Avatar-led digital health intervention for sexual and gender minority young adult smoking cessation: randomized controlled pilot trial.

Nicotine Tob ResOct 22, 2026

Jaimee L Heffner, Kelsey Baker, Xinyi Fan et al.

✦ AI-curated · Sources linked

In 30 seconds

This randomized controlled pilot trial compared EQQUAL, an Acceptance and Commitment Therapy-based digital smoking cessation program tailored for sexual and gender minority (SGM) young adults, with Smokefree.gov. The 124 participants were aged 18–30 and smoked at least weekly; outcomes were assessed 3 months after randomization. Biochemically verified 7-day abstinence was 11.1% with EQQUAL versus 4.9% with Smokefree.gov (OR = 1.89, 95% CI = 0.45 to 9.66). Satisfaction was descriptively higher with EQQUAL, but readiness to quit, cigarettes per day, and theory-based change processes were similar between groups.

Key findings

  • Biochemically verified 7-day point prevalence abstinence was 11.1% with EQQUAL versus 4.9% with Smokefree.gov (OR = 1.89, 95% CI = 0.45 to 9.66).
  • Overall satisfaction was 68.8% with EQQUAL versus 60.0% with Smokefree.gov (OR = 1.17, 95% CI = 0.50 to 2.78).
  • EQQUAL usability exceeded the acceptable benchmark score of 68, but participants completed an average of 1.4 of 6 digital sessions.
  • Readiness to quit, cigarettes per day, and theory-based change-process outcomes were similar between groups.

Why it matters

SGM young adults face smoking cessation challenges, and accessible, culturally tailored support may help address this need. The pilot suggests that a tailored digital program can be acceptable and may have promising cessation outcomes compared with a general online program. However, the wide confidence interval and limited engagement mean the observed abstinence difference is preliminary rather than conclusive.

What to keep in mind

This was a pilot trial with 124 participants and outcomes assessed at 3 months; the abstinence estimate was imprecise, and average completion of EQQUAL sessions was low.

Source

Published in Nicotine Tob Res. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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