Integrated Telehealth Rehabilitation and Quality of Life in Mechanically Ventilated Adults: A Randomized Clinical Trial.
JAMASep 15, 2026
Clinical ResearchPulmonologyInternal Medicine (General)Physical Medicine & RehabilitationOpen access
Regis Goulart Rosa, Rafael Barberena Moraes, Geraldine Trott et al.
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In 30 seconds
This randomized clinical trial evaluated the impact of an integrated telehealth rehabilitation program on health-related quality of life in 1916 adults with acute hypoxemic respiratory failure requiring mechanical ventilation. At 90 days post-discharge, the intervention group had a higher mean EQ-5D-3L utility score of 0.16 compared to 0.12 in the usual care group (P = .04) and lower 90-day all-cause mortality (71.8% vs 78.3%, P = .03).
Key findings
- The intervention group had a higher mean EQ-5D-3L utility score of 0.16 compared to 0.12 in usual care (P = .04).
- 90-day all-cause mortality was lower in the intervention group at 71.8% compared to 78.3% in usual care (P = .03).
- Mean duration of mechanical ventilation was shorter in the intervention group, 9.9 days versus 15.5 days (P < .001).
Why it matters
Improving health-related quality of life and reducing mortality in patients recovering from acute respiratory failure is crucial for enhancing patient outcomes and resource utilization in healthcare settings.