell transplantation in a case of osteopetrosis caused by compound heterozygous variations in the TNFRSF11A gene: a case study.

A three-year-old Chinese girl with osteopetrosis presented with recurrent fractures, short stature, and macrocephaly. Radiological findings showed elevated bone mineral density and constricted medullary spaces.

Croat Med JAug 31, 2026Read case
Clinical ResearchHematology

Phase II Study of Posttransplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis After HLA-Mismatched Unrelated Donor Reduced Intensity Transplantation: Results From the ACCESS Trial Expansion Cohort.

This prospective, multicenter phase II study evaluated posttransplant cyclophosphamide (PTCy)-based graft-versus-host disease prophylaxis in adults receiving peripheral blood stem cell transplantation from…

Am J HematolAug 31, 2026Read summary
Case ReportHematology

VEXAS Syndrome:Report of One Case.

An elderly male presented with fatigue and fever, later developing macrocytic anemia, tracheal and bronchial wall thickening, polyarthritis, rashes, and elevated inflammatory markers.

Zhongguo Yi Xue Ke Xue Yuan Xue BaoAug 30, 2026Read case
Clinical ResearchCardiology

Prothrombin complex concentrate (PCC) vs. non-PCC strategies for warfarin reversal in left ventricular assist device recipients: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated prothrombin complex concentrate (PCC) versus non-PCC strategies for warfarin reversal in left ventricular assist device (LVAD) recipients.

Intensive Crit Care NursAug 29, 2026Read summary
Case ReportHematology

Successful treatment of refractory hemophagocytic lymphohistiocytosis complicating Epstein-Barr virus-positive classic Hodgkin lymphoma with rituximab.

A male in his early 70s with advanced EBV-positive mixed-cellularity classic Hodgkin lymphoma presented with cervical lymphadenopathy, fever, and hepatosplenomegaly.

J Clin Exp HematopAug 29, 2026Read case
Case ReportInfectious Diseases

Severe Plasmodium falciparum malaria with marked ADAMTS13 reduction and secondary microangiopathic features: A case report.

A 46-year-old man returning from Nigeria presented with severe Plasmodium falciparum malaria after 11 days of intermittent fever, jaundice, and dark urine.

J Infect ChemotherAug 28, 2026Read case
Clinical ResearchHematologyOpen access

Prevalence and Clinical Relevance of Antiphospholipid Antibodies in Ischemic Stroke: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined the prevalence of antiphospholipid antibodies (aPL) in patients with ischemic stroke. Among 9438 patients, the pooled prevalence of aPL seropositivity was 19.1%.

StrokeAug 28, 2026Read summary
Clinical ResearchHematology

HOPE Kids 2: Phase 3, Randomized Trial of Voxelotor in Children With SCD and Conditional Cerebral Blood Flow Velocities.

HOPE Kids 2 was a phase 3, multicenter, double-blind, placebo-controlled randomized trial of voxelotor in children aged 2 to <15 years with sickle cell disease (HbSS/HbSβ⁰) and conditional cerebral blood flow velocities…

Am J HematolAug 28, 2026Read summary
Case ReportPediatrics

Long-Term Restoration of Anticoagulant Function After Liver Transplantation for Severe Congenital Protein C Deficiency: A Single-Center Experience Involving Three Pediatric Patients.

Three pediatric patients with severe congenital protein C deficiency underwent liver transplantation, resulting in plasma protein C activity levels exceeding 64% post-surgery.

Pediatr Blood CancerAug 27, 2026Read case
Clinical ResearchHematology

Risk factors for invasive yeast infections in adult patients with hematological malignancies and/or stem cell transplant: systematic literature review and meta-analysis.

This systematic review and meta-analysis examined risk factors for invasive yeast infections (IYI) in adults with hematological malignancies or undergoing hematopoietic stem cell transplantation.

Int J Infect DisAug 27, 2026Read summary
Clinical ResearchHematology

Effect of adding umbilical cord blood derived stem cells to haploidentical stem cell transplant (haplo-cord) on post-transplant survival and graft-versus-host disease in patients with hematological malignancies: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of adding umbilical cord blood-derived stem cells to haploidentical stem cell transplantation (haplo-cord) in patients with hematological malignancies.

Transpl ImmunolAug 26, 2026Read summary

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