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FeaturedCase ReportEndocrinology

Primary Care Recognition of Rabson-Mendenhall Syndrome Despite Absence of Classical Diabetic Symptoms.

Am J Case RepSep 5, 2026

A 10-year-old girl presented with intermittent bilateral leg pain and excessive hunger, lacking classical diabetic symptoms. Examination revealed extensive acanthosis nigricans, moderate hirsutism, and dental defects.

Clinical pearl

Clinicians should consider genetic insulin resistance syndromes like Rabson-Mendenhall syndrome in patients with severe hyperinsulinemia and atypical features, even in the absence of classical diabetic symptoms.

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Also worth knowing

Clinical ResearchInfectious Diseases

Implementation, adoption and impact of clinical decision support system for antibiotic prescribing in primary care: a systematic review.

This systematic review evaluated the implementation and impact of clinical decision support systems (CDSS) for antibiotic prescribing in primary care, analyzing 40 studies.

J Antimicrob ChemotherSep 1, 2026Open accessRead summary

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