Case report:Maribavir for refractory CMV infection in 2 pediatric HSCT recipients.

Diagn Microbiol Infect DisMay 28, 2026 (epub)
Case ReportInfectious DiseasesPediatrics

ShuWen Huang, Heng OuYang, ZhiTing Zhang et al.

✦ AI-curated · Sources linked

Case in brief

Two pediatric patients with refractory cytomegalovirus (CMV) infection post-hematopoietic stem cell transplantation (HSCT) were treated with maribavir after conventional therapies failed. The first case involved concurrent CMV and Epstein-Barr virus activation with severe hepatic impairment, while the second progressed to CMV encephalitis. Both patients achieved favorable clinical outcomes with maribavir, demonstrating its potential efficacy and tolerability.

Diagnostic / clinical pearl

Maribavir may be a viable salvage therapy for pediatric patients with refractory CMV infections post-HSCT, especially when conventional antiviral treatments are ineffective.

Source

PubMed · PMID 42250353

Published in Diagn Microbiol Infect Dis. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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