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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

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FeaturedClinical ResearchEmergency Medicine

A multifaceted intervention to increase bystander CPR rates after out-of-hospital cardiac arrest in France: a stepped-wedge, cluster-randomised, controlled trial.

Lancet Public HealthOct 21, 2026

This stepped-wedge, cluster-randomised controlled trial assessed a coordinated intervention to increase bystander CPR before EMS arrival among adults with non-traumatic out-of-hospital cardiac arrest in France.

Why it matters

Bystander CPR is an important early response to OHCA, and this trial suggests that combining dispatcher support, volunteer activation, and agency feedback can increase its use.

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Also worth knowing

Clinical ResearchNeurologyOpen access

Tenecteplase, alteplase, and endovascular thrombectomy in extended-window acute ischemic stroke with intracranial large-vessel occlusion: a Bayesian network meta-analysis.

This Bayesian network meta-analysis compared reperfusion strategies in imaging-selected patients with acute ischemic stroke treated 4.5 to 24 hours after onset or last known well.

J NeurolOct 16, 2026Read summary
Clinical ResearchNeurologyOpen access

Prediction of death by neurologic criteria in patients with non-traumatic acute brain injury: a systematic review and meta-analysis.

This systematic review and meta-analysis examined predictors of death by neurologic criteria (DNC) after non-traumatic acute brain injury.

BMC NeurolOct 22, 2026Read summary
Clinical ResearchEmergency Medicine

Technological Integration in Triage With AI and Machine Learning Compared With Conventional Triage and Narrative Synthesis of Telehealth for Patient Prioritization in Emergency and Acute Care Settings: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed AI- and machine-learning-assisted triage alongside tele-triage and digital tools in emergency and acute care.

J Med Internet ResOct 19, 2026Read summary
Clinical ResearchEmergency Medicine

Neutrophil to lymphocyte ratio for predicting delayed neurologic sequelae caused by carbon monoxide poisoning: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether the neutrophil-to-lymphocyte ratio (NLR) predicts delayed neurologic sequelae (DNS) after acute carbon monoxide poisoning.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Acute management of pelvic ring injuries: identifying common treatment principles across institutional algorithms.

This PRISMA-guided systematic review compared published institutional algorithms for acute pelvic ring injury management. Searches identified 25 studies describing algorithms, pathways, or protocols published from 2006…

Eur J Orthop Surg TraumatolOct 16, 2026Read summary
Clinical ResearchEmergency Medicine

POCUS Image Archiving in Emergency Medicine: A Systematic Review of Clinical and Financial Impacts.

This systematic review assessed clinical, operational, and financial outcomes of archiving point-of-care ultrasound (POCUS) images in electronic health records in emergency departments.

Ultrasound QOct 19, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Anxiety in patients with cancer and emergency department use: a systematic review.

This systematic review examined whether anxiety is associated with subsequent emergency department (ED) use among adults with cancer.

Support Care CancerOct 14, 2026Read summary
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