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63 articles
October 202611
Systemic Spiroplasma turonicum Infection Manifested as Knee Arthritis, France, 2025.
An immunocompromised patient in southeast France presented with fever, knee arthritis, and skin erythema. Blood and joint samples tested positive for Spiroplasma turonicum, an intracellular gram-negative bacterium…
Unexpected finding of AA amyloidosis with novel genetic variants in the MEFV gene in patients undergoing kidney biopsy for proteinuria. A case series.
The report describes patients undergoing kidney biopsy for proteinuria in whom AA amyloidosis was identified, alongside MEFV gene variants.
Effectiveness of tocilizumab monotherapy for IgG4-related disease-like features caused by idiopathic multicentric Castleman's disease: a case-based review.
A 68-year-old woman presented with dyspnea associated with a recurrent laryngeal tumor, pulmonary consolidation, mediastinal and axillary lymphadenopathy, sclerosing mesenteritis, and retroperitoneal fibrosis.
SARS-CoV2-induced Schnitzler syndrome, inflammatory flare and successful treatment by anakinra during pregnancy: a case report.
A pregnant woman in her early 40s with established Schnitzler syndrome developed urticaria, musculoskeletal symptoms and elevated inflammatory markers during SARS-CoV-2 infection, consistent with an inflammatory flare.
Oral mucous membrane pemphigoid as a window to systemic autoimmunity: two cases associated with rheumatoid arthritis and Sjögren's disease.
Two women presented with oral mucous membrane pemphigoid (MMP) in the setting of systemic autoimmunity. A 68-year-old woman with longstanding rheumatoid arthritis had recurrent oral ulcerations confirmed as MMP on…
Tocilizumab for active rheumatoid arthritis in a patient with concomitant primary biliary cholangitis: a case based review.
A 59-year-old woman presented with highly active, seropositive rheumatoid arthritis and marked cholestatic biochemical activity. Evaluation identified active primary biliary cholangitis without advanced liver fibrosis.
Exploring the landscape of flagellate erythema as a rare cutaneous symptom of idiopathic inflammatory myopathy: a case series-based review.
Two patients with idiopathic inflammatory myopathy developed zebra-like flagellate erythema: one had immune-mediated necrotising myopathy and the other anti-Mi-2-positive cancer-associated myositis.
Haemophagocytic lymphohistiocytosis triggered by Kikuchi-Fujimoto disease: a diagnostic challenge.
A man in his 40s presented with fever, confusion, a widespread erythematous rash, weight loss, and generalized lymphadenopathy over three weeks.
Gastrointestinal manifestations of IgA vasculitis guiding treatment in an adult patient.
A man in his 20s presented with abdominal pain, post-prandial vomiting, a purpuric rash, arthralgia, and hypertension. Urine studies indicated subnephrotic range proteinuria, and colonoscopy revealed ileal ulceration.
Uveitis despite adalimumab therapy in Blau syndrome.
A middle childhood boy initially diagnosed with oligoarticular juvenile idiopathic arthritis presented with persistent arthritis, recurrent fever, and skin lesions.
Adult-Onset Henoch-Schönlein Purpura Triggered by Isotretinoin with Persistent Polyarthritis and Isolated Cutaneous-Gastrointestinal Involvement: A Case Report.
A 30-year-old woman developed palpable purpura, abdominal pain, and symmetric polyarthritis three weeks after starting isotretinoin.
September 202613
Metastatic melanoma presenting with paraneoplastic dermatomyositis mimicking polymyalgia rheumatica.
A man in his late 70s presented with bilateral shoulder and hip girdle pain, morning stiffness, and significant weight loss over six weeks.
Takayasu arteritis manifesting as pyrexia of unknown origin and massive splenomegaly.
A male patient in his early 20s presented with a three-month history of pyrexia of unknown origin, significant weight loss, a left carotid bruit, and massive splenomegaly.
Drug-Induced Liver Injury During Treatment With Tocilizumab: A Case Report of an Atypical Pattern Lesion.
A 75-year-old patient with giant cell arteritis developed jaundice and abdominal pain after the third infusion of tocilizumab.
Male Systemic Lupus Erythematosus: A Rare Case of Multisystem Involvement.
A 31-year-old man with systemic lupus erythematosus presented with fatigue, joint pain, fever, and a photosensitive rash. Laboratory tests revealed positive antinuclear antibodies and elevated anti-double-stranded DNA…
Scalp necrosis and visual loss in giant cell arteritis: the importance of recognising atypical cutaneous clues.
A 70-year-old woman presented with left hemifacial pain and bilateral forehead skin plaques, initially diagnosed as shingles.
Non-Radiographic Axial Spondyloarthritis Presenting with Anterior Chest Wall Pain without Inflammatory Back Pain in an HLA-B27-Negative Young Man: A Case Report Highlighting Diagnostic Challenges.
A 22-year-old HLA-B27-negative male presented with mild anterior chest wall pain, initially deemed mechanical and treated with NSAIDs.
Septic arthritis mimic unmasked: inflammatory bowel disease-associated arthritis in a patient with a learning disability.
A man in his early 30s with a mild learning disability presented with acute left-knee pain, swelling, erythema, and fevers, alongside low-back and hip pain.
Takayasu Arteritis in a 15-Year-Old Male Presenting with Constitutional Symptoms and Upper Limb Pulse Deficit: A Case Report a Resource-Limited Settings.
A 15-year-old male presented with several months of low-grade fever, fatigue, and joint pain, culminating in chest pain, vomiting, and significant weight loss.
Kikuchi-Fujimoto Disease Associated with Hashimoto's Thyroiditis: A Case Report.
A 37-year-old woman with a history of Hashimoto's thyroiditis presented with rapidly enlarging cervical lymphadenopathy. Laboratory tests indicated mild anemia and elevated ESR, while ultrasound revealed multiple…
Unraveling the Clinical Spectrum of DNASE1L3 Deficiency: Insights from Case Series and Systematic Literature Review.
This case series examined four children with genetically confirmed biallelic DNASE1L3 variants, revealing a diverse clinical spectrum of immune-mediated diseases.
Multidisciplinary management of an older adult with vascular Ehlers-Danlos syndrome and multiple autoimmune comorbidities.
An early 60s female with vascular Ehlers-Danlos syndrome (vEDS) presented with extensive comorbidities, including systemic lupus erythematosus and rheumatoid arthritis.
Allogeneic CD19 CAR-NK cell therapy for a patient with relapsed and refractory lupus nephritis.
A patient with severe relapsed and refractory lupus nephritis, unresponsive to standard treatments, received allogeneic CD19 CAR-NK cell therapy following lymphodepleting chemotherapy.
Clinical and immunological characterization of a child with a homozygous TBK1 kinase-domain truncation.
TBK1 is a serine-tyrosine kinase protein that transmits signals from pattern recognition receptors to the NF-κB pathway leading to production of Type 1 Interferons.
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