COMBINATION OF METHOTREXATE AND MYCOPHENOLATE MOFETIL FOR REFRACTORY UVEITIS AND SCLERITIS: A Case SERIES.
Parthopratim Dutta Majumder, Ahana Sen, Rakshita Deepak Kene et al.
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Case in brief
This case series involved six patients, five with uveitis and one with scleritis, all of whom had treatment-resistant conditions. The patients, with a median age of 19.5 years, received a combination of methotrexate and mycophenolate mofetil after failing prior therapies. All patients achieved remission, with follow-up showing successful tapering of corticosteroids in most cases, indicating the efficacy of this combined treatment approach.
Diagnostic / clinical pearl
Clinicians should consider the combination of methotrexate and mycophenolate mofetil for patients with refractory uveitis and scleritis who do not respond to conventional immunosuppressive therapies.