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134 articles

October 202610

Clinical ResearchNeurosurgery

Patterns and predictive factors of hearing loss following microvascular decompression for hemifacial spasm: a systematic review.

This systematic review and meta-analysis assessed the prevalence, patterns, and potential risk factors for hearing loss after microvascular decompression for hemifacial spasm.

Neurosurg RevOct 22, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Duration of single-agent perioperative antibiotic prophylaxis and postoperative meningitis after endoscopic endonasal skull base surgery: a systematic review and meta-analysis of 7,981 patients.

This systematic review and meta-analysis examined postoperative meningitis after endoscopic endonasal skull-base surgery in 7,981 patients across 14 studies using single-agent perioperative antibiotic prophylaxis.

Neurosurg RevOct 17, 2026Read summary
Clinical ResearchPediatrics

Sleep apnea-hypopnea in children: Evidence that Lize Tongqi decoction with acupuncture, moxibustion, and Xinwu acupoint stimulation is superior to standard Western treatment using montelucast/mometasone furoate.

This randomized controlled trial compared a combined traditional Chinese medicine and acupuncture-based regimen with montelukast plus mometasone in 60 children with snoring (mean age 7.9 years).

Int J Clin Pharmacol TherOct 16, 2026Read summary
Clinical ResearchPathology (Anatomic & Clinical)Open access

SOX10 Expression in Primary Salivary Gland Tumors: A Meta-Analysis.

This PRISMA-guided systematic review and meta-analysis assessed SOX10 immunohistochemical expression across primary salivary gland tumors. It included 35 studies comprising 1146 histological and 35 cytological samples.

Head Neck PatholOct 16, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

Adenotonsillectomy for children with mild sleep-disordered breathing: who benefits?

This secondary analysis of a 12-month, multicentre randomised trial examined children aged 3.0–12.9 years with mild sleep-disordered breathing, comparing early adenotonsillectomy (eAT) with watchful waiting and…

SleepOct 13, 2026Read summary
Clinical ResearchPlastic SurgeryOpen access

Anatomical variation in the cervical branch of the facial nerve: a systematic review.

There is a paucity of literature on the anatomical variations of the cervical branch of the facial nerve (CBFN). Poor awareness of its anatomy and variations risks intraoperative damage, misdiagnosis of facial nerve…

Surg Radiol AnatOct 12, 2026Read summary
Clinical ResearchPulmonology

Effectiveness of a fully digital mandibular advancement appliance compared with CPAP in the treatment of obstructive sleep apnea.

This crossover clinical study compared a fully digital mandibular advancement appliance (MAA) with CPAP in 20 adults with obstructive sleep apnea (OSA), confirmed by polysomnography and non-adherent to CPAP.

Dental Press J OrthodOct 12, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

Comparison of the Efficacy of Appiani and Zuma Maneuvers in Patients with Apogeotropic Horizontal Canal Benign Paroxysmal Positional Vertigo.

This prospective randomized comparative study evaluated the Appiani and Zuma repositioning maneuvers in patients with unilateral apogeotropic horizontal canal benign paroxysmal positional vertigo.

J Int Adv OtolOct 9, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Boesenbergia rotunda extract-based mucoadhesive mouth gargle for chemoradiation-induced oral mucositis: A prospective randomized controlled study.

This randomized controlled trial evaluated the efficacy of a Boesenbergia rotunda extract-based mouth gargle in managing chemoradiation-induced oral mucositis in head and neck cancer patients.

Support Care CancerOct 3, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Intraoperative Dexmedetomidine and Postoperative Delirium After Head and Neck Cancer Surgery with Free-Flap Reconstruction: A Secondary Analysis of a Randomized Placebo-Controlled Trial.

This delirium-focused secondary analysis of a single-centre, randomized, double-blind, placebo-controlled trial examined adults undergoing elective head and neck cancer surgery with free-flap reconstruction.

Drug Des Devel TherOct 2, 2026Read summary

September 202611

Clinical ResearchOncology (Medical)

Coffee consumption and head and neck cancer risk: a dose-response and site-specific meta-analysis.

