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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

FeaturedClinical ResearchOncology (Medical)

High-dose radiotherapy in patients with high-risk prostate cancers treated with long-term androgen deprivation therapy (GETUG AFU 18): a randomised, phase 3 trial.

Lancet OncolSep 1, 2026

This multicenter, open-label, randomized phase 3 trial evaluated the impact of dose-escalated radiotherapy (80 Gy) versus standard radiotherapy (70 Gy) on progression-free survival in 505 men with high-risk prostate…

Why it matters

The findings suggest that higher doses of radiotherapy may enhance progression-free survival in high-risk prostate cancer patients, which could influence treatment strategies and patient outcomes in this population.

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Also worth knowing

Clinical ResearchOncology (Medical)

The role of particle therapy in the treatment of locally recurrent rectal cancer: a systematic review.

This systematic review evaluated the role of particle therapy in treating locally recurrent rectal cancer, particularly in patients with unresectable or inoperable cases.

Radiol OncolSep 7, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Single-fraction stereotactic radiosurgery vs. hypofractionated stereotactic radiotherapy for resected brain metastases: a systematic review and meta-analysis of comparative studies.

This systematic review and meta-analysis evaluated the effectiveness of single-fraction stereotactic radiosurgery (SF-SRS) versus hypofractionated stereotactic radiotherapy (HF-SRT) in adults with resected brain…

Neurosurg RevSep 5, 2026Open accessRead summary
Clinical ResearchNeurology

Imaging‑based models for predicting cerebrovascular complications of carotid stenosis.

This systematic review protocol aims to evaluate multivariable prognostic models using imaging biomarkers to predict cerebrovascular complications in adults with carotid stenosis.

Cochrane Database Syst RevSep 9, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Robotic Needle Insertion for CT-guided Percutaneous Biopsy of Thoracoabdominal Lesions: A Prospective Multicenter Randomized Trial.

This prospective multicenter randomized trial evaluated the safety and feasibility of a robotic system versus conventional freehand technique for CT-guided percutaneous biopsy of thoracoabdominal lesions in 165…

Radiol Imaging CancerSep 1, 2026Read summary
Clinical ResearchRheumatology

The utility of 18F-fluorodeoxyglucose PET/computed tomography in relapsing polychondritis: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the utility of 18F-fluorodeoxyglucose PET/CT in relapsing polychondritis, analyzing data from three studies involving 97 patients.

Nucl Med CommunSep 8, 2026Read summary
Clinical ResearchCardiology

Effect of low-dose rivaroxaban plus aspirin on 18F-FDG PET/CT-detectable carotid plaque inflammation: a randomized trial.

This randomized controlled trial evaluated the effect of low-dose rivaroxaban combined with aspirin on carotid plaque inflammation in 92 adults with asymptomatic carotid stenosis.

Eur Heart J Cardiovasc ImagingSep 1, 2026Read summary
Clinical ResearchOncology (Medical)

Value of shear wave elastography in evaluating response to neoadjuvant chemotherapy in breast cancer: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness of shear wave elastography in assessing the pathological response to neoadjuvant chemotherapy in breast cancer patients.

J Int Med ResSep 3, 2026Read summary
Clinical ResearchNeurology

Synaptic vesicle glycoprotein 2A PET imaging in parkinsonian α-synucleinopathies: a systematic review.

This systematic review evaluated the use of synaptic vesicle glycoprotein 2A (SV2A) PET imaging in assessing presynaptic integrity in parkinsonian α-synucleinopathies, including Parkinson's disease (PD), Parkinson's…

J NeurolSep 7, 2026Open accessRead summary
Clinical ResearchRadiology (Diagnostic)

Diagnostic accuracy of artificial intelligence tools in evaluating the inferior alveolar nerve-third molar relationship: a systematic review.

This systematic review evaluated the diagnostic accuracy of artificial intelligence (AI) tools in assessing the relationship between the inferior alveolar nerve (IAN) and third molars.

Dentomaxillofac RadiolSep 1, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Failure modes and effects analysis for clinical implementation of online adaptive radiotherapy: A systematic review.

This systematic review examined the application of Failure Modes and Effects Analysis (FMEA) in Online Adaptive Radiotherapy (OART) across various systems.

J Appl Clin Med PhysSep 1, 2026Open accessRead summary
Clinical ResearchOncology (Medical)

The role of stereotactic radiosurgery for prostate cancer spine metastasis - impact on hormone sensitivity and treatment outcomes: a systematic review of literature.

This systematic review evaluated the outcomes of stereotactic body radiotherapy (SBRT) for spinal metastases in prostate cancer, focusing on hormone-sensitive (HSPC) versus castration-resistant (CRPC) disease.

Neurosurg RevSep 1, 2026Open accessRead summary

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