Fatal Fungal Peritonitis Caused by Aspergillus udagawae: An Autopsy Case Report.
Kengo Nishino, Takumi Kiwamoto, Chio Sakai et al.
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Case in brief
A 56-year-old man with chronic progressive pulmonary aspergillosis caused by multidrug-resistant Aspergillus udagawae developed acute abdominal pain. Computed tomography showed a ruptured intra-abdominal abscess and ascites. He underwent emergency surgery for peritonitis but died on day 5. Autopsy revealed multiple fungal abscesses and showed direct invasion and hematogenous spread from the lungs to the peritoneum. Genetic analysis confirmed A. udagawae as the causative organism.
What made this case unusual
Autopsy established fatal fungal peritonitis from pulmonary A. udagawae infection, with both direct invasion and hematogenous spread to the peritoneum.
Diagnostic / clinical pearl
In treatment-refractory Aspergillus infection, molecular identification can clarify the causative species; in this case, genetic analysis confirmed A. udagawae.