Surgical versus percutaneous revascularization in multivessel non-ST-elevation acute coronary syndrome: a meta-analysis of 77 989 patients.
Coron Artery DisApr 27, 2026 (epub)
Mohammed A Elbahloul, Ahmed Elbataa, Momen Hajali et al.
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In 30 seconds
This meta-analysis compared coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) in 77,989 patients with multivessel non-ST-elevation acute coronary syndrome. CABG was associated with lower all-cause mortality (RR: 0.80, 95% CI: 0.68-0.93) and other major adverse cardiovascular events in long-term follow-up, while stroke incidence was higher with CABG.
Key findings
- CABG reduced all-cause mortality compared to PCI (RR: 0.80, 95% CI: 0.68-0.93).
- CABG was linked to lower rates of major adverse cardiovascular events (RR: 0.70, 95% CI: 0.59-0.83).
- Myocardial infarction rates were significantly lower with CABG (RR: 0.53, 95% CI: 0.42-0.67).
- Stroke incidence was higher with CABG (RR: 1.36, 95% CI: 1.07-1.73).
Why it matters
Understanding the comparative effectiveness of CABG versus PCI in this patient population is crucial for optimizing treatment strategies and improving long-term outcomes in patients with multivessel coronary artery disease.