Effects of Aerobic Exercise on Heart Rate Variability and C-Reactive Protein in Middle-Aged Adults With Normal Weight and Overweight/Obesity: A Pilot Study.

Res Nurs HealthMay 20, 2026 (epub)

Yu-Hsuan Chang, Shiow-Ching Shun, Wei-Li Hsu et al.

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In 30 seconds

This controlled clinical trial investigated the effects of a 16-week aerobic exercise program on heart rate variability (HRV) and C-reactive protein (CRP) in middle-aged adults with normal weight and overweight/obesity. The study found that the overweight/obesity group had a significant decrease in resting heart rate (Β = -4.35, p = 0.049) but an increase in CRP (Β = 1.22, p = 0.045) compared to the normal weight group.

Key findings

  • Overweight/obesity participants showed a significant decrease in resting heart rate (Β = -4.35, p = 0.049).
  • The same group experienced a significant increase in C-reactive protein (Β = 1.22, p = 0.045).
  • HRV parameters associated with parasympathetic activity fluctuated more in the normal weight group during exercise.

Why it matters

Understanding the differential responses to aerobic exercise based on body weight can help clinicians tailor exercise recommendations. Monitoring HRV and inflammation may enhance safety and effectiveness in exercise regimens for middle-aged adults.

Source

Published in Res Nurs Health. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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