This meta-analysis examined the relationship between coffee consumption and head and neck cancer (HNC) risk across 30 studies.

Eur J Cancer PrevSep 30, 2026Read summary
Clinical ResearchAllergy & Immunology

Short-term nasal decongestant as bridge therapy with intranasal corticosteroids in children with persistent allergic rhinitis: A randomized controlled trial.

This prospective, open-label, single-centre randomised trial compared intranasal corticosteroid (INS) alone with INS plus five days of oxymetazoline in children aged 4–17 years with moderate-to-severe persistent…

Int J Pediatr OtorhinolaryngolSep 29, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

Non-usage rates after paediatric cochlear implantation: A systematic review and meta-analysis.

This systematic review and meta-analysis examined long-term cochlear implant use among paediatric recipients, synthesising 29 studies involving 2,595 children.

Int J Pediatr OtorhinolaryngolSep 28, 2026Read summary
Clinical ResearchOtolaryngology (ENT)Open access

Utilization of human amniotic membrane (HAM) in tympanoplasty: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the use of human amniotic membrane (HAM) as a graft material in tympanoplasty, analyzing data from eight studies involving 265 tympanoplasties.

Cell Tissue BankSep 24, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

Acoustic rhinometry for the assessment of adenoid hypertrophy: A systematic review.

This systematic review assessed acoustic rhinometry (AR) for diagnosing and evaluating adenoid hypertrophy in children. Thirteen studies included 650 participants (563 patients and 87 controls).

Int J Pediatr OtorhinolaryngolSep 21, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

Automated pure tone audiometry (PTA) in the assessment of hearing loss in pediatric populations: A systematic review and meta-analysis of diagnostic test accuracy studies.

This systematic review and meta-analysis assessed the diagnostic accuracy of automated pure-tone audiometry (PTA) for hearing loss in children. Twelve studies were included.

Int J Pediatr OtorhinolaryngolSep 18, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

Safety and Analgesic Outcomes of Nonsteroidal Anti-Inflammatory Drug-Containing Regimens After Transoral Robotic Surgery: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed postoperative hemorrhage and analgesic outcomes with NSAID-containing regimens after transoral robotic surgery (TORS).

Head NeckSep 11, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

Comparison of therapeutic results with/without additional electroacupuncture therapy in sudden sensorineural hearing loss with anxiety or depression: A randomized controlled trial.

This randomized controlled trial evaluated the effects of adding electroacupuncture (EA) to standard pharmacotherapy in 78 patients with sudden sensorineural hearing loss (SSNHL) and comorbid anxiety or depression.

Pak J Pharm SciSep 6, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Neoadjuvant combined immunotherapy with intratumoral TransCon TLR7/8 Agonist and systemic TransCon IL-2 β/y or pembrolizumab in patients with locally advanced oral cancer-a monocentric experience.

Combination immunotherapy has shown encouraging activity across multiple solid tumors. We report the complete and consecutive cohort of patients with locally advanced oral squamous cell carcinoma (OSCC) treated at a…

Cancer Immunol ImmunotherSep 4, 2026Read summary
Clinical ResearchOtolaryngology (ENT)Open access

Anatomical determinants of sphenoid sinus volume: insights from a meta-analysis of observational studies.

This meta-analysis examined the anatomical determinants of sphenoid sinus volume across 27 studies with 1263 observations. The pooled mean total sphenoid sinus volume was 9.30 cm³, with significant increases observed…

Surg Radiol AnatSep 2, 2026Read summary
Clinical ResearchPlastic SurgeryOpen access

The Effects of Remote Ischemic Preconditioning on the Inflammatory Cytokine Response to Free Flap Head and Neck Reconstruction: A Randomized Controlled Trial.

This randomized controlled trial investigated the impact of remote ischemic preconditioning (RIPC) on inflammatory cytokine levels in 60 head and neck cancer patients undergoing free flap reconstruction.

MicrosurgerySep 1, 2026Read summary

August 20263

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