Candidemia in a Preterm Neonate at Ladoke Akintola University of Technology Teaching Hospital, Ogbomoso, South West, Nigeria.
Olusola Adetunji Oyedeji, Muideen Abiodun Ogunyode, Bukola Adetutu Sayomi et al.
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Case in brief
A 36-week preterm, low-birth-weight male infant developed signs of neonatal sepsis shortly after vaginal delivery. His mother had untreated vaginal candidiasis around the time of delivery. The infant did not improve with the conventional antibiotics used locally for neonatal sepsis; blood culture subsequently grew Candida albicans. He improved after oral fluconazole therapy.
What made this case unusual
The report links neonatal candidemia with maternal untreated vaginal candidiasis and describes improvement with oral fluconazole after conventional antibiotics failed.
Diagnostic / clinical pearl
In a neonate with sepsis unresponsive to conventional antibiotics, blood culture can identify candidemia and guide recognition of Candida albicans infection.