Trending archive
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1143 articles
October 202624
Stereotactic body radiation therapy for pancreatic cancer: evaluating its efficacy, safety, and future prospects: systematic review.
This systematic narrative review assessed stereotactic body radiation therapy (SBRT) for locally advanced pancreatic cancer, including patients unsuitable for surgery.
Cine Magnetic Resonance Imaging for Assessing Chest Wall Invasion in Lung Cancer: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated cine MRI for detecting chest wall invasion in lung cancer, using surgical and histopathologic findings as the reference standard.
Precancerous cervical lesions and associated factors among HIV-positive women in Southern and Eastern African countries: A systematic review and meta-analysis.
This systematic review and meta-analysis pooled evidence on precancerous cervical lesions (PCCL) and associated factors among women living with HIV in Southern and Eastern Africa.
Association between cancer cachexia and treatment-related adverse outcomes in patients with gastrointestinal cancers: a systematic review and meta-analysis.
This systematic review and meta-analysis examined cohort studies of cancer cachexia and treatment-related outcomes in patients with gastrointestinal cancers.
Protective effect of N-acetylcysteine on oxaliplatin-induced peripheral neuropathy in colorectal cancer: a randomized controlled trial.
This randomized controlled trial evaluated oral N-acetylcysteine (NAC) for preventing oxaliplatin-induced peripheral neuropathy in 46 patients with stage III or high-risk stage II colorectal cancer receiving adjuvant…
Extracorporeal photopheresis for the treatment of steroid-refractory immune related adverse events from immune checkpoint inhibitor therapy: a multi-center phase Ib/II clinical trial.
This prospective, single-arm, non-randomized phase Ib/II multicentre trial evaluated extracorporeal photopheresis (ECP) for steroid-refractory immune-related adverse events (irAEs) in 30 patients receiving immune…
Impact of remote management using patient-reported outcomes on pain and anxiety after breast biopsy: the BIO-PSY randomized controlled trial.
The BIO-PSY French, single-centre, open-label randomised controlled trial assessed whether remote patient-reported outcome (PRO) monitoring with tailored interventions improved pain and anxiety after breast biopsy.
Bolus-only versus bolus plus continuous infusion hydromorphone for refractory cancer pain: a prospective, multicenter, randomized noninferiority trial.
This prospective, multicenter, randomized noninferiority trial compared bolus-only patient-controlled intravenous hydromorphone analgesia with bolus plus continuous infusion in patients with refractory cancer pain.
Translational applications and clinical utility of organoids in ovarian cancer: a systematic review.
This systematic review synthesized 13 studies of patient-derived organoids (PDOs) in ovarian cancer, assessing feasibility, histological fidelity, and agreement between organoid drug sensitivity and clinical outcomes.
Concurrent administration of BCMA and GPRC5D CAR T cells for advanced multiple myeloma.
This phase 1 dose-escalation trial evaluated BCMA-directed CAR T-cell therapy MCARH125 alone or infused concurrently with GPRC5D-directed MCARH109 in patients with relapsed or refractory multiple myeloma.
Anbalcabtagene autoleucel (PD-1 and TIGIT knockdown CD19 CAR T-cell therapy) for relapsed or refractory LBCL: the CRC01-01 trial.
The multicenter phase 1/2 CRC01-01 trial evaluated anbalcabtagene autoleucel, a CD19 CAR T-cell therapy with PD-1 and TIGIT knockdown, in patients with relapsed or refractory large B-cell lymphoma.
The prognostic value of physical functioning on survival in patients with nonsmall cell lung cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis examined whether objectively measured physical functioning predicts survival in adults with nonsmall cell lung cancer (NSCLC), across surgical and nonsurgical treatment groups.
Interventions to increase participation in lung cancer screening programmes: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed interventions to improve informed choice and participation in low-dose CT lung cancer screening.
Feasibility and safety of an exercise-based prehabilitation intervention before cancer surgery: a pilot randomised controlled trial.
This single-centre pilot randomised controlled trial assessed the feasibility and safety of supervised aerobic prehabilitation before surgery in patients with breast, colorectal, or prostate cancer.
Effectiveness of cardiac resynchronization therapy in cancer therapy-related cardiac dysfunction: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis assessed cardiac resynchronization therapy (CRT) outcomes in patients with cancer therapy-related cardiac dysfunction (CTRCD).
The role of allogeneic hematopoietic stem cell transplantation in adults with mature T-cell lymphomas.
This Cochrane systematic review and meta-analysis assessed allogeneic stem cell transplantation (alloSCT) for adults with mature T-cell lymphomas (MTCL), as first-line or salvage treatment.
Meta-analysis of 990 EBV genomes identifies EBER2 SNP7048 and its interaction with HLA-A*11:01 driving nasopharyngeal carcinoma risk.
This meta-analysis examined whether EBV genetic variation and host genetics are associated with nasopharyngeal carcinoma (NPC) across endemic populations in Singapore, Hong Kong, and China’s Guangdong and Guangxi…
Neoadjuvant Therapy for Gastric Adenocarcinoma with Signet Ring Cells: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis assessed neoadjuvant chemotherapy followed by surgery versus upfront gastrectomy in adults with signet ring cell-containing gastric cancer.
Comparative perioperative and oncological outcomes of the da Vinci Xi versus Si robotic surgical systems in rectal cancer surgery: a systematic review and meta-analysis.
This systematic review and meta-analysis compared perioperative and oncological outcomes with da Vinci Xi versus Si systems in rectal cancer surgery.
Entinostat plus exemestane for hormone receptor-positive advanced breast cancer: long-term overall survival results from the EOC103A3101 randomized controlled trial.
This randomized controlled trial assessed long-term overall survival with entinostat plus exemestane versus placebo plus exemestane in 354 patients with hormone receptor-positive, HER2-negative advanced breast cancer…
Combination of oral fluoropyrimidines and EGFR-directed antibodies in frail patients with metastatic colorectal cancer: a systematic review.
This systematic review assessed phase II and III evidence for oral fluoropyrimidines combined with EGFR-directed antibodies in patients with RAS wild-type metastatic colorectal cancer, including those considered unfit…
Comparative efficacy of interventions for preventing chemotherapy-induced alopecia: a systematic review and network meta-analysis.
This systematic review and network meta-analysis compared preventive interventions for chemotherapy-induced alopecia in cancer patients, including 12 randomized trials with 736 participants and nine intervention groups.
Efficacy and safety of ifupinostat in relapsed or refractory diffuse large B-cell lymphoma: a multicenter, single-arm phase 2 study.
This multicenter, single-arm phase 2 study evaluated intravenous ifupinostat monotherapy in patients with relapsed or refractory diffuse large B-cell lymphoma after at least two prior systemic therapy lines.
Comparable efficacy of extraoral and intraoral photobiomodulation in preventing oral mucositis during high-dose methotrexate therapy in pediatric oncology: A single-blind randomized controlled trial.
This single-blind randomized controlled trial compared intraoral (IO) with extraoral (EO) photobiomodulation (PBM) to prevent oral mucositis in 155 children and adolescents receiving high-dose methotrexate for leukemia…
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