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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

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FeaturedClinical ResearchNeurology

Intensive blood pressure lowering after spontaneous intracerebral haemorrhage for secondary stroke prevention (RECAP-ICH): a systematic review and individual participant data meta-analysis.

Lancet NeurolSep 1, 2026

This systematic review and individual participant data meta-analysis evaluated the effects of intensive blood pressure-lowering treatment on recurrent stroke in 2944 adults with a history of spontaneous intracerebral…

Why it matters

The findings suggest that intensive blood pressure management can significantly reduce the risk of recurrent strokes in patients with a history of intracerebral haemorrhage, highlighting the importance of aggressive…

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Also worth knowing

Clinical ResearchCardiology

Complete Revascularization Guided by Functional Coronary Angiography in STEMI.

This randomized controlled trial evaluated the effectiveness of complete coronary-artery revascularization guided by functional coronary angiography versus conventional angiography in patients with STEMI and multivessel…

N Engl J MedAug 29, 2026Read summary
Clinical ResearchNephrology

Effect of intradialytic exercise on cardiovascular structural and functional parameters in maintenance haemodialysis: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effects of intradialytic exercise (IDE) on cardiovascular parameters in patients undergoing maintenance haemodialysis (MHD).

BMJ OpenSep 9, 2026Read summary
Clinical ResearchCardiology

Comparative efficacy of LDL-C-lowering therapies in first-time vs. recurrent myocardial infarction prevention: a meta-analysis of large-scale randomized controlled trials.

This meta-analysis evaluated the efficacy of LDL-C-lowering therapies in preventing first-time versus recurrent myocardial infarction (MI) across 22 randomized controlled trials involving 180,304 participants.

Eur J Prev CardiolSep 4, 2026Read summary
Clinical ResearchCardiology

Prehabilitation for patients with mild to moderate frailty undergoing coronary artery and valve surgery: a pilot randomized controlled trial.

This pilot randomized controlled trial evaluated a frailty-specific prehabilitation program for adult patients with mild to moderate frailty undergoing elective coronary or valve surgery.

Eur J Cardiovasc NursSep 8, 2026Read summary
Clinical ResearchCardiology

Patient-reported barriers to dietary adherence in heart failure: a qualitative substudy of the Pro-HEART trial.

This qualitative substudy of the Pro-HEART randomized controlled trial examined barriers to dietary adherence in 24 participants with heart failure during a 12-week weight-loss phase.

Eur J Cardiovasc NursSep 8, 2026Read summary
Clinical ResearchCardiology

Beyond the Liver: Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) Associated 35% Higher Risk of Clinically Diagnosed Heart Failure With Preserved Ejection Fraction (HFpEF).

This systematic review and meta-analysis examined the association between metabolic dysfunction-associated steatotic liver disease (MASLD) and heart failure with preserved ejection fraction (HFpEF) in a population of…

Curr Cardiol RepSep 9, 2026Open accessRead summary
Clinical ResearchPulmonology

Comorbidities in clinical cohorts of patients with idiopathic pulmonary fibrosis: a systematic review and meta-analysis.

This systematic review and meta-analysis examined the prevalence and impact of comorbidities in 606,398 patients with idiopathic pulmonary fibrosis (IPF).

Eur Respir RevSep 9, 2026Read summary
Clinical ResearchNephrology

Dapagliflozin and Acute Kidney Injury Following Cardiac Surgery: A Randomized Clinical Trial.

This multicenter, double-blind, placebo-controlled randomized clinical trial evaluated the effect of dapagliflozin on acute kidney injury (AKI) in 784 adults undergoing elective cardiac surgery.

JAMASep 1, 2026Open accessRead summary
Clinical ResearchCardiology

A remote booster program to attenuate sedentary behaviour in patients with coronary artery disease: a randomized controlled trial.

This randomized controlled trial evaluated a 3-week remote booster intervention aimed at reducing sedentary time (ST) in patients with coronary artery disease (CAD) who had completed cardiac rehabilitation.

Eur J Prev CardiolSep 8, 2026Read summary
Clinical ResearchCardiology

Prognostic significance of stress hyperglycemia ratio in patients undergoing percutaneous coronary intervention: a dose-response meta-analysis.

This meta-analysis evaluated the prognostic significance of the stress hyperglycemia ratio (SHR) in 41,096 patients undergoing percutaneous coronary intervention (PCI).

BMJ Open Diabetes Res CareAug 31, 2026Open accessRead summary
Clinical ResearchCardiology

Sex differences in computed tomography-derived fractional flow reserve-guided management of stable coronary artery disease: a subgroup analysis of the TARGET trial.

This post hoc analysis of the TARGET trial examined sex differences in treatment outcomes for 1,216 patients with stable coronary artery disease (CAD) receiving either CT-FFR-guided care or standard care.

EuroInterventionSep 7, 2026Read summary

Showing 12 of 75 publications that cleared our clinical screen in the last 14 days.

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