Efficacy of BiPAP/CPAP versus COT in patients with obstructive sleep apnea or obesity undergoing sedated gastroenteroscopy: a meta-analysis.
Weizhong Wang, Pan Zhang, Ting Xu et al.
✦ AI-curated · Sources linked
In 30 seconds
This meta-analysis evaluated the efficacy of bilevel or continuous positive airway pressure (BiPAP/CPAP) versus conventional oxygen therapy (COT) in preventing hypoxemia during sedated gastroenteroscopy in patients with obstructive sleep apnea or obesity. The analysis included eight randomized controlled trials with 1012 patients, revealing that BiPAP/CPAP significantly reduced hypoxemia (OR 0.26) and severe hypoxemia (OR 0.15) compared to COT.
Key findings
- BiPAP/CPAP reduced hypoxemia compared to COT (OR 0.26, 95% CI 0.16-0.42).
- Severe hypoxemia was significantly lower with BiPAP/CPAP (OR 0.15, 95% CI 0.05-0.39).
- The need for jaw lift was reduced with BiPAP/CPAP (OR 0.21, 95% CI 0.14-0.32).
- No significant difference in nausea/vomiting was observed between the two therapies.
Why it matters
The findings suggest that BiPAP/CPAP may be a more effective option than conventional oxygen therapy for preventing hypoxemia in high-risk patients undergoing sedated gastroenteroscopy, potentially improving patient safety during these procedures.
What to keep in mind
The study lacked a blinded design and did not compare BiPAP/CPAP with high-flow nasal cannula therapy.