Seroprevalence of hepatitis C virus among refugees, asylum seekers, and internally displaced populations within Africa: A systematic review and meta-analysis.
Eleanor K Beddard, Getahun Molla Kassa, Josephine G Walker et al.
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In 30 seconds
This systematic review and random-effects meta-analysis assessed hepatitis C virus (HCV) seroprevalence among refugees, asylum seekers, and internally displaced people in Africa. Across 9 studies, pooled seroprevalence was 3.63% (95% CI: 0.54, 9.16). Estimates were higher among people from Northern Africa, at 10.03% (95% CI:9.03, 11.13), and among those aged >40 years, at 5.70% (95% CI: 0.81, 14.21). The authors report variation by region and age and suggest targeted screening approaches.
Key findings
- Across 9 studies, pooled HCV seroprevalence among African RASIDP was 3.63% (95% CI: 0.54, 9.16).
- Seroprevalence among participants from Northern Africa was 10.03% (95% CI:9.03, 11.13).
- Among participants aged >40 years, seroprevalence was 5.70% (95% CI: 0.81, 14.21).
Why it matters
The pooled estimate indicates that HCV is present in a population described as underserved and facing barriers to healthcare, while subgroup estimates suggest prevalence is not uniform. These findings can inform awareness of potential screening needs in displaced communities, although the estimates vary and do not establish the effectiveness of any screening strategy.
What to keep in mind
The meta-analysis included only 9 studies, and the pooled estimate had a wide confidence interval, indicating uncertainty in the overall prevalence estimate.