Inflammatory Pseudotumor Due to Actinomycosis Simulating Post-Transplant Lymphoproliferative Disorder.
Grecia Lizzetti-Mendoza, Daniel Reis Waisberg, Gabriel Bayona-Alvarado et al.
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Case in brief
A female liver transplant recipient presented with a hepatic collection after experiencing biliary complications. Imaging suggested a possible abscess, but the clinical response to initial treatment was poor, raising concerns for post-transplant lymphoproliferative disorder. A liver biopsy revealed Actinomyces sp., confirming hepatic actinomycosis. Treatment with intravenous ampicillin resulted in significant improvement and near-complete resolution of the lesion.
Diagnostic / clinical pearl
Hepatic actinomycosis can mimic malignant tumors in immunosuppressed patients, making it crucial to consider this diagnosis when evaluating atypical hepatic masses.
Why it matters
Recognizing hepatic actinomycosis in liver transplant recipients can prevent misdiagnosis and ensure appropriate management, which typically involves prolonged antibiotic therapy.