First Report on Remdesivir Use for the Treatment of Respiratory Syncytial Virus in Five Allogeneic Hematopoietic Cell Transplant Recipients.
Denise J McCulloch, Fareed Khawaja, Frank P Tverdek et al.
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Case in brief
Five allogeneic hematopoietic cell transplant recipients presented with lower respiratory tract infections caused by respiratory syncytial virus (RSV). They were treated with remdesivir, which had shown antiviral activity in vitro. All patients exhibited clinical improvement following treatment, suggesting potential efficacy of remdesivir in this patient population.
Diagnostic / clinical pearl
Remdesivir may be a promising treatment option for RSV infections in hematopoietic cell transplant recipients, where approved therapies are lacking.