Multisystem Detection and Molecular Evidence Linking Dog-Associated Ticks to Two Fatal Human SFTSV Infections in Thailand.
Sarawut Khongwichit, Sethapong Lertsakulbunlue, Nattapol Pruetpongpun et al.
✦ AI-curated · Sources linked
Case in brief
Two patients in Thailand presented with severe fever with thrombocytopenia syndrome (SFTS), confirmed by quantitative reverse transcription polymerase chain reaction. Viral RNA was found in various specimens, indicating systemic infection. Rhipicephalus sanguineus ticks from pet dogs and the patients' households also tested positive for SFTSV RNA, linking the ticks to the human cases. Both patients ultimately succumbed to the infection.
What made this case unusual
The detection of SFTSV RNA in dog-associated Rhipicephalus sanguineus ticks provides molecular evidence of a potential zoonotic transmission pathway, which is not commonly reported.
Diagnostic / clinical pearl
Clinicians should maintain a high index of suspicion for SFTS in dengue-endemic regions, especially when patients present with severe febrile illness and thrombocytopenia.
Why it matters
This case highlights the need for integrated surveillance of human, animal, and vector populations to better understand and manage emerging tick-borne diseases in Southeast Asia.