A global overview of microsporidia infection in HIV/AIDS patients: an updated systematic review and meta-analysis.

Int HealthSep 1, 2026
Clinical ResearchInfectious DiseasesInternal Medicine (General)Open access

Ali Asghari, Mohammad Reza Mohammadi, Roumina Norouzi et al.

✦ AI-curated · Sources linked

In 30 seconds

This systematic review and meta-analysis evaluated the prevalence and species distribution of microsporidia in HIV/AIDS patients, analyzing 39 studies from 18 countries. The pooled prevalence was found to be 12% (95% CI 8.9 to 16), significantly higher than the 1.9% in controls, with notable increases in specific populations and regions.

Key findings

  • Pooled prevalence of microsporidia in HIV/AIDS patients was 12% (95% CI 8.9 to 16).
  • The odds ratio for microsporidia infection in HIV/AIDS patients compared to controls was 5.7 (95% CI 3.33 to 9.74).
  • Prevalence was higher in patients with CD4 counts ≤200 cells/μl at 58.4%.
  • The predominant species identified was Enterocytozoon bieneusi, with 24 genotypes.

Why it matters

Understanding the prevalence and distribution of microsporidia in HIV/AIDS patients is crucial for improving diagnostic and treatment strategies. This knowledge can help clinicians better manage opportunistic infections and enhance patient outcomes.

Source

PubMed · PMID 41601338Free full text on PubMed Central

Published in Int Health. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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