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1316 articles

October 202624

Clinical ResearchOncology (Medical)Open access

Digital supportive care in prostate cancer: a systematic review.

This systematic review synthesised evidence on the perspectives and requirements of people affected by prostate cancer for patient-facing digital supportive care.

Support Care CancerOct 17, 2026Read summary
Clinical ResearchNeurologyOpen access

Global cognitive and verbal episodic memory impairment in the post-acute phase of anti-nmdar encephalitis: a systematic review and meta-analysis with narrative synthesis.

This systematic review and meta-analysis examined standardized cognitive outcomes in adults with cell-based-assay-confirmed anti-NMDAR encephalitis during the post-acute or convalescent phase.

Neurol SciOct 17, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Periconceptional and early-pregnancy exposure to SGLT2 inhibitors and congenital malformations: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis assessed observational cohort evidence on preconception or early-pregnancy SGLT2 inhibitor exposure among women with type 2 diabetes.

EndocrineOct 17, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Reducing period poverty through interventions, innovations, policies and multilevel barriers and facilitators: A systematic review.

This systematic review synthesised evidence on menstrual health interventions, innovations, policies, and barriers and facilitators related to period poverty in low-, middle-, and high-income countries.

Glob Public HealthOct 17, 2026Read summary
Clinical ResearchNeurologyOpen access

Genetic correlates of corticobasal degeneration: a systematic review and meta-analysis.

This PRISMA-guided systematic review and meta-analysis synthesized genetic association studies of corticobasal degeneration (CBD), including 22 studies published between 2001 and 2025.

J NeurolOct 17, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Effectiveness of local ablative therapy combined with first-line tyrosine kinase inhibitors in epidermal growth factor receptor-mutated oligometastatic non-small cell lung cancer: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed local ablative therapy (LAT) plus first-line tyrosine kinase inhibitors (TKIs) versus TKI alone in patients with EGFR-mutated oligometastatic non-small cell lung cancer.

Clin Exp MetastasisOct 17, 2026Read summary
Clinical ResearchRadiology (Diagnostic)Open access

Atypical Stafne bone defect: a systematic review.

This systematic review synthesized English-language case reports and case series of atypically located Stafne bone defects (SBDs), searching four databases through January 2026.

Clin Oral InvestigOct 17, 2026Read summary
Clinical ResearchOrthopedic Surgery

Patient-Reported Outcomes after Distal Radius Fractures Differ Across Geographic and Cultural Populations: A Global Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis examined whether patient-reported outcomes after volar locking-plate fixation of adult distal radius fractures varied across cultural and geographic populations.

J Orthop TraumaOct 17, 2026Read summary
Clinical ResearchPulmonologyOpen access

The Impact of Ambient Ozone Exposure on Respiratory Health in the U.S. Populations: A Systematic Review.

This systematic review synthesized U.S. epidemiologic and experimental studies published from 1980 to 2026 on acute and chronic ambient ozone exposure and respiratory health.

Curr Environ Health RepOct 17, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Systematic review and meta-analysis on comparing treatment approaches of cervical fractures in ankylosing spondylitis to determine improvement in outcomes.

This systematic review and meta-analysis compared anterior, posterior, and combined surgical approaches for cervical fractures in patients with ankylosing spondylitis.

Neurosurg RevOct 17, 2026Read summary
Clinical ResearchHematology

Non-Relapse Mortality With Bispecific Antibodies in Hematologic Malignancies: A Dual Systematic Review and Pharmacovigilance Analysis.

This systematic review and meta-analysis, supplemented by a pharmacovigilance analysis of FAERS, assessed non-relapse mortality (NRM) and other toxicities with bispecific antibodies in relapsed/refractory hematologic…

Hematol OncolOct 17, 2026Read summary
Clinical ResearchPediatricsOpen access

Pulpotomy of deciduous molars with deep caries using three different hydraulic calcium silicate cements: a short-term pilot randomized controlled split-mouth study.

This short-term pilot randomized controlled split-mouth study compared three hydraulic calcium silicate cements for pulpotomy in carious primary molars of children aged 2–6 years treated under general anesthesia.

Clin Oral InvestigOct 17, 2026Read summary
Clinical ResearchOncology (Medical)

Three traditional Chinese patent medicines combined with transarterial chemoembolization for primary liver cancer: A systematic review and Bayesian network meta-analysis.

This systematic review and Bayesian network meta-analysis assessed three traditional Chinese patent medicines combined with transarterial chemoembolization (TACE) for primary liver cancer.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchEmergency Medicine

Neutrophil to lymphocyte ratio for predicting delayed neurologic sequelae caused by carbon monoxide poisoning: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether the neutrophil-to-lymphocyte ratio (NLR) predicts delayed neurologic sequelae (DNS) after acute carbon monoxide poisoning.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Effectiveness of different autologous platelet concentrates for orthodontic canine retraction following premolar extraction: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed platelet-rich plasma (PRP), injectable platelet-rich fibrin (i-PRF), and leukocyte-platelet-rich fibrin (L-PRF) for accelerating orthodontic canine retraction after…

Prog OrthodOct 16, 2026Read summary
Clinical ResearchMedical Genetics

The extra X chromosome and autoimmune susceptibility in Klinefelter syndrome.

This systematic review and meta-analysis assessed autoimmune susceptibility in people with Klinefelter syndrome (47,XXY), using studies of autoimmune disease and serological markers.

J Clin Endocrinol MetabOct 16, 2026Read summary
Clinical ResearchOncology (Medical)

Impact of Phosphatidylinositol 3-Kinase and B-Raf Mutations in Rat Sarcoma Wild-Type Metastatic Colorectal Cancer.

This systematic review and meta-analysis assessed whether PIK3CA and BRAF mutations were associated with outcomes among patients with RAS wild-type metastatic colorectal cancer receiving first-line EGFR inhibitor…

J Vis ExpOct 16, 2026Read summary
Clinical ResearchEndocrinology

Retatrutide and lipid and metabolite profiles in participants with obesity with or without type 2 diabetes.

This post hoc exploratory analysis of two randomized, placebo-controlled phase 2 trials examined fasting plasma metabolite and lipid changes with retatrutide in participants with obesity, with or without type 2…

J Clin Endocrinol MetabOct 16, 2026Read summary
Clinical ResearchNephrology

Local ancestry-aware genome-wide meta-analysis uncovers novel genetic loci for sickle cell disease nephropathy.

This local ancestry-aware genome-wide association meta-analysis examined estimated glomerular filtration rate in participants from two well-characterized adult sickle cell disease cohorts, seeking genetic loci…

Blood AdvOct 16, 2026Read summary
Clinical ResearchNephrology

Peritoneal catheter fixation versus nonfixation in open surgery: A meta-analysis.

This meta-analysis compared fixation with nonfixation of peritoneal dialysis (PD) catheters placed by open surgery. Thirteen studies included 648 patients in the fixation group and 627 in the nonfixation group.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchCardiology

Chios Mastic in Well-Controlled Hypertension: Findings From the HYPER-MASTIC Randomized Controlled Trial.

This double-blind, randomized, placebo-controlled trial assessed whether Chios mastic provides additional cardiovascular benefits in 106 adults with stable, well-controlled hypertension.

Pharmacol Res PerspectOct 16, 2026Read summary
Clinical ResearchPulmonology

The effects of multiregional fascial mobilization on heart rate and physiological parameters in patients with obstructive sleep apnea: A randomized controlled trial.

This randomized controlled trial assessed the acute physiological effects of a 16-minute multiregional fascial mobilization protocol in 95 men with polysomnography-confirmed moderate-to-severe obstructive sleep apnea.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchNeurology

Repetitive transcranial magnetic stimulation for the treatment of restless legs syndrome: A meta-analysis.

This meta-analysis examined repetitive transcranial magnetic stimulation (rTMS) versus sham stimulation for restless legs syndrome (RLS), pooling four eligible studies.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Vacuum-Assisted Breast Biopsy and Excision for Breast Lesions: A Systematic Review and Meta-analysis of Malignant Upgrade in B3 Lesions.

This systematic review and meta-analysis examined malignant upgrade in B3 breast lesions assessed through diagnostic vacuum-assisted biopsy (VAB/VABB) or second-line vacuum-assisted excision (VAE).

J Vis ExpOct 16, 2026Read summary

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