Important medical research and remarkable case reports worth knowing.
Selected from high-relevance medical literature published in the last 14 days.
Two 52-week, double-blind, randomized, placebo-controlled phase III trials evaluated monthly or less frequent ianalumab in patients with active Sjögren's disease.
Why it matters
These trials provide randomized evidence that monthly ianalumab can modestly reduce measured disease activity in active Sjögren's disease over 48 weeks.
This systematic review and meta-analysis assessed autoimmune susceptibility in people with Klinefelter syndrome (47,XXY), using studies of autoimmune disease and serological markers.
This analysis of data from the ADHERE randomized controlled trial estimated the minimal important difference (MID) in EQ-5D-5 L utility values for patients with chronic inflammatory demyelinating polyradiculoneuropathy…
This systematic review and meta-analysis assessed imaging-based structural outcomes after platelet-rich plasma (PRP) treatment in people with knee osteoarthritis.
This 12-week, open-label, active-comparator randomized trial compared calorie-restricted carbohydrate-restricted, DASH, and low-purine balanced diets in 102 men with overweight or obesity and hyperuricemia.
This systematic review and meta-analysis examined glaucoma occurrence and risk among people with rheumatic diseases (RD), drawing on 18 studies with 5,766,143 participants.
This systematic review and meta-analysis compared anterior, posterior, and combined surgical approaches for cervical fractures in patients with ankylosing spondylitis.
This pilot prospective randomized controlled trial assessed whether active vitamin D3 or vitamin E added benefit to home exercise in postmenopausal women with symptomatic knee osteoarthritis.
This mixed methods, cluster-randomized controlled trial evaluated CrossCover, a web-based clinical decision support system for adult musculoskeletal consultations in UK general practice.
An immunocompromised patient in southeast France presented with fever, knee arthritis, and skin erythema. Blood and joint samples tested positive for Spiroplasma turonicum, an intracellular gram-negative bacterium…
A pregnant woman in her early 40s with established Schnitzler syndrome developed urticaria, musculoskeletal symptoms and elevated inflammatory markers during SARS-CoV-2 infection, consistent with an inflammatory flare.
The report describes patients undergoing kidney biopsy for proteinuria in whom AA amyloidosis was identified, alongside MEFV gene variants.
Showing 12 of 16 publications that cleared our clinical screen in the last 14 days.
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