Trending Now

Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

AllClinical ResearchCase Reports
FeaturedCase ReportDermatology

5-Aminolevulinic acid-based photodynamic therapy used as a long-term management approach for refractory lichen sclerosus.

J Dermatolog TreatOct 21, 2026

A 37-year-old man with more than 10 years of genital lichen sclerosus had recurrence after surgical resection, which left permanent anatomical deformity.

Clinical pearl

In this case, recurrence followed discontinuation of ALA-PDT, while lesions regressed after subsequent courses; the reported response therefore occurred with repeated treatment rather than a single course.

Read case

Also worth knowing

Case ReportDermatologyOpen access

Inherited epidermal differentiation disorders (EDD) in pediatric patients from a single Italian referral Center.

A retrospective review at an Italian referral center described three children with congenital, clinically heterogeneous inherited epidermal differentiation disorders.

Eur J PediatrOct 21, 2026Read case
Case ReportDermatologyOpen access

Blood, ink, and flies: A case report on the house fly (Musca domestica) feeding on active tattooing wounds.

During a tattoo session, a healthy 32-year-old man in Germany experienced repeated landing and feeding attempts by house flies on freshly wounded skin of his right lower leg.

Parasitol ResOct 21, 2026Read case
Case ReportDermatology

Isolated Bilateral Periocular Lupus Miliaris Disseminatus Faciei: A Clinicopathological Mimicker of Granulomatosis With Polyangiitis.

A healthy young adult man presented with symmetrical papules confined to both periocular regions. Eyelid biopsy showed suppurative necrotizing granulomatous inflammation, prompting concern for granulomatosis with…

Am J Case RepOct 19, 2026Read case
Case ReportDermatology

Oral mucous membrane pemphigoid as a window to systemic autoimmunity: two cases associated with rheumatoid arthritis and Sjögren's disease.

Two women presented with oral mucous membrane pemphigoid (MMP) in the setting of systemic autoimmunity. A 68-year-old woman with longstanding rheumatoid arthritis had recurrent oral ulcerations confirmed as MMP on…

Einstein (Sao Paulo)Oct 19, 2026Read case
Case ReportDermatologyOpen access

Focal Epithelial Hyperplasia in a Somali Child: A Case Report and Review of Management with Topical Imiquimod.

An 8-year-old Somali girl had a 3.5-year history of asymptomatic, progressively increasing oral lesions. Examination showed multiple soft, flat-topped verrucous papules on the lower labial, buccal and lingual mucosa and…

Int Med Case Rep JOct 15, 2026Read case
Case ReportEndocrinology

Approach to the patient with APS-1/APECED.

This article presents five cases of autoimmune polyendocrine syndrome type 1 (APS-1/APECED), a disorder caused by impaired immune tolerance and typically associated with biallelic AIRE variants.

J Clin Endocrinol MetabOct 16, 2026Read case
Case ReportDermatology

Tranilast/roxithromycin with topical tacrolimus in refractory atopic facial eczema: Case report.

A 30-year-old man with atopic dermatitis had facial eczema and severe itching that persisted despite conventional treatment, including oral betamethasone.

Int J Clin Pharmacol TherOct 16, 2026Read case
Case ReportDermatologyOpen access

Exploring the landscape of flagellate erythema as a rare cutaneous symptom of idiopathic inflammatory myopathy: a case series-based review.

Two patients with idiopathic inflammatory myopathy developed zebra-like flagellate erythema: one had immune-mediated necrotising myopathy and the other anti-Mi-2-positive cancer-associated myositis.

Rheumatol IntOct 14, 2026Read case
Looking for an earlier article?Everything that has appeared in Trending is in the archive.

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text
Create my personalized digestSee plans

Prefer listening? Personalized audio digests are available with Pro.