Changes in nasal and oral microbiota composition during a 10-day decolonization course with mupirocin and povidone-iodine: A real-world case series.
Thomas C Scheier, Tomas Demeter, Jessica Franz et al.
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Case in brief
Three adults with oral MRSA colonization underwent a 10-day decolonization treatment involving mupirocin and povidone-iodine. Throughout the treatment, significant fluctuations in the relative abundances of oral microbiota were observed, suggesting varied ecological responses to the decolonization approach. The study emphasizes the dynamic nature of oral microbiota during treatment and its potential role in MRSA decolonization.
Diagnostic / clinical pearl
Clinicians should consider the dynamic shifts in oral microbiota when managing MRSA decolonization, as these changes may influence treatment outcomes.
Why it matters
Understanding the role of oral microbiota in MRSA colonization can lead to more personalized and effective decolonization strategies.