Cervico-vaginal Amoebiasis Masquerading as Malignancy-A Case Series Highlighting Rare Clinical Presentation of a Common Parasitic Infection.
Neha Bakshi, Rahul D Modi, Mala Srivastava et al.
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Case in brief
Three women presented with lower genital tract lesions that appeared clinically and radiologically suspicious for malignancy. Cervical tissue examination established amoebiasis by identifying Entamoeba histolytica trophozoites, which may be recognized by ingested erythrocytes. Treatment with metronidazole was followed by complete clinical resolution in all three patients.
What made this case unusual
A rare extraintestinal infection produced ulcerated, necrotic, mass-like cervical or vulvovaginal lesions that mimicked malignancy on clinical and radiological assessment.
Diagnostic / clinical pearl
In women with atypical cervical or vulvovaginal lesions, especially those from endemic regions, tissue examination can distinguish amoebiasis from malignancy; trophozoites containing ingested erythrocytes support the diagnosis.