Clinical efficacy of chronotherapy-based auricular acupoint therapy combined with CPAP in comorbid obstructive sleep apnea and insomnia.
Fei-Fei Lin, Yao-Qi Xu, Jie-Ru Wu et al.
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In 30 seconds
This randomized controlled trial evaluated the efficacy of chronotherapy-based auricular acupoint therapy combined with CPAP in 114 patients with comorbid obstructive sleep apnea and insomnia (COMISA). Results showed significant improvements in sleep quality and respiratory function, with the chronotherapy group demonstrating greater reductions in Pittsburgh Sleep Quality Index and Insomnia Severity Index scores compared to the control group.
Key findings
- Significant reductions in apnea-hypopnea index and Epworth Sleepiness Scale scores across all groups (p < 0.05).
- Both intervention groups showed significant decreases in Pittsburgh Sleep Quality Index and Insomnia Severity Index scores (p < 0.05).
- Chronotherapy-based therapy resulted in significantly lower PSQI, ESS, and ISI scores compared to conventional therapy (p < 0.05).
Why it matters
Improving sleep quality and reducing daytime sleepiness in patients with COMISA can enhance overall health outcomes. This study suggests that integrating chronotherapy with CPAP may provide additional benefits over standard treatments.