Prognostic factors in malaria patients with acute kidney injury: a systematic review and meta analysis.
Ren FailMay 25, 2026 (epub)
Alveron Andreas Tear, Nisa Fauziah, Silvita Fitri Riswari et al.
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In 30 seconds
This systematic review and meta-analysis evaluated mortality predictors in malaria patients with acute kidney injury (AKI), analyzing data from 16 studies involving 1,104 patients. Key findings indicated that respiratory distress syndrome (OR: 18.50), neurological involvement (OR: 12.83), and hypotension (OR: 18.23) were significantly associated with increased mortality risk.
Key findings
- Respiratory distress syndrome was associated with an odds ratio of 18.50 for mortality.
- Neurological involvement had an odds ratio of 12.83, indicating a strong mortality risk.
- Hypotension was linked to an odds ratio of 18.23 for increased mortality.
- Ventilator requirement showed the highest odds ratio of 30.35 for mortality risk.
Why it matters
Understanding the prognostic factors associated with mortality in malaria patients with AKI is crucial for clinicians. It aids in identifying high-risk patients and implementing timely interventions to improve outcomes.