Successful eravacycline monotherapy for cefiderocol-resistant Acinetobacter baumannii bloodstream infection in a critically ill patient with concomitant Clostridioides difficile colitis.

Int J Infect DisJun 2, 2026 (epub)
Case ReportInfectious Diseases

Luca Pipitò, Antonio Anastasia, Giulio D'Agati et al.

✦ AI-curated · Sources linked

Case in brief

An 87-year-old critically ill woman with multiple comorbidities developed a bloodstream infection caused by cefiderocol-resistant Acinetobacter baumannii during hospitalization, alongside Clostridioides difficile colitis. After confirming resistance, her treatment was switched to eravacycline monotherapy. Following 14 days of treatment, she showed clinical improvement and achieved blood culture sterilization within 96 hours.

Diagnostic / clinical pearl

In cases of cefiderocol-resistant Acinetobacter baumannii, eravacycline may be an effective alternative, even in the context of concurrent Clostridioides difficile infection.

Source

PubMed · PMID 42235915

Published in Int J Infect Dis. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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