Bundle implementation for reduction of central venous catheter associated bloodstream infections in pediatric intensive care unit - A systematic review.
Hanna Clemente Rosenvald, Luiza Duarte de Barros, Hyan Bacelete et al.
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In 30 seconds
This systematic review evaluated the effectiveness of care bundles in reducing central line-associated bloodstream infections (CLABSI) in pediatric intensive care units (PICUs). Analyzing 23 studies, it found that post-intervention CLABSI rates ranged from 0.7 to 14.3 per 1000 catheter-days, with over half of the studies reporting reductions greater than 50%.
Key findings
- Baseline CLABSI rates ranged from 2.0 to 25.2 per 1000 catheter-days.
- Post-intervention rates ranged from 0.7 to 14.3 per 1000 catheter-days.
- Over half of the studies reported a reduction in CLABSI rates superior to 50%.
Why it matters
Understanding the effectiveness of care bundles in reducing CLABSI rates is crucial for improving patient safety and outcomes in pediatric intensive care settings. Implementing these bundles can lead to significant reductions in infection rates.
What to keep in mind
Methodological weaknesses in the included studies limited the reliability of effect estimates.