Trending archive
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182 articles
October 202614
Influence of capsular tension ring implantation on dynamic in vivo capsular apposition and intraocular lens behavior in highly myopic eyes.
This prospective randomized clinical trial assessed whether capsular tension ring (CTR) implantation affects capsular apposition and intraocular lens (IOL) behavior after cataract surgery in highly myopic eyes.
EVALUATING THE EFFICACY AND SAFETY OF TOPICAL DIFLUPREDNATE IN PATIENTS WITH CHRONIC CENTRAL SEROUS CHORIORETINOPATHY.
This pilot, open-label randomized controlled trial compared topical difluprednate, oral eplerenone, and observation in adults with chronic or relapsing central serous chorioretinopathy.
EFFICACY AND SAFETY OF SUBTHRESHOLD LASER IN PATIENTS WITH ACUTE CENTRAL SEROUS CHORIORETINOPATHY: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis assessed the efficacy and safety of subthreshold laser for acute central serous chorioretinopathy (CSC), including six randomized controlled trials with 401 participants.
ULTRAWIDE-FIELD COLOR FUNDUS IMAGES AND ARTIFICIAL INTELLIGENCE FOR DIAGNOSIS OF DIABETIC RETINOPATHY: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed artificial intelligence (AI) for diabetic retinopathy (DR) evaluation using ultrawide-field fundus images.
Association between rheumatic diseases and glaucoma risk: a systematic review and meta-analysis of 5.7 million individuals.
This systematic review and meta-analysis examined glaucoma occurrence and risk among people with rheumatic diseases (RD), drawing on 18 studies with 5,766,143 participants.
Cost-effectiveness of monotherapy and combination therapy for myopia control in Chinese children.
This network meta-analysis and decision-analytic Markov model assessed the cost-effectiveness of 16 myopia-control strategies for Chinese children and adolescents, modelling eight-year-old children over eight years.
Full-spectrum LED screen-bar lighting as an adjunct to artificial tears in visual display terminal-related dry eye: a randomized study.
This prospective, randomised, single-centre study assessed whether full-spectrum screen-bar lighting adds benefit to artificial tears in 66 participants with newly diagnosed visual display terminal-related dry eye and…
Comparative Efficacy and Safety of Systemic Immunomodulatory Therapies for Non-Infectious Uveitis: A Systematic Review With Pairwise and Network Meta-Analyses.
This systematic review and network meta-analysis compared systemic immunomodulatory therapies for non-infectious uveitis (NIU), including evidence from seven studies with 992 participants: six randomised trials and one…
USB-powered vs. self-heating warm compresses for meibomian gland dysfunction: A prospective randomized crossover clinical trial.
This prospective randomized crossover trial compared USB-powered and self-heating warm compresses in 15 adults aged 18–40 years with meibomian gland dysfunction and tear break-up time ≤10 s.
Oral eplerenone in first-episode acute central serous chorioretinopathy: results of a double-masked randomized trial.
This double-masked, randomized, placebo-controlled trial evaluated oral eplerenone in 44 patients with first-episode acute central serous chorioretinopathy (CSCR).
Dexamethasone versus triamcinolone acetonide for the management of postoperative inflammation following cataract surgery: A systematic review and meta-analysis.
This systematic review and meta-analysis compared dexamethasone with triamcinolone acetonide (TCA) for postoperative inflammation in adults undergoing phacoemulsification.
Optogenetic Therapy for Restoring Aspects of Visual Function.
This open-label clinical trial evaluated safety and visual-function outcomes after ganglion cell-directed optogenetic therapy in 10 participants with blindness from advanced retinitis pigmentosa.
Microperimetry Sensitivity Changes at the Functional Transition Zone and at the EZ Margins in X-Linked Retinitis Pigmentosa Treated With Gene Therapy.
This post-hoc analysis of the randomized Skyline trial examined how photoreceptor ellipsoid-zone (EZ) structure related to microperimetry sensitivity in eyes with X-linked retinitis pigmentosa treated with gene therapy.
Genotype-Phenotype Relationships in Patients Carrying Biallelic FDXR Pathogenic Variants-New Cases and Systematic Review.
Biallelic pathogenic FDXR variations were identified in 2017 as being responsible for sensorial neuropathies. The first reported patients suffered from auditory and optic sensorineural impairments (ANOA, MIM #617717).
September 202610
Comparative study on the clinical effectiveness of low-concentration cyclosporine eye drops in patients with dry eye disease.
This multicenter, randomized, double-blind Phase 2 trial evaluated the efficacy and safety of low-concentration cyclosporine eye drops (SCAI-001 0.01% and 0.02%) versus Restasis (0.05%) in patients with dry eye disease.
Nine-year ocular developmental outcomes after ranibizumab or laser treatment for zone II retinopathy of prematurity: follow-up of a randomized trial cohort.
This study followed a randomized trial cohort to assess 9-year ocular developmental outcomes in children treated with intravitreal ranibizumab (IVR) or laser photocoagulation (LP) for zone II retinopathy of prematurity…
Incidence of secondary intraocular lens implantation in school-aged children left aphakic to age 4.5 years in the Infant Aphakia Treatment Study.
This randomized clinical trial assessed the incidence of secondary intraocular lens (IOL) implantation in children left aphakic after unilateral congenital cataract surgery.
Optical quality in decentration of intraocular lenses: updated systematic review.
This systematic review evaluated the impact of intraocular lens (IOL) decentration on optical quality across various IOL designs, including monofocal, EDOF, multifocal, and toric lenses.
Impact of different intraocular pressures during cataract surgery on retinal perfusion in eyes with diabetic retinopathy: randomized clinical trial.
This randomized clinical trial investigated the effects of low (20 mm Hg) versus high (55 mm Hg) intraocular pressure during cataract surgery on retinal perfusion in patients with nonproliferative diabetic retinopathy.
Primary Orbital Melanoma: A Systematic Review of Clinical Characteristics, Management and Outcomes.
This systematic review evaluated clinical characteristics, management, and outcomes of 112 patients with histopathologically confirmed primary orbital melanoma (POM).
Efficacy and Safety of IGF-1 Receptor Inhibitors for Thyroid Eye Disease: Systematic Review and Meta-analysis of Randomized Controlled Trials.
This systematic review and meta-analysis pooled randomized controlled trials comparing IGF-1 receptor inhibitors with placebo for thyroid eye disease (TED).
SILICONE OIL MIGRATION DURING INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR INJECTIONS: A Review of Clinical Evidence and Factors Related to Transmission.
This systematic review evaluated the incidence and mechanisms of silicone oil droplet transmission during intravitreal anti-vascular endothelial growth factor injections.
EFFECTIVENESS AND SAFETY OF BIOSIMILAR ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR FOR RETINAL DISEASES: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness and safety of biosimilar antivascular endothelial growth factor (VEGF) compared to reference anti-VEGF injections for retinal diseases.
Preclinical and clinical evaluation of systemic danegaptide for the treatment of nonproliferative diabetic retinopathy.
This phase 1b clinical trial evaluated the safety and early efficacy of danegaptide, an oral medication, in patients with nonproliferative diabetic retinopathy (NPDR) and mild center-involved macular edema.
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