The efficacy and mechanism of an integrated mindfulness-based programme on posttraumatic stress disorder among people with HIV: a randomized controlled trial with 3-month follow up.
Chulei Tang, Ting Zhao, Simin Yu et al.
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In 30 seconds
This randomized controlled trial evaluated an Integrated Mindfulness-Based Programme (IMBP), combining the Community Resiliency Model and mindfulness-based stress reduction, in 82 people with HIV and PTSD. Compared with a control group, participants assigned to IMBP had significantly greater reductions in PTSD symptoms and improvements in antiretroviral therapy adherence immediately after the intervention and at 3-month follow-up (all p < .01). Mediation analyses indicated that increased mindfulness and resilience, and reduced rumination, partially mediated the intervention’s effect on PTSD symptoms.
Key findings
- IMBP produced greater reductions in PTSD symptoms than control immediately after treatment and at 3-month follow-up (all p < .01).
- Antiretroviral therapy adherence improved more with IMBP than control at both assessment points (all p < .01).
- Increased mindfulness and resilience, and decreased rumination, partially mediated the effect on PTSD symptoms.
Why it matters
PTSD symptoms and treatment adherence are both relevant to the care of people with HIV. This trial suggests that an integrated programme may address these outcomes together, while its mediation findings point to mindfulness, resilience, and rumination as possible pathways. The results add evidence for a psychosocial intervention tailored to people with HIV who have PTSD.
What to keep in mind
The abstract does not report effect sizes or details of the intervention and control conditions, limiting assessment of the magnitude and practical interpretation of the reported differences